1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(91)90010-y" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(91)90010-y</a>
Pages
539–544
Issue
3
Volume
38
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effect of MDMA neurotoxicity upon its conditioned place preference and discrimination.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-03
Subject
The topic of the resource
Male; Animals; Rats; Discrimination Learning/*drug effects; Choice Behavior/*drug effects; Designer Drugs/*toxicity; Nervous System/*drug effects; Sodium Chloride/pharmacology; Dose-Response Relationship; Drug; Inbred Strains; 3; Conditioning; Classical/*drug effects; N-Methyl-3; 4-methylenedioxyamphetamine; 4-Methylenedioxyamphetamine/*analogs & derivatives/toxicity
Creator
An entity primarily responsible for making the resource
Schechter M D
Description
An account of the resource
Experiments were conducted to investigate the functional consequences of a neurotoxic regimen of MDMA administration upon two behaviors, conditioned place preference and drug discrimination. Rats were trained to discriminate 1.5 mg/kg MDMA from its vehicle and their discriminative performance was shown to be dose-responsive. Subsequently, MDMA was observed to produce a conditioned place preference as three conditioning sessions with 1.5 mg/kg MDMA paired with the nonpreferred chamber increased the time the rats spent in the chamber paired with MDMA. Administration of a proportedly neurotoxic dose (20 mg/kg subcutaneous) of MDMA, twice-a-day for four days, did not affect this conditioned place preference when it was redetermined at a time of maximal neurochemical compromise. In contrast, sensitivity to 1.0 mg/kg MDMA in the drug discrimination task was shown to be significantly decreased after the neurotoxic regimen. Results are discussed in light of MDMA effects upon both central serotonergic and dopaminergic neurons.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(91)90010-y" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(91)90010-y</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1991
3
4-methylenedioxyamphetamine
4-Methylenedioxyamphetamine/*analogs & derivatives/toxicity
Animals
Choice Behavior/*drug effects
Classical/*drug effects
Conditioning
Designer Drugs/*toxicity
Discrimination Learning/*drug effects
Dose-Response Relationship
Drug
Inbred Strains
Male
N-Methyl-3
Nervous System/*drug effects
Pharmacology, biochemistry, and behavior
Rats
Schechter M D
Sodium Chloride/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0091-3057(97)00391-2" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0091-3057(97)00391-2</a>
Pages
105–108
Issue
1
Volume
59
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
LSD produces conditioned place preference in male but not female fawn hooded rats.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-01
Subject
The topic of the resource
*Cues; *Sex Characteristics; Analysis of Variance; Animals; Choice Behavior/*drug effects; Conditioning; Female; Humans; Inbred Strains; Lysergic Acid Diethylamide/*pharmacology; Male; Operant/*drug effects; Rats
Creator
An entity primarily responsible for making the resource
Meehan S M; Schechter M D
Description
An account of the resource
Male and female Fawn Hooded rats were examined for conditioned place preference (CPP) or aversion (CPA) to lysergic acid diethylamide (LSD). Using a biased design, experimental animals were trained with LSD (0.2 mg/kg, I.P.) administered in conjunction with confinement in either the preferred or nonpreferred location. Control animals received confinement in both locations after administration of saline. Results indicated that rats administered LSD while sequestered in the nonpreferred location spent more time in that location during a nondrug test. This effect, indicative of a conditioned place preference, was exhibited only in male animals. Results are discussed in terms of potential sex differences that may mediate serotonergic sensitivity in the Fawn Hooded rat strain.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0091-3057(97)00391-2" target="_blank" rel="noreferrer noopener">10.1016/s0091-3057(97)00391-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Cues
*Sex Characteristics
1998
Analysis of Variance
Animals
Choice Behavior/*drug effects
Conditioning
Female
Humans
Inbred Strains
Lysergic Acid Diethylamide/*pharmacology
Male
Meehan S M
Operant/*drug effects
Pharmacology, biochemistry, and behavior
Rats
Schechter M D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90475-u" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90475-u</a>
Pages
1015–1021
Issue
4
Volume
43
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Rats bred for differences in preference to cocaine: other behavioral measurements.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-12
Subject
The topic of the resource
Animal/*drug effects; Animals; Behavior; Choice Behavior/*drug effects; Cocaine/*pharmacology; Dose-Response Relationship; Drug; Female; Inbred Strains; Male; Motor Activity/drug effects; Rats; Species Specificity; Sprague-Dawley
Creator
An entity primarily responsible for making the resource
Schechter M D
Description
An account of the resource
Cocaine has repeatedly been shown to produce conditioned place preference (CPP) in the rat. The present study employed the heterogenous N/Nih rat stock to produce a selectively bred rat line determined by individual place preference to a conditioning dose of 2.5 mg/kg cocaine. As each of three generations of rats were exposed to the CPP task, cocaine-preferring (CP) males were mated with CP females whereas cocaine-nonpreferring (CNP) male rats were paired with their female counterparts. Rats in litters of the third generation of these selectively bred rats were used in two collateral studies: one involving the discriminative stimulus properties of cocaine and the other to investigate the ability of cocaine to stimulate activity. Results indicate that the continued breeding of CP animals has resulted in rats that prefer cocaine, whereas the breeding of CNP rats is defining a line of rats that actually find cocaine aversive. In testing the discriminative stimulus performance of five male CP and five male CNP rats, the learning rates and dose-response relationship to cocaine were not significantly different between these two groups. In contrast, administration of 5.0 and 7.5 mg/kg cocaine to male and female CP and CNP rats indicated that, although all groups were stimulated by cocaine when compared to vehicle administration, male CNP rats showed a significantly decreased reaction to these two doses of cocaine. The possibility that conditioned place preference and locomotor stimulation are subserved by the same neural substrates, that is, most probably the dopaminergic systems in the nucleus accumbens of the brain, is discussed.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(92)90475-u" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90475-u</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Animal/*drug effects
Animals
Behavior
Choice Behavior/*drug effects
Cocaine/*pharmacology
Dose-Response Relationship
Drug
Female
Inbred Strains
Male
Motor Activity/drug effects
Pharmacology, biochemistry, and behavior
Rats
Schechter M D
Species Specificity
Sprague-Dawley
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0278-5846(92)90114-t" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0278-5846(92)90114-t</a>
Pages
969–976
Issue
6
Volume
16
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Reducing the time needed to conduct conditioned place preference testing.
Publisher
An entity responsible for making the resource available
Progress in neuro-psychopharmacology & biological psychiatry
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1905-06
Subject
The topic of the resource
Alkaloids/pharmacology; Animals; Choice Behavior/*drug effects; Conditioning; Experimental/instrumentation/methods; Inbred Strains; Male; Motor Activity/drug effects; Operant/*drug effects; Psychology; Psychotropic Drugs/pharmacology; Rats
Creator
An entity primarily responsible for making the resource
Calcagnetti D J; Schechter M D
Description
An account of the resource
The objective of the present experiment was to demonstrate whether four days of twice-a-day conditioned place conditioning produces a preference that is equivalent to that produced by using eight days of once-a-day training. Two doses of the amphetamine-like stimulant drug cathinone (0.2 and 1.6 mg/kg) were selected to demonstrate the effectiveness of twice-a-day (morning-vehicle; afternoon-drug pairings) conditioning. The 0.2 mg/kg dose of cathinone failed to affect the expression of place preference, whereas the 1.6 mg/kg dose produced a significant (p less than 0.002) shift in CPP from baseline when compared to previous measurements. These results demonstrate that twice-a-day pairings over four days effectively shorten the total duration of training without changing the development of place preference produced by once-a-day over eight conditioning day schedule.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0278-5846(92)90114-t" target="_blank" rel="noreferrer noopener">10.1016/0278-5846(92)90114-t</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Alkaloids/pharmacology
Animals
Calcagnetti D J
Choice Behavior/*drug effects
Conditioning
Experimental/instrumentation/methods
Inbred Strains
Male
Motor Activity/drug effects
Operant/*drug effects
Progress in neuro-psychopharmacology & biological psychiatry
Psychology
Psychotropic Drugs/pharmacology
Rats
Schechter M D