1
40
5
-
Text
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URL Address
<a href="http://doi.org/10.2146/ajhp100274" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/ajhp100274</a>
Pages
420–423
Issue
5
Volume
68
Dublin Core
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Title
A name given to the resource
Stability of an extemporaneous alcohol-free melatonin suspension.
Publisher
An entity responsible for making the resource available
American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011
Subject
The topic of the resource
Drug Stability; Descriptive Statistics; Administration; Oral; Drug Compounding; Melatonin; Suspensions; Taste
Creator
An entity primarily responsible for making the resource
Johnson Cary E; Cober Mary Petrea; Thome Tennille; Rouse Emily
Description
An account of the resource
Purpose. The stability of alcohol-free oral suspensions of melatonin 1 mg/mL, extemporaneously prepared from two commercially available melatonin tablet products, was studied. Methods. Four 1-mg/mL melatonin suspensions were prepared. Formulations A and B contained 20 crushed 3-mg tablets of melatonin combined with a 1:1 mixture of Ora-Plus and either Ora-Sweet or Ora-Sweet SF to produce a volume of 60 mL. Formulations C and D were prepared by crushing 20 combination tablets containing melatonin 3 mg and pyridoxine hydrochloride 10 mg and then combining the powder with a 1:1 mixture of Ora-Plus and either Ora-Sweet or Ora-Sweet SF to produce a 60-mL volume. The suspensions were prepared in triplicate and stored at room temperature in amber plastic prescription bottles. Immediately after preparation and on days 7, 15, 30, 60, and 90, the samples were assayed in duplicate by stability-indicating high-performance liquid chromatography (HPLC). The samples were also evaluated for any changes in color, odor, and taste. Results. HPLC analysis demonstrated that at least 94% of the initial melatonin concentration in formulations A and B, and at least 98% of that in formulations C and D, remained throughout the 90-day study period. Detectable changes in color, odor, or taste occurred in all of the formulations. Conclusion. Extemporaneously prepared, alcohol-free, 1-mg/mL suspensions of melatonin and melatonin-pyridoxine hydrochloride in a 1:1 mixture of Ora- Plus and either Ora Sweet or Ora Sweet SF were stable for at least 90 days when stored in 2-oz amber plastic bottles at room temperature.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.2146/ajhp100274" target="_blank" rel="noreferrer noopener">10.2146/ajhp100274</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
Administration
American Journal of Health-System Pharmacy
Cober Mary Petrea
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Descriptive Statistics
Drug Compounding
Drug Stability
Johnson Cary E
Melatonin
NEOMED College of Pharmacy
Oral
Rouse Emily
Suspensions
Taste
Thome Tennille
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2146/ajhp100225" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/ajhp100225</a>
Pages
519–521
Issue
6
Volume
68
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Stability of extemporaneously prepared oxandrolone oral suspensions.
Publisher
An entity responsible for making the resource available
American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-03-15
Subject
The topic of the resource
Human; Descriptive Statistics; Administration; Oral; Drug Compounding; Suspensions; Acid-Base Equilibrium; Androgens – Administration and Dosage; Weight Gain – Chemically Induced
Creator
An entity primarily responsible for making the resource
Johnson Cary E; Cober Mary Petrea; Hawkins Katherine A; Julian Justin D
Description
An account of the resource
Purpose. The stability of extemporaneously prepared oxandrolone oral suspensions was studied. Methods. Oxandrolone oral suspension (1 mg/mL) was prepared using oxandrolone tablets, Ora-Plus, and either Ora-Sweet or Ora-Sweet SF. Three identical samples of each formulation were prepared and stored in 2-oz amber plastic bottles with child-resistant caps at room temperature (23-25 °C). After thorough but gentle shaking by hand to prevent foaming, a 1-mL sample was withdrawn from each of the six bottles, diluted with mobile phase to an expected concentration of 200 µg/mL, and assayed in duplicate by injecting 5 µL into the high-performance liquid chromatography system immediately after preparation and at 7, 14, 35, 60, and 90 days. The samples were examined for any change in color or pH on each day of analysis. The stability of the suspensions was determined by calculating the percentage of the initial oxandrolone concentration remaining on each test day. Stability was defined as the retention of at least 90% of the initial oxandrolone concentration. Results. At least 98% of the original oxandrolone concentration remained in both formulations at the end of the 90-day study period. There was no appreciable change in odor, taste, color, or pH. Both suspensions remained white in color and sweet with no aftertaste throughout the study period. The oxandrolone was easily resuspended with gentle shaking. Conclusion. Extemporaneously prepared suspensions of oxandrolone 1 mg/mL in 1:1 mixtures of Ora-Plus and either Ora-Sweet or Ora-Sweet SF were stable for at least 90 days when stored in 2-oz amber plastic bottles at room temperature.
Identifier
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<a href="http://doi.org/10.2146/ajhp100225" target="_blank" rel="noreferrer noopener">10.2146/ajhp100225</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
Acid-Base Equilibrium
Administration
American Journal of Health-System Pharmacy
Androgens – Administration and Dosage
Cober Mary Petrea
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Descriptive Statistics
Drug Compounding
Hawkins Katherine A
Human
Johnson Cary E
Julian Justin D
NEOMED College of Pharmacy
Oral
Suspensions
Weight Gain – Chemically Induced
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/ajhp/zxz174</a>
Pages
1492-1510
Issue
19
Volume
76
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Dublin Core
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Title
A name given to the resource
Enteral and parenteral nutrition considerations in pediatric patients
Publisher
An entity responsible for making the resource available
American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-09
Subject
The topic of the resource
compounding; enteral; neonatal; nutrition; parenteral; pediatric; stability
October 2019 Update
Creator
An entity primarily responsible for making the resource
Cober Mary Petrea; Gura Kathleen M
Description
An account of the resource
PURPOSE: Current clinical practice guidelines on management of enteral nutrition (EN) and parenteral nutrition (PN) in pediatric patients are reviewed. SUMMARY: The provision of EN and PN in pediatric patients poses many unique considerations and challenges. Although indications for use of EN and PN are similar in adult and pediatric populations, recommended EN and PN practices differ for pediatric versus adult patients in areas such as selection of EN and PN formulations, timing of EN and PN initiation, advancement of nutrition support, and EN and PN goals. Additionally, provision of EN and PN to pediatric patients poses unique compounding and medication administration challenges. This article provides a review of current EN and PN best practices and special nutrition considerations for neonates, infants, and other pediatric patients. CONCLUSION: The provision of EN and PN to pediatric patients presents many unique challenges. It is important for pharmacists to keep current with pediatric- and neonatal-specific guidelines on nutritional management of various disease states, as well as strategies to address compounding and medication administration challenges, in order to optimize EN and PN outcomes.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">10.1093/ajhp/zxz174</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2019
American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Cober Mary Petrea
compounding
Department of Pharmacy Practice
enteral
Gura Kathleen M
NEOMED College of Pharmacy
Neonatal
nutrition
October 2019 Update
Parenteral
Pediatric
Stability
-
Text
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URL Address
<a href="http://doi.org/10.1177/1078155220914349" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/1078155220914349</a>
Pages
1078155220914349
ISSN
1477-092X 1078-1552
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1177/1078155220914349" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1177/1078155220914349</a>
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Update Year & Number
June 2020 Update I
NEOMED College
NEOMED College of Pharmacy
NEOMED Department
Department of Pharmacy Practice
Affiliated Hospital
Akron Children's Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Stability of extemporaneously compounded temozolomide 10 mg/mL suspensions in Oral Mix SF(R) in glass and plastic bottles and plastic syringes.
Publisher
An entity responsible for making the resource available
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-03-30
Subject
The topic of the resource
drug stability; suspension; temozolomide
Creator
An entity primarily responsible for making the resource
Lingertat-Walsh Karen; Weilnau JoEllen; Cober Mary Petrea; Ostrenga Andrew; Poon Betsy; Pacita Sales; Law Shirley; Dupuis L Lee; Walker Scott E
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/1078155220914349" target="_blank" rel="noreferrer noopener">10.1177/1078155220914349</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
Akron Children's Hospital
Cober Mary Petrea
Department of Pharmacy Practice
Drug Stability
Dupuis L Lee
Journal Article
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
journalArticle
June 2020 Update I
Law Shirley
Lingertat-Walsh Karen
NEOMED College of Pharmacy
Ostrenga Andrew
Pacita Sales
Poon Betsy
suspension
temozolomide
Walker Scott E
Weilnau JoEllen
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/jcpt.13138" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/jcpt.13138</a>
ISSN
1365-2710 0269-4727
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Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1111/jcpt.13138" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1111/jcpt.13138</a>
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Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Pharmacy
NEOMED Department
Department of Pharmacy Practice
Affiliated Hospital
Akron Children's Hospital
Dublin Core
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Title
A name given to the resource
Letter to the editor regarding dosing accuracy of female low dose syringes.
Publisher
An entity responsible for making the resource available
Journal of clinical pharmacy and therapeutics
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-04-07
Creator
An entity primarily responsible for making the resource
Lyman Beth; Cober Mary Petrea
Identifier
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<a href="http://doi.org/10.1111/jcpt.13138" target="_blank" rel="noreferrer noopener">10.1111/jcpt.13138</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
Akron Children's Hospital
Cober Mary Petrea
Department of Pharmacy Practice
Journal of Clinical Pharmacy and Therapeutics
journalArticle
June 2020 Update II
Lyman Beth
NEOMED College of Pharmacy