1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0196-9781(01)00638-6" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0196-9781(01)00638-6</a>
Pages
507–514
Issue
3
Volume
23
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Calcitonin gene-related peptide-receptor component protein expression in the uterine cervix, lumbosacral spinal cord, and dorsal root ganglia.
Publisher
An entity responsible for making the resource available
Peptides
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
2002-03
Subject
The topic of the resource
Animals; Calcitonin Gene-Related Peptide/*biosynthesis/immunology/metabolism; Cervix Uteri/*metabolism; Female; Ganglia; Lumbosacral Region; Rats; Receptors; Spinal Cord/*metabolism; Spinal/*metabolism; Sprague-Dawley; Uterus/metabolism
Creator
An entity primarily responsible for making the resource
Pokabla M J; Dickerson I M; Papka R E
Description
An account of the resource
The neuropeptide calcitonin gene-related peptide (CGRP) may play a role in neurogenic inflammation, tissue remodeling of the uterine cervix, promoting vasodilation, parturition, and processing of sensory information in the spinal cord. CGRP-immunoreactive nerves of the cervix and spinal cord have been studied but cellular identification of the CGRP receptor has received little attention.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0196-9781(01)00638-6" target="_blank" rel="noreferrer noopener">10.1016/s0196-9781(01)00638-6</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2002
Animals
Calcitonin Gene-Related Peptide/*biosynthesis/immunology/metabolism
Cervix Uteri/*metabolism
Dickerson I M
Female
Ganglia
Lumbosacral Region
Papka R E
Peptides
Pokabla M J
Rats
Receptors
Spinal Cord/*metabolism
Spinal/*metabolism
Sprague-Dawley
Uterus/metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.peptides.2005.08.005" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.peptides.2005.08.005</a>
Pages
743–752
Issue
4
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Expression of pituitary adenylate cyclase activating peptide in the uterine cervix, lumbosacral dorsal root ganglia and spinal cord of rats during pregnancy.
Publisher
An entity responsible for making the resource available
Peptides
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
2006-04
Subject
The topic of the resource
*Gene Expression Regulation; Animals; Cervix Uteri/*metabolism; Female; Ganglia; Messenger; Pituitary Adenylate Cyclase-Activating Polypeptide/*genetics/*metabolism; Pregnancy; Rats; RNA; Spinal Cord/*metabolism; Spinal/*metabolism; Time Factors
Creator
An entity primarily responsible for making the resource
Papka R E; Workley M; Usip S; Mowa C N; Fahrenkrug J
Description
An account of the resource
The uterine cervix is highly innervated by the sensory nerves containing neuropeptides which change during pregnancy and are regulated, in part, by estrogen. These neuropeptides act as transmitters both in the spinal cord and cervix. The present study was undertaken to determine the expression pattern of the neuropeptide pituitary adenylate cyclase activating peptide (PACAP) in the cervix and its nerves during pregnancy and the influence of estrogen on this expression using immunohistochemistry, radioimmunoassay and RT-PCR. PACAP immunoreactivity was detected in nerves in the cervix, lumbosacral (L6-S1) dorsal root ganglia (DRG) and spinal cord. PACAP immunoreactivity was highest at day 15 of pregnancy in the cervix and dorsal spinal cord, but then decreased over the last trimester of pregnancy. However, levels of PACAP mRNA increased in the L6-S1 DRG at late pregnancy relative to early pregnancy. DRG of ovariectomized rats treated with estrogen showed increased PACAP mRNA synthesis in a dose-related manner, an effect partially blocked by the estrogen receptor (ER) antagonist ICI 182,780. We postulate that synthesis of PACAP in L6-S1 DRG and utilization in the cervix and spinal cord increase over pregnancy and this synthesis is the under influence of the estrogen-ER system. Since PACAP is expressed by sensory nerves and may have roles in nociception and vascular function, collectively, these data are consistent with the hypothesis that sensory nerve-derived neuronal factors innervate the cervix and play a role in cervical ripening.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.peptides.2005.08.005" target="_blank" rel="noreferrer noopener">10.1016/j.peptides.2005.08.005</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Gene Expression Regulation
2006
Animals
Cervix Uteri/*metabolism
Department of Anatomy & Neurobiology
Fahrenkrug J
Female
Ganglia
Messenger
Mowa C N
NEOMED College of Medicine
Papka R E
Peptides
Pituitary Adenylate Cyclase-Activating Polypeptide/*genetics/*metabolism
Pregnancy
Rats
RNA
Spinal Cord/*metabolism
Spinal/*metabolism
Time Factors
Usip S
Workley M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00441-005-1114-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00441-005-1114-8</a>
Pages
35–44
Issue
1
Volume
321
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy.
Publisher
An entity responsible for making the resource available
Cell and tissue research
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005-07
Subject
The topic of the resource
Animals; Blotting; Cervix Uteri/*metabolism; Estrogen Receptor alpha/metabolism; Female; Frozen Sections; Ganglia; Immunohistochemistry; Lumbosacral Region; Pregnancy; Purinergic P2/*metabolism; Purinergic P2X; Rats; Receptors; Spinal Cord/cytology/*metabolism; Spinal/cytology/*metabolism; Sprague-Dawley; Western
Creator
An entity primarily responsible for making the resource
Papka Raymond E; Hafemeister Jen; Storey-Workley Megan
Description
An account of the resource
ATP, an intracellular energy source, is released from cells during tissue stress, damage, or inflammation. The P2X subtype of the ATP receptor is expressed in rat dorsal root ganglion (DRG) cells, spinal cord dorsal horn, and axons in peripheral tissues. ATP binding to P2X receptors on nociceptors generates signals that can be interpreted as pain from damaged tissue. We have hypothesized that tissue stress or damage in the uterine cervix during late pregnancy and parturition can lead to ATP release and sensory signaling via P2X receptors. Consequently, we have examined sensory pathways from the cervix in nonpregnant and pregnant rats for the presence of purinoceptors. Antiserum against the
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00441-005-1114-8" target="_blank" rel="noreferrer noopener">10.1007/s00441-005-1114-8</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2005
Animals
Blotting
Cell and tissue research
Cervix Uteri/*metabolism
Estrogen Receptor alpha/metabolism
Female
Frozen Sections
Ganglia
Hafemeister Jen
Immunohistochemistry
Lumbosacral Region
Papka Raymond E
Pregnancy
Purinergic P2/*metabolism
Purinergic P2X
Rats
Receptors
Spinal Cord/cytology/*metabolism
Spinal/cytology/*metabolism
Sprague-Dawley
Storey-Workley Megan
Western