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Text
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URL Address
<a href="http://doi.org/10.1016/0014-2999(93)90739-5" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0014-2999(93)90739-5</a>
Pages
135–138
Issue
1
Volume
232
Dublin Core
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Title
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Conditioned place preference produced by the psychostimulant cathinone.
Publisher
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European journal of pharmacology
Date
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1993
1993-02
Subject
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Alkaloids/administration & dosage/*pharmacology; Animals; Central Nervous System Stimulants/administration & dosage/*pharmacology; Choice Behavior/drug effects; Conditioning (Psychology)/drug effects; Dose-Response Relationship; Drug; Habituation; Male; Motor Activity/*drug effects; Psychophysiologic; Rats; Sprague-Dawley
Creator
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Schechter M D; Meehan S M
Description
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Previous work has indicated that the psychostimulant cathinone produces a location preference in the conditioned place preference task. The present study expanded upon this earlier work by examining the dose-response nature of cathinone-induced conditioned place preference, as well as testing its effect upon spontaneous locomotor activity. At doses ranging from 0.2 to 1.6 mg/kg, cathinone produced a conditioned place preference at all but the lowest dose, and the highest dose but not the lowest dose increased locomotor activity. Results are discussed in terms of dopaminergic mediation of conditioned place preference and the relationship between conditioned place preference and locomotion being subserved by the same neuronal system.
Identifier
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<a href="http://doi.org/10.1016/0014-2999(93)90739-5" target="_blank" rel="noreferrer noopener">10.1016/0014-2999(93)90739-5</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Alkaloids/administration & dosage/*pharmacology
Animals
Central Nervous System Stimulants/administration & dosage/*pharmacology
Choice Behavior/drug effects
Conditioning (Psychology)/drug effects
Dose-Response Relationship
Drug
European journal of pharmacology
Habituation
Male
Meehan S M
Motor Activity/*drug effects
Psychophysiologic
Rats
Schechter M D
Sprague-Dawley