Dermatoepidemiology
evidence-based medicine; Dermatology; Dermatology; health-care; clinical-trials; malignancy; malignant-melanoma; randomized controlled-trials; internal; skin-cancer; consort statement; cutaneous; disseminating systematic reviews; evidence-based
Barzilai D A; Freiman A; Dellavalle R P; Weinstock M A; Mostow E N
Journal of the American Academy of Dermatology
2005
2005-04
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/j.jaad.2004.09.019" target="_blank" rel="noreferrer noopener">10.1016/j.jaad.2004.09.019</a>
Reversible ectropion after long-term use of topical tretinoin on photodamaged skin.
Administration; Aged; Cutaneous; Ectropion/*chemically induced; Face; Female; Humans; Middle Aged; Skin Aging/*drug effects; Tretinoin/administration & dosage/*adverse effects
Brodell L P; Asselin D; Brodell R T
Journal of the American Academy of Dermatology
1992
1992-10
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1016/s0190-9622(08)80199-5" target="_blank" rel="noreferrer noopener">10.1016/s0190-9622(08)80199-5</a>
Topical corticosteroid-induced acne. Three treatment strategies to break the 'addiction' cycle.
Female; Humans; Child; Anti-Infective Agents; Glucocorticoids; Anti-Inflammatory Agents/*adverse effects; Acne Vulgaris/*chemically induced; Anti-Bacterial Agents/administration & dosage/therapeutic use; Betamethasone/adverse effects; Clindamycin/administration & dosage/therapeutic use; Clotrimazole/adverse effects; Desonide/adverse effects; Erythema/chemically induced; Erythromycin Ethylsuccinate/administration & dosage/therapeutic use; Facial Dermatoses/*chemically induced; Preschool; Administration; Oral; Cutaneous; Local/adverse effects
Brodell R T; O'Brien M J Jr
Postgraduate medicine
1999
1999-11
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.3810/pgm.1999.11.796" target="_blank" rel="noreferrer noopener">10.3810/pgm.1999.11.796</a>
Overview of the treatment of acne vulgaris with topical retinoids.
Humans; Severity of Illness Index; Primary Health Care; Acne Vulgaris/*drug therapy/physiopathology; Retinoids/administration & dosage/adverse effects/*therapeutic use; Administration; Cutaneous
Acne vulgaris is a common skin disease that is most effectively treated with a combination of topical products and, in some cases, systemic antibiotics. While it is important to treat papules, pustules, nodules, and cysts with topical or systemic antibiotics to suppress bacterial infection, all of these lesions develop from microcomedones. In fact, comedolytic agents enhance the effectiveness of antibiotics and limit the potential for recurrent acne lesions. Because of the superior comedolytic effects of topical retinoids, most patients with acne should be treated with a retinoid unless there is a specific contraindication. Interestingly, only 55% of patients with acne who are treated by dermatologists and 10% of patients with acne who are treated by primary care physicians receive a topical retinoid as a component of their acne regimen. Evidence is provided to buttress the contention that clinical outcomes will be improved if topical retinoids are utilized in patients with acne vulgaris.
Hsu Peter; Litman George I; Brodell Robert T
Postgraduate medicine
2011
2011-05
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.3810/pgm.2011.05.2294" target="_blank" rel="noreferrer noopener">10.3810/pgm.2011.05.2294</a>
Cutaneous involvement in a case of multifocal idiopathic fibrosclerosis.
cutaneous; fibrosclerosis; IgG4; MIF multifocal idiopathic fibrosclerosis; multifocal idiopathic; retroperitoneal fibrosis
Kromer Courtney; Winfield Harry; Franklin Matthew
JAAD case reports
2020
2020-04
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.1016/j.jdcr.2020.02.020" target="_blank" rel="noreferrer noopener">10.1016/j.jdcr.2020.02.020</a>
Crusted (Norwegian) scabies. A simple office test demystifies the 'great imitator'.
Female; Humans; Aged; Anti-Inflammatory Agents/adverse effects; Coloring Agents; Insecticides/therapeutic use; Office Visits; Permethrin; Pyrethrins/therapeutic use; Scabies/*diagnosis/drug therapy; Steroids; Diagnosis; Differential; Administration; Cutaneous
Nowak M A; Mirando W S; Brodell R T
Postgraduate medicine
1999
1999-05
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.3810/pgm.1999.05.1.762" target="_blank" rel="noreferrer noopener">10.3810/pgm.1999.05.1.762</a>
Managing psoriasis: what's best for your patient?
Humans; Male; Middle Aged; Adrenal Cortex Hormones/therapeutic use; Immunosuppressive Agents/therapeutic use; Ultraviolet Therapy; Combined Modality Therapy; *Patient Compliance; Anti-Inflammatory Agents/therapeutic use; Dermatologic Agents/therapeutic use; Photochemotherapy; Psoriasis/drug therapy/radiotherapy/*therapy; Administration; Cutaneous; ANTISEPTICS; DRUG side effects; PHOTOTHERAPY; PSORIASIS treatment; QUALITY of life; SKIN disease treatment
Whether the symptoms are mild, moderate, or severe, the optimal treatment plan is the one the patient is most likely to follow.
Uhlenhake Elizabeth E; Mehregan David A
The Journal of Family Practice
2012
2012-07
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.
Humans; Male; Animals; Mice; Cell Differentiation; Wound Healing/*physiology; Macrophages/*physiology; Diabetes Mellitus; Cells; Cultured; Inbred C57BL; Animal; Disease Models; Administration; Cutaneous; Cell Communication/*physiology; Eye Proteins/administration & dosage/genetics/*physiology; Membrane Glycoproteins/administration & dosage/genetics/*physiology; Mesenchymal Stem Cells/*physiology; Recombinant Proteins/administration & dosage/genetics/metabolism; Skin/*injuries/metabolism; Type 2/complications/pathology
The process of wound repair requires the coordinated participation of multiple types of cells, which are sequentially recruited during the healing process. In response to tissue injury, both macrophages and mesenchymal stem cells (MSCs) are recruited to the site of injury, where they participate in the repair process. Despite considerable understanding of the role of each cell type in the process of wound repair, the nature of the dynamic interplay between these two cell types and how this interaction influences the process of wound repair are not well understood. Here, using an in vivo model of cutaneous wound healing in mice, we provide evidence that GPNMB is functionally important in promoting the recruitment of MSCs to the site of skin injury, which in turn modulates inflammatory responses by directing the M2 polarization of macrophages in acute wound healing. Furthermore, we show that GPNMB activity is impaired in a diabetic wound environment, which is associated with impaired MSC recruitment that is reversed by the topical administration of recombinant GPNMB protein to the wounds of diabetic mice. Our study provides important insight into the crosstalk between macrophages and endogenous MSCs toward wound repair.
Yu Bing; Alboslemy Talib; Safadi Fayez; Kim Min-Ho
The Journal of investigative dermatology
2018
2018-01
<a href="http://doi.org/10.1016/j.jid.2017.08.034" target="_blank" rel="noreferrer noopener">10.1016/j.jid.2017.08.034</a>