1
40
4
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1006/cbir.1993.1042" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/cbir.1993.1042</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1091-1105
Issue
12
Volume
17
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effect Of Ethidium On The Morphology, Antiviral Activity And Subcellular-distribution Of Poly R(a-u)
Publisher
An entity responsible for making the resource available
Cell Biology International
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-12
Subject
The topic of the resource
agents; binding; Cell Biology; complex; delivery; dna; double-stranded-rna; human interferon; induction; inhibition; microscopy
Creator
An entity primarily responsible for making the resource
Jamison J M; Gilloteaux J J; Adrian M; Summers J L
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1006/cbir.1993.1042" target="_blank" rel="noreferrer noopener">10.1006/cbir.1993.1042</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1993
Adrian M
agents
Binding
Cell Biology
Cell biology international
complex
Delivery
DNA
double-stranded-rna
Gilloteaux J J
human interferon
induction
inhibition
Jamison J M
Journal Article or Conference Abstract Publication
Microscopy
Summers J L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1006/cbir.2001.0818" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/cbir.2001.0818</a>
Pages
131–144
Issue
2
Volume
26
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pertubation of beta1 integrin function using anti-sense or function-blocking antibodies on corneal cells grown on fibronectin and tenascin.
Publisher
An entity responsible for making the resource available
Cell biology international
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
1905-6
Subject
The topic of the resource
Animals; Antisense/*pharmacology; Cattle; Cell Adhesion; Cell Culture Techniques/*methods; Cells; Chick Embryo; Chickens; Complementary/metabolism; Cornea/*cytology; Cultured; DNA; Dose-Response Relationship; Drug; Fibronectins/*metabolism; Fluorescence; Immunohistochemistry; Integrin beta1/*metabolism/*physiology; Integrins/metabolism; Microscopy; Oligonucleotides; Protein Binding; Retroviridae/genetics; Tenascin/*metabolism
Creator
An entity primarily responsible for making the resource
Doane Kathleen J; Bhattacharya Raka; Marchant Jeff
Description
An account of the resource
During corneal development, neural crest derivatives from the periocular mesenchyme migrate into the cornea and differentiate into corneal fibroblasts. During this time, these cells interact with a variety of extracellular matrices for proper orientation and development. In the present studies, we have examined the interaction of beta(1) integrins on periocular mesenchyme cells (POM) and corneal fibroblasts (CF) with fibronectin and tenascin by perturbing the function of this integrin. POM and CF attached and spread to a much greater extent on fibronectin than on tenascin. An antibody against beta(1) integrin, CSAT, decreased spreading and attachment, and resulted in a lack of immuno-detectable beta(1) integrin in focal adhesions on fibronectin; few beta(1) positive focal adhesions were observed in cells grown on tenascin. An anti-sense retroviral construct decreased endogenous levels of beta(1) integrin protein, and caused decreased attachment and spreading as well as sparse, disorganized focal adhesions. These data indicate that in vitro, both POM and CF have beta(1) integrins that interact with fibronectin and allow them to attach and spread, while tenascin is anti-adhesive. Further studies using both of these experimental paradigms will clarify whether these interactions also occur in vivo.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1006/cbir.2001.0818" target="_blank" rel="noreferrer noopener">10.1006/cbir.2001.0818</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2002
Animals
Antisense/*pharmacology
Bhattacharya Raka
Cattle
Cell Adhesion
Cell biology international
Cell Culture Techniques/*methods
Cells
Chick Embryo
Chickens
Complementary/metabolism
Cornea/*cytology
Cultured
DNA
Doane Kathleen J
Dose-Response Relationship
Drug
Fibronectins/*metabolism
Fluorescence
Immunohistochemistry
Integrin beta1/*metabolism/*physiology
Integrins/metabolism
Marchant Jeff
Microscopy
Oligonucleotides
Protein Binding
Retroviridae/genetics
Tenascin/*metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1006/cbir.1993.1014" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/cbir.1993.1014</a>
Pages
919–934
Issue
10
Volume
17
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Subcellular localization and antiviral activity of carminic acid/poly r(A-U) combinations.
Publisher
An entity responsible for making the resource available
Cell biology international
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-10
Subject
The topic of the resource
Antiviral Agents/*pharmacology; Carmine/*analogs & derivatives/pharmacokinetics/pharmacology; Cell Nucleolus/metabolism; Cells; Chromatin/metabolism; Cultured; Doxorubicin/pharmacology; Drug Combinations; Drug Synergism; Fluorescence; Humans; Interferon-beta/biosynthesis/physiology; Microscopy; Phase-Contrast; Poly A-U/*pharmacokinetics/*pharmacology; Vesicular stomatitis Indiana virus/drug effects/growth & development; Viral Plaque Assay
Creator
An entity primarily responsible for making the resource
Krabill K; Jamison J M; Gilloteaux J; Summers J L
Description
An account of the resource
Carminic acid (CAR) enhances the antiviral activity of poly r(A-U) twelve-fold without increasing interferon induction, inactivating the vesicular stomatitis virus or inducing host cell cytotoxicity. Phase contrast photomicrographs of human foreskin fibroblasts (HSF) incubated with CAR alone, poly r(A-U) alone or with a CAR/poly r(A-U) combination illustrate that the CAR/poly r(A-U) combinations display altered subcellular distribution with the CAR being localized in the nucleoli and chromatin. Phase contrast and fluorescence photomicrographs of adriamycin (ADR)-treated and ADR/poly r(A-U)-treated HSF cells corroborate these findings. These results suggest that modulation of one or more nucleolar processes may be responsible for the enhanced antiviral activity.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1006/cbir.1993.1014" target="_blank" rel="noreferrer noopener">10.1006/cbir.1993.1014</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Antiviral Agents/*pharmacology
Carmine/*analogs & derivatives/pharmacokinetics/pharmacology
Cell biology international
Cell Nucleolus/metabolism
Cells
Chromatin/metabolism
Cultured
Doxorubicin/pharmacology
Drug Combinations
Drug Synergism
Fluorescence
Gilloteaux J
Humans
Interferon-beta/biosynthesis/physiology
Jamison J M
Krabill K
Microscopy
Phase-Contrast
Poly A-U/*pharmacokinetics/*pharmacology
Summers J L
Vesicular stomatitis Indiana virus/drug effects/growth & development
Viral Plaque Assay
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1006/cbir.1996.0102" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/cbir.1996.0102</a>
Pages
787–797
Issue
12
Volume
20
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Synergistic antitumour activity of vitamins C and K3 against human prostate carcinoma cell lines.
Publisher
An entity responsible for making the resource available
Cell biology international
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-12
Subject
The topic of the resource
Adenosine Triphosphate/biosynthesis; Antineoplastic Agents/*pharmacology/toxicity; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Ascorbic Acid/*pharmacology/toxicity; Carcinoma/*metabolism; Catalase/pharmacology; Cultured; DNA; Humans; Hydrogen Peroxide/metabolism; Lipid Peroxidation; Male; Neoplasm Proteins/biosynthesis; Neoplasm/biosynthesis; Prostatic Neoplasms/*metabolism; Sulfhydryl Compounds/analysis; Tumor Cells; Vitamin K/*pharmacology/toxicity
Creator
An entity primarily responsible for making the resource
Venugopal M; Jamison J M; Gilloteaux J; Koch J A; Summers M; Hoke J; Sowick C; Summers J L
Description
An account of the resource
Vitamins C, K3 (VC, VK3) and a VC/VK3 combination with a VC:VK3 ratio of 100:1 were assayed for their antitumour activity against two human prostatic carcinoma cell lines. Co-administration of the vitamins enhanced the antitumour activity 5- to 20-fold even with a 1 h exposure time. While exogenous catalase destroyed the antitumour activity, hydrogen peroxide-induced lipid peroxidation was negligible. Analysis of cellular ATP and thiol levels as well as DNA and protein synthesis revealed: a transient increase in ATP production, a decrease in DNA synthesis, an increase in protein synthesis and a decrease in thiol levels. These results suggested that the increased cytotoxicity of the vitamin combination was due to redox cycling and increased oxidative stress.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1006/cbir.1996.0102" target="_blank" rel="noreferrer noopener">10.1006/cbir.1996.0102</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1996
Adenosine Triphosphate/biosynthesis
Antineoplastic Agents/*pharmacology/toxicity
Antineoplastic Combined Chemotherapy Protocols/pharmacology
Ascorbic Acid/*pharmacology/toxicity
Carcinoma/*metabolism
Catalase/pharmacology
Cell biology international
Cultured
Department of Anatomy & Neurobiology
DNA
Gilloteaux J
Hoke J
Humans
Hydrogen Peroxide/metabolism
Jamison J M
Koch J A
Lipid Peroxidation
Male
NEOMED College of Medicine
Neoplasm Proteins/biosynthesis
Neoplasm/biosynthesis
Prostatic Neoplasms/*metabolism
Sowick C
Sulfhydryl Compounds/analysis
Summers J L
Summers M
Tumor Cells
Venugopal M
Vitamin K/*pharmacology/toxicity