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Text
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URL Address
<a href="http://doi.org/10.1055/s-0039-1696641" target="_blank" rel="noreferrer noopener">http://doi.org/10.1055/s-0039-1696641</a>
Pages
357-364
Issue
4
Volume
37
ISSN
1098-8785 0735-1631 0735-1631
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Update Year & Number
Hospital List
Dublin Core
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Title
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Association Between Features of Spontaneous Late Preterm Labor and Late Preterm Birth.
Publisher
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American Journal of Perinatology
Date
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2020
2020-03
Subject
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Humans; Pregnancy; Female; Risk Factors; Logistic Models; Infant Newborn; Sensitivity and Specificity; Prognosis; Gestational Age; Premature Birth; Glucocorticoids/administration & dosage; Pregnancy Trimester Third; Labor Stage First; Obstetric Labor Premature; Betamethasone/administration & dosage; Cervix Uteri; Parity; Respiratory Tract Diseases/prevention & control
Creator
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Glover AV; Battarbee AN; Gyamfi-Bannerman C; Boggess KA; Sandoval G; Blackwell SC; Tita ATN; Reddy UM; Jain L; Saade GR; Rouse DJ; Iams JD; Clark EAS; Chien EK; Peaceman AM; Gibbs RS; Swamy GK; Norton ME; Casey BM; Caritis SN; Tolosa JE; Sorokin Y; Manuck TA
Description
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OBJECTIVE: This study aimed to evaluate the association between clinical and examination features at admission and late preterm birth. STUDY DESIGN: The present study is a secondary analysis of a randomized trial of singleton pregnancies at 34(0/7) to 36(5/7) weeks' gestation. We included women in spontaneous preterm labor with intact membranes and compared them by gestational age at delivery (preterm vs. term). We calculated a statistical cut-point optimizing the sensitivity and specificity of initial cervical dilation and effacement at predicting preterm birth and used multivariable regression to identify factors associated with late preterm delivery. RESULTS: A total of 431 out of 732 (59%) women delivered preterm. Cervical dilation ≥ 4 cm was 60% sensitive and 68% specific for late preterm birth. Cervical effacement ≥ 75% was 59% sensitive and 65% specific for late preterm birth. Earlier gestational age at randomization, nulliparity, and fetal malpresentation were associated with late preterm birth. The final regression model including clinical and examination features significantly improved late preterm birth prediction (81% sensitivity, 48% specificity, area under the curve = 0.72, 95% confidence interval [CI]: 0.68-0.75, and p-value < 0.01). CONCLUSION: Four in 10 women in late-preterm labor subsequently delivered at term. Combination of examination and clinical features (including parity and gestational age) improved late-preterm birth prediction.
Identifier
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<a href="http://doi.org/10.1055/s-0039-1696641" target="_blank" rel="noreferrer noopener">10.1055/s-0039-1696641</a>
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journalArticle
2020
American Journal of Perinatology
Battarbee AN
Betamethasone/administration & dosage
Blackwell SC
Boggess KA
Caritis SN
Casey BM
Cervix Uteri
Chien EK
Clark EAS
Female
Gestational Age
Gibbs RS
Glover AV
Glucocorticoids/administration & dosage
Gyamfi-Bannerman C
Hospital List
Humans
Iams JD
Infant Newborn
Jain L
journalArticle
Labor Stage First
Logistic Models
Manuck TA
Norton ME
Obstetric Labor Premature
Parity
Peaceman AM
Pregnancy
Pregnancy Trimester Third
Premature Birth
Prognosis
Reddy UM
Respiratory Tract Diseases/prevention & control
Risk Factors
Rouse DJ
Saade GR
Sandoval G
Sensitivity and Specificity
Sorokin Y
Swamy GK
Tita ATN
Tolosa JE