1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/ICO.0b013e3181ee67fd" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/ICO.0b013e3181ee67fd</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
360-363
Issue
3
Volume
30
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Copper Deposition In A Variant Of Multiple Myeloma: Pathologic Changes In The Cornea And The Lens Capsule
Publisher
An entity responsible for making the resource available
Cornea
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-03
Subject
The topic of the resource
central defect; copper deposition; deposition; Descemet membrane; descemets membrane; hypercupremia; immunoglobulin; leukomas; monoclonal gammopathy; multiple myeloma; ocular; Ophthalmology; true exfoliation; wilsons-disease
Creator
An entity primarily responsible for making the resource
Edward D P; Patil A J; Sugar J; Parikh M
Identifier
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<a href="http://doi.org/10.1097/ICO.0b013e3181ee67fd" target="_blank" rel="noreferrer noopener">10.1097/ICO.0b013e3181ee67fd</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2011
central defect
copper deposition
Cornea
deposition
Descemet membrane
descemets membrane
Edward D P
hypercupremia
immunoglobulin
leukomas
monoclonal gammopathy
multiple myeloma
ocular
Ophthalmology
Parikh M
Patil A J
Sugar J
true exfoliation
wilsons-disease
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.exer.2020.108257" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.exer.2020.108257</a>
Pages
108257
Volume
201
ISSN
1096-0007
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1016/j.exer.2020.108257" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1016/j.exer.2020.108257</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
September 2020 List
NEOMED College
NEOMED College of Medicine Student
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Department of Integrative Medical Sciences
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The role of TRPV4 channels in ocular function and pathologies.
Publisher
An entity responsible for making the resource available
Experimental Eye Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-09-29
Subject
The topic of the resource
Glaucoma; TRPV4; Angiogenesis; Retina; Calcium channel; Cornea; Diabetic retinopathy; Lens; Osmolarity
Creator
An entity primarily responsible for making the resource
Guarino BD;Paruchuri S;Thodeti CK
Description
An account of the resource
Transient potential receptor vanilloid 4 (TRPV4) is an ion channel responsible for sensing osmotic and mechanical signals, which in turn regulates calcium signaling across cell membranes. TRPV4 is widely expressed throughout the body, and plays an important role in normal physiological function, as well as different pathologies, however, its role in the eye is not well known. In the eye, TRPV4 is expressed in various tissues, such as the retina, corneal epithelium, ciliary body, and the lens. In this review, we provide an overview on TRPV4 structure, activation, mutations, and summarize the current knowledge of TRPV4 function and signaling mechanisms in various locations throughout the eye, as well as its role in ocular diseases, such as glaucoma and diabetic retinopathy. Based on the available data, we highlight the therapeutic potential of TRPV4 as well as the shortcomings of current research. Finally, we provide future perspectives on the implications of targeting TRPV4 to treat various ocular pathologies. (Copyright © 2020 Elsevier Ltd. All rights reserved.)
Identifier
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<a href="http://doi.org/10.1016/j.exer.2020.108257" target="_blank" rel="noreferrer noopener">10.1016/j.exer.2020.108257</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
angiogenesis
calcium channel
Cornea
Department of Integrative Medical Sciences
diabetic retinopathy
Experimental eye research
Glaucoma
Guarino BD
journalArticle
Lens
NEOMED College of Medicine
NEOMED College of Medicine Student
NEOMED Student Publications
Osmolarity
Paruchuri S
retina
September 2020 List
Thodeti CK
TRPV4