Browse Items (328 total)
- Tags: Department of Integrative Medical Sciences
4-Hydroxynonenal dependent alteration of TRPV1-mediated coronary microvascular signaling.
Tags: *4-Hydroxynonenal, *Coronary regulation, *Lipid peroxidation, *Post-translational modification, *Protein Processing, *Reactive oxygen species, *Signal Transduction, *TRPV1, 2016, Action Potentials/drug effects, Aldehydes/antagonists & inhibitors/metabolism/*pharmacology, Animal, Animals, Blood Flow Velocity, Bratz Ian N, Calcium Signaling/drug effects, Cappelli Holly C, Capsaicin/*pharmacology, Cardiovascular Agents/*pharmacology, Connell Patrick J, Coronary Circulation/drug effects, Coronary Vessels/metabolism/physiopathology, Cysteine/genetics/metabolism, Damron Derek S, DelloStritto Daniel J, Department of Integrative Medical Sciences, Diabetes Mellitus/drug therapy/*metabolism/physiopathology, Disease Models, Fahmy Joseph N, Femoral Artery/metabolism/physiopathology, Free radical biology & medicine, Geldenhuys Werner J, HEK293 Cells, Humans, Inbred C57BL, Lipid Peroxidation, Male, Mice, NEOMED College of Medicine, Patch-Clamp Techniques, Post-Translational, Sinharoy Pritam, Thodeti Charles K, TRPV Cation Channels/genetics/*metabolism, Vasodilation/drug effects
A bouquet for a broken heart: can flowers repair a damaged heart?
Tags: 2015, angiogenesis, Animals, Circulation research, Coronary Vessels, Coronary Vessels/*physiopathology, Department of Integrative Medical Sciences, Editorials, endocardium, Endocardium/*physiopathology, endothelial cells, Endothelium, myocardial infarction, Myocardial Infarction/*physiopathology, NEOMED College of Medicine, Thodeti Charles K, Vascular/*physiopathology
A brief etymology of the collateral circulation.
Tags: *Cardiology, *Collateral Circulation/physiology, *Terminology as Topic, 2014, Arteriosclerosis, thrombosis, and vascular biology, Blood Vessels/embryology/growth & development, Chilian William M, Collateral Circulation, Deindl Elisabeth, Department of Integrative Medical Sciences, Faber James E, Humans, myocardial ischemia, NEOMED College of Medicine, Neovascularization, peripheral arterial disease, Physiologic/physiology, Simons Michael, stroke, van Royen Niels
A metabolic stress-inducible miR-34a-HNF4alpha pathway regulates lipid and lipoprotein metabolism.
Tags: 2015, Animals, Apolipoproteins E/genetics, Atherosclerosis/genetics/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus, Experimental/genetics/metabolism, Hep G2 Cells, Hepatocyte Nuclear Factor 4/*genetics/metabolism, Humans, Knockout, LDL/genetics, Li Yuanyuan, Lipid Metabolism/*genetics, Lipoproteins/metabolism, Liver/metabolism, Mice, MicroRNAs/*genetics/metabolism, Middle Aged, Nature communications, NEOMED College of Medicine, Non-alcoholic Fatty Liver Disease/*genetics/metabolism, Physiological/*genetics, Receptors, Stress, Triglycerides/*metabolism, Xu Jiesi, Xu Yang, Yin Liya, Zalzala Munaf, Zhang Yanqiao
A noninflammatory interleukin-1beta fragment stimulates fetal lung fluid absorption in guinea pigs.
Tags: 2007, Absorption, Adrenergic, Adrenocorticotropic Hormone/blood, Animals, Beard LaMonta L, beta/analysis, Body Fluids/drug effects/metabolism, Department of Integrative Medical Sciences, Epithelial Sodium Channels/genetics, Female, Fetus/drug effects, Folkesson Hans G, Guinea Pigs, Hydrocortisone/biosynthesis, Interleukin-1beta/*pharmacology, Li Tianbo, Lung/*drug effects/metabolism, Messenger/analysis, NEOMED College of Medicine, Oxytocin/pharmacology, Peptide Fragments/*pharmacology, Pregnancy, Receptors, RNA, The Journal of pharmacology and experimental therapeutics, Varadarajulu Shilpa, Yun June
A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.
Tags: 2010, Calcitriol/*metabolism, Calcitriol/pharmacology, Cell Membrane/drug effects/metabolism, Cell Nucleus/drug effects/metabolism, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/antagonists & inhibitors/genetics, Department of Integrative Medical Sciences, Ellis Ewa, Enzyme Activation/drug effects, Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors, Genetic/genetics, Han Shuxin, Hep G2 Cells, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/*drug effects/enzymology/*metabolism, Humans, Intracellular Space/drug effects/metabolism, Li Tiangang, Ligands, Lithocholic Acid/*pharmacology, Mitogen-Activated Protein Kinase Kinases/metabolism, Molecular endocrinology (Baltimore, Md.), NEOMED College of Medicine, Phosphorylation/drug effects, Phosphotyrosine/metabolism, Promoter Regions, Protein Kinase Inhibitors/pharmacology, Protein Transport/drug effects, Proto-Oncogene Proteins c-raf/metabolism, Receptors, Retinoid X Receptor alpha/metabolism, Signal Transduction/*drug effects, src-Family Kinases/metabolism, Steroid Hydroxylases/genetics/metabolism, Strom Stephen, Vitamin D3 24-Hydroxylase
A Novel Exercise Testing Algorithm to Diagnose Mitochondrial Myopathy.
Tags: 2021, Bhatia Rajeev, Cardiopulmonary exercise testing, Cohen BH, Department of Integrative Medical Sciences, Department of Pediatrics, February 2021 List, journalArticle, McNinch N, Mitochondrial myopathy, Muscle & nerve, NEOMED College of Medicine, O2 /Work slope, O2), Oxygen uptake (V&c.dotab, Oxygen Uptake Efficiency Slope (OUES), V&c.dotab
A Novel Murine Model to Study Postnatal Coronary Collateral Growth by Lineage Tracing
Tags: 2019, Chilian William M, Circulation research, Department of Anatomy & Neurobiology, Department of Integrative Medical Sciences, Enrick Molly, Gadd James, Jamaiyar Anurag, Juguilon Cody, NEOMED College of Graduate Studies Student, NEOMED College of Medicine, NEOMED College of Medicine Postdoc, NEOMED Postdoc Publications, NEOMED Student Publications, Richardson Devan, Wang Tao, Yin Liya
A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome.
Tags: 2017, Calcium/calmodulin-dependent protein kinase kinase-1, Cardiac disease, Cardiac regeneration, Department of Integrative Medical Sciences, Dong Feng, Duan Zhong-Hui, Kiedrowski Matthew, Mayorga Maritza E, Mesenchymal stem cells, NEOMED College of Medicine, Patnaik Shyam, Penn Marc S, Secretome, Stem cells translational medicine
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.
Tags: 2007, Bile Acids and Salts/metabolism, Carcinoma, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology, Gastroenterology, Genetic/drug effects/*physiology, Hepatocellular/*metabolism/pathology, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/drug effects/*metabolism/pathology, Humans, Hydroxamic Acids/pharmacology, Li Tiangang, Liver Neoplasms/*metabolism/pathology, Messenger/metabolism, NEOMED College of Medicine, RNA, Signal Transduction/physiology, Smad3 Protein/metabolism, Transcription, Transforming Growth Factor beta1/*metabolism, Tumor
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.
Tags: 2011, BILE acids, Busby Scott A, Department of Integrative Medical Sciences, Griffin Patrick R, Homeostasis, HYPOGLYCEMIC agents, Insulin Resistance, LABORATORY mice, LECITHIN, Lee Jae Man, Lee Yoon-Kwang, Mamrosh Jennifer L, Moore David D, Nature, NEOMED College of Medicine, Ortlund Eric A, Pathak Manish C, triglycerides
A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.
Tags: 2007, Allen Kristi L, Apoptosis Regulatory Proteins/metabolism, Apoptosis/*drug effects, Awad Keytam S, bcl-2-Associated X Protein/metabolism, Caspase 3/metabolism, Caspase 9/metabolism, Cultured/drug effects, DeLucia Angelo L, Department of Integrative Medical Sciences, Enzyme Activation/drug effects, Female, Genetic, Humans, Luciferases, Lynch William P, Masoprocol/*analogs & derivatives/therapeutic use, Molecular carcinogenesis, NEOMED College of Medicine, Oncogene Proteins, Plants/chemistry, Proto-Oncogene Proteins/metabolism, Repressor Proteins/*metabolism, Transcription, Tschantz Deidra R, Tumor Cells, Tumor Suppressor Protein p53/genetics/*metabolism, Uterine Cervical Neoplasms/*drug therapy/metabolism/pathology, Viral/*metabolism
A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.
Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques
A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes.
Tags: 2010, 3' Untranslated Regions/genetics, Base Sequence, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Department of Integrative Medical Sciences, Enzymologic/drug effects/*genetics, Fibroblast Growth Factors/pharmacology, Gene Expression Regulation, Genetic/drug effects/genetics, Hep G2 Cells, Hepatocytes/drug effects/enzymology/*metabolism, Humans, Isoxazoles/pharmacology, Journal of lipid research, Li Tiangang, MicroRNAs/*genetics/*metabolism, NEOMED College of Medicine, Oligonucleotide Array Sequence Analysis, Owsley Erika, Post-Transcriptional/drug effects/genetics, RNA Processing, Song Kwang-Hoon, Transcription
A TRP to cardiac fibroblast differentiation.
Tags: *Calcium Signaling, *Cell Differentiation, *Cell Transdifferentiation, *Mechanotransduction, *Wound Healing, 2013, Animals, Atrial Fibrillation/*metabolism, cardiac fibroblast, Cellular, Channels (Austin, Tex.), Department of Integrative Medical Sciences, differentiation, ECM stiffness, Female, Fibroblasts/*metabolism/*physiology, Humans, integrin, Male, mechanical signaling, Meszaros J Gary, myofibroblast, Myofibroblasts/*cytology/*metabolism, NEOMED College of Medicine, Paruchuri Sailaja, Rho/ROCK, Thodeti Charles K, TRPC Cation Channels/*metabolism, TRPM Cation Channels/*metabolism, TRPV Cation Channels/*metabolism, TRPV4
Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction.
Tags: 2012, Adapala Ravi K, Animal, Animals, Apoptosis/physiology, Bonaldo Paolo, Cardiac/pathology/physiology, Chilian William M, Circulation research, Collagen Type VI/*genetics/*metabolism, Department of Integrative Medical Sciences, Disease Models, Echocardiography, Extracellular Matrix/metabolism/pathology, Fibrosis/genetics/pathology/physiopathology, Hodnichak Cheryl, Knockout, Luther Daniel J, Male, Meszaros J Gary, Mice, Myocardial Infarction/diagnostic imaging/*genetics/*physiopathology, Myocytes, NEOMED College of Medicine, Shamhart Patricia E, Thodeti Charles K, Ventricular Remodeling/*physiology, Weihrauch Dorothee
Abstract 17248: The role of microRNA-21 in regulating the coronary microcirculation in diabetes
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.
Tags: 2016, Adapala R K, Animals, Calcium Signaling/genetics, Cappelli H C, Carcinoma, Cell Line, Cell Proliferation/drug effects, Chilian W M, Cisplatin/administration & dosage, Department of Integrative Medical Sciences, Dudley A C, Endothelium, Gene Expression Regulation, Ghosh K, Humans, Ingber D E, Keshamouni V, Klagsbrun M, Leucine/administration & dosage/analogs & derivatives, Lewis Lung/drug therapy/*genetics/pathology, Meszaros J G, Mice, NEOMED College of Medicine, Neoplastic/drug effects, Neovascularization, Oncogene, Paruchuri S, Pathologic/drug therapy/*genetics/pathology, Sulfonamides/administration & dosage, Thodeti C K, Thoppil R J, TRPV Cation Channels/agonists/biosynthesis/*genetics, Tumor, Vascular Endothelial Growth Factor A/genetics, Vascular/drug effects/*pathology
Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits.
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Acute alcohol intoxication impairs SHH-GLI1 signaling and activation of primitive hematopoietic precursor cells in the early stage of host response to bacteremia.
Tags: 2020, Alcohol, alcoholism, Alcoholism, Clinical and Experimental Research, August 2020 List, bacteremia, Clinical and Experimental Research, Department of Integrative Medical Sciences, hematopoietic stem cells, host response, journalArticle, NEOMED College of Medicine, Shi X, Simms KJ, sonic hedgehog, Zhang P
Acute alcohol intoxication impairs sonic hedgehog-GLI1 signaling and activation of primitive hematopoietic precursor cells in the early stage of host response to bacteremia.
Tags: 2020, Alcohol, alcoholism, Alcoholism, Clinical and Experimental Research, bacteremia, Clinical and Experimental Research, Department of Integrative Medical Sciences, hematopoietic stem cells, host response, journalArticle, NEOMED College of Medicine, September 2020 List, Shi X, Simms KJ, sonic hedgehog, Zhang P
Administration of a synthetic antiprotease reduces smoke-induced lung injury.
Tags: *Lung Injury, 1990, alpha-Macroglobulins/physiology, Animals, Department of Integrative Medical Sciences, Endopeptidases/physiology, Female, Flynn J T, Gabexate, Guanidines/*pharmacology, Herndon D N, Journal of applied physiology (Bethesda, Md. : 1985), Kimura R, NEOMED College of Medicine, Neutrophils/physiology, Niehaus G D, Pulmonary Edema/etiology/prevention & control, Pulmonary Gas Exchange/drug effects, Serine Proteinase Inhibitors/*pharmacology, Sheep, Smoke Inhalation Injury/*drug therapy/etiology/physiopathology, Traber D L, Traber L D
Aflatoxin B1 metabolism by 3-methylcholanthrene-induced hamster hepatic cytochrome P-450s.
Tags: 1990, Aflatoxin B1, Aflatoxins/immunology/*metabolism, Animals, Antibodies/immunology, Chiang J Y, Cricetinae, Cytochrome P-450 Enzyme System/biosynthesis/isolation & purification/*metabolism, Department of Integrative Medical Sciences, Enzyme Induction/drug effects, Enzymologic, Gene Expression Regulation, Inbred Strains, Journal of biochemical toxicology, Lai T S, Liver/drug effects/*enzymology, Liver/enzymology, Mesocricetus, Methylcholanthrene/*pharmacology, Microsomes, Mutagenicity Tests, NEOMED College of Medicine, Rats, Salmonella typhimurium/enzymology/genetics, Subcellular Fractions/drug effects/enzymology
Alcohol abuse and disorder of granulopoiesis.
Tags: *Stem cells, 2019, Alcohol abuse, bacterial infection, Bao Jianxin, bone marrow, cell signaling, DeLucia Angelo L, Department of Integrative Medical Sciences, Granulopoiesis, Immune defense, Leukopenia, NEOMED College of Medicine, Pharmacology & therapeutics, progenitor cells, Shi Xin, the granulopoietic response, Zhang Ping
ALCOHOL INHIBITS UPREGULATION OF GBP7 EXPRESSION BY HEMATOPOIETIC STEM/PROGENITOR CELLS DURING THE GRANULOPOIETIC RESPONSE TO SEPTIC INFECTION
Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis.
Tags: *Aldehyde Reductase/genetics/metabolism, 2011, Adenoviridae, Animal, Animals, Blood Glucose/*metabolism, Chiang John Y L, Cholesterol/analysis, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus/genetics/*metabolism/physiopathology, Disease Models, Fatty Liver/genetics/*metabolism/physiopathology, Ge Xuemei, Gene Expression, Genetic Vectors, Gluconeogenesis/genetics, Homeostasis, Humans, Journal of lipid research, Li Tiangang, Liver/*metabolism/physiopathology, Ma Huiyan, Malondialdehyde/blood, Mice, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, Transfection, Transgenic, Triglycerides/analysis, Yin Liya, Zhang Yanqiao
Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction.
Tags: *Cardiovascular regeneration, *Ischemic heart diseases, *Micro-bundle scaffold, *Myocardial infarction, *Neovascularization, *Stem cells, *Tissue Scaffolds, *Vascular progenitor cells, 2017, Animal, Animals, Basic research in cardiology, Cell Differentiation, Cell Proliferation, Cell Survival, Cells, Chilian William M, Coculture Techniques, Cultured, Cumpston Devan, Department of Integrative Medical Sciences, Disease Models, Dong Feng, Endothelial Progenitor Cells/metabolism/*transplantation, Enrick Molly, Fibroblast Growth Factor 2/metabolism, Hakobyan Tatev, Jamaiyar Anurag, Janota Danielle, Kolz Christopher L, Lactic Acid/*chemistry, Muscle, Myocardial Infarction/metabolism/pathology/physiopathology/*surgery, Myocardium/metabolism/*pathology, Myocytes, NEOMED College of Medicine, Newby Bi-Min Zhang, Ohanyan Vahagn, Paracrine Communication, Phenotype, Physiologic, Polyglycolic Acid/*chemistry, Polylactic Acid-Polyglycolic Acid Copolymer, Rats, Signal Transduction, Smooth, Smooth Muscle/metabolism/*transplantation, Song Hokyung, Sprague-Dawley, Stevanov Kelly, Time Factors, Tissue Engineering/*methods, Vascular Endothelial Growth Factor A/metabolism, Vascular/metabolism/*transplantation, Ventricular Remodeling, Wan Weiguo, Yin Liya
All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.
Tags: 2014, Animals, Axe David, Basic Helix-Loop-Helix Transcription Factors/genetics, Blood Glucose/analysis, Chiang John Y L, Cook Aaron, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Fatty Liver/*drug therapy/metabolism, Gene Expression Regulation, Genetic, Hardwick James P, Hepatology (Baltimore, Md.), Inbred C57BL, Kim Chun-Ki, Kim Seong-Chul, Lee Mikang, Lee Yoon-Kwang, Li Tiangang, Lipid Metabolism, Liver/metabolism, Male, Mice, Moore David D, NEOMED College of Medicine, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease, PPAR gamma/*genetics, Receptors, Repressor Proteins/genetics, Retinoic Acid Receptor alpha, Retinoic Acid/physiology, Smallwood Nicole, Transcription, Tretinoin/pharmacology/*therapeutic use
Alzheimers disease-related pathology and impaired cognitive function associate with reduced O-GLCNAC transferase in aged metabolic syndrome KKAY(+/-) mice
AMP-activated kinase "Keaps" ischemia/reperfusion-induced necroptosis under control.
Tags: *AMP-Activated Protein Kinases, *AMPK, *Apoptosis, *Ischemia/reperfusion, *Myocardium, *Necroptosis, *Necrosis, 2018, Apoptosis, Department of Integrative Medical Sciences, Humans, International journal of cardiology, Kanugula Anantha K, Myocardial Reperfusion Injury, Myocardium, NEOMED College of Medicine, Thodeti Charles K
Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts.
Tags: 2008, Acetophenones/pharmacology, Angiotensin II/*physiology, Animals, Benzopyrans/pharmacology, Calcium/*metabolism, Cell Proliferation, Cells, Cultured, Department of Integrative Medical Sciences, Enzyme Activation, ErbB Receptors/metabolism, Fibroblasts/*metabolism, Hypertension (Dallas, Tex. : 1979), Male, Meszaros J Gary, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Myocardium/*cytology/metabolism, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Phorbol Esters/pharmacology, Phosphorylation, Protein Kinase C-delta/genetics/*metabolism, Rats, Shamhart Patricia E, Signal Transduction/physiology, Sprague-Dawley
Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro.
Tags: *Comovirus, 2016, Aorta/*metabolism, Atherosclerosis/*drug therapy/therapy, Azo Compounds/chemistry, Cell Proliferation, Cells, Chlorides/*chemistry, Chromium Compounds/*chemistry, Cultured, Cytokines/metabolism, Czech Tori, Department of Integrative Medical Sciences, Drug Delivery Systems, Electron, Fluorescence, Ganguly Rituparna, Glucose/chemistry, Humans, Hyperglycemia/*metabolism, Lipids/chemistry, Microscopy, Myer Ashley B, Myocytes, Nanoparticles/chemistry, Nanoscale, NEOMED College of Medicine, NF-kappa B/metabolism, Proliferating Cell Nuclear Antigen/chemistry, Raman Priya, Sahu Soumyadip, Smooth Muscle/*metabolism, Spectrophotometry, Steinmetz Nicole F, Transforming Growth Factor beta/metabolism, Transmission, Ultraviolet, Wen Amy M
Astrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression
Tags: 2019, Astrocytes, Cardona Sandra M, Das Alvin S, Department of Integrative Medical Sciences, Dunphy Jaclyn M, Frontiers in neuroscience, glia, Journal Article, Lynch Connor R, Lynch William P, NEOMED College of Medicine, neural progenitor cells, Neural stem cells, neurotropism, November 2019 Update, retrovirus, spongiform neurodegeneration, virus suppression
Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling.
Tags: 2017, Adenosine Triphosphate – Metabolism, Adenosine Triphosphate/*metabolism, Ammi Azzdine Y, Animal Studies, Animals, Belcik J Todd, Chilian William M, Chon Chae Ryung, Circulation, contrast echocardiography, Davidson Brian P, Department of Integrative Medical Sciences, Equipment and Supplies, Field Joshua, Harmann Leanne, Hemodynamics, Humans, Inbred C57BL, Liang Sherry, Linden Joel, Lindner Jonathan R, Male, Mice, Microbubbles, Microcirculation, Muscle, NEOMED College of Medicine, Neurotransmitter Agents – Metabolism, Perfusion, Purinergic Agents/*metabolism, Qi Yue, Signal Transduction, Skeletal – Blood Supply, Skeletal/*blood supply, Ultrasonography – Methods, Ultrasonography/*methods, Wu Melinda D, Xie Aris, Yadava Mrinal
Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).
Tags: *Gene Expression Regulation, 1998, Animals, Bile Acids and Salts/genetics, Binding Sites/genetics, Biochemical and biophysical research communications, Carcinoma, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Complementary/analysis, Cultured, Department of Integrative Medical Sciences, DNA, DNA-Binding Proteins/metabolism/*physiology, Electrophoresis, Enzyme Activation/genetics, Foti D, Genetic, Hepatocellular, Humans, Kruppel-Like Transcription Factors, Liver/enzymology, NEOMED College of Medicine, Podophyllin/analogs & derivatives/metabolism, Podophyllotoxin/analogs & derivatives, Polyacrylamide Gel, Promoter Regions, Protein Binding/genetics, Rats, Stroup D, Transcription Factors/metabolism/*physiology, Tumor Cells
BCNU-induced gR2 defect mediates S-glutathionylation of Complex I and respiratory uncoupling in myocardium.
Tags: 2014, Alkylating/*adverse effects/pharmacology, Animals, Antineoplastic Agents, Biochemical pharmacology, Cardiotoxins/adverse effects/pharmacology, Carmustine/*adverse effects/pharmacology, Cattle, Cell Line, Chen Chwen-Lih, Chen Yeong-Renn, Complex I, Department of Integrative Medical Sciences, Electron Transport Complex I/chemistry/*metabolism, Fatty Acids, Glutathione reductase, Glutathione Reductase/*antagonists & inhibitors/metabolism, Glutathione/*metabolism, Guarini Giacinta, Heart Ventricles/drug effects/metabolism/physiopathology, Heart/*drug effects/metabolism, Ion Channels/metabolism, Kang Patrick T, Left/*chemically induced/metabolism/physiopathology, Male, Mice, Mitochondria, Mitochondrial Proteins/metabolism, NEOMED College of Medicine, Nonesterified/metabolism, Oxidative Stress, Oxidative Stress/drug effects, Post-Translational/drug effects, Protein Processing, Rats, Ren Pei, S-Glutathionylation, Sprague-Dawley, Superoxide Dismutase/genetics/metabolism, Systolic dysfunction, Transgenic, Uncoupling Protein 3, Ventricular Dysfunction
Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure.
Tags: 2009, Adrenergic, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/*metabolism, Body Fluids/*metabolism, Department of Integrative Medical Sciences, Epithelial Cells/drug effects/metabolism/pathology, Folkesson Hans G, Gene Expression Regulation/drug effects, Heart Failure/blood/diagnostic imaging/*metabolism/*pathology, Hormones/blood, Horne Walter I, Hyperplasia, Ion Channels/genetics/metabolism, Koshy Shyny, Li Tianbo, Luther Daniel J, Male, Maron Michael B, Messenger/genetics/metabolism, Meszaros J Gary, Myocardial Infarction/blood/diagnostic imaging/pathology, NEOMED College of Medicine, Ohanyan Vahagn, Pilati Charles F, Pulmonary Alveoli/drug effects/*pathology, Rats, Receptors, RNA, Sprague-Dawley, Terbutaline/pharmacology, Ultrasonography, Walro Jon M