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Text
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URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90476-v" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90476-v</a>
Pages
1023–1031
Issue
4
Volume
43
Dublin Core
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Title
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Psychostimulant-induced activity is attenuated by two putative dopamine release inhibitors.
Publisher
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Pharmacology, biochemistry, and behavior
Date
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1992
1992-12
Subject
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Alkaloids/antagonists & inhibitors; Amphetamine/antagonists & inhibitors/pharmacology; Animals; Antipsychotic Agents/pharmacology; Central Nervous System Stimulants/*antagonists & inhibitors/pharmacology; Cocaine/antagonists & inhibitors; Dopamine Antagonists; Dopamine/*physiology; Injections; Intraventricular; Isradipine/pharmacology; Male; Motor Activity/*drug effects; Psychotropic Drugs/pharmacology; Rats; Sprague-Dawley; Thiazepines/pharmacology
Creator
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Calcagnetti D J; Schechter M D
Description
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Centrally administered amphetamine (AMPH), cathinone, (CATH), or cocaine (COC) have each been shown to produce elevated activity in rats and this effect is dose responsive. The question remains whether these psychostimulants share a common mechanism of action (i.e., do these psychostimulants act by releasing dopamine to increase activity levels?). Experiments were, therefore, conducted to measure the spontaneous activity of these three centrally administered psychostimulants in rats following pretreatment with two putative dopamine release inhibitors, viz.,
Identifier
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<a href="http://doi.org/10.1016/0091-3057(92)90476-v" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90476-v</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Alkaloids/antagonists & inhibitors
Amphetamine/antagonists & inhibitors/pharmacology
Animals
Antipsychotic Agents/pharmacology
Calcagnetti D J
Central Nervous System Stimulants/*antagonists & inhibitors/pharmacology
Cocaine/antagonists & inhibitors
Dopamine Antagonists
Dopamine/*physiology
Injections
Intraventricular
Isradipine/pharmacology
Male
Motor Activity/*drug effects
Pharmacology, biochemistry, and behavior
Psychotropic Drugs/pharmacology
Rats
Schechter M D
Sprague-Dawley
Thiazepines/pharmacology