Browse Items · NEOMED Bibliography Database

Promoting bone health in children and adolescents following solid organ transplantation.

Solid organ transplantation in children and adolescents provides many benefits through improving critical organ function, including better growth, development, cardiovascular status, and quality of life. Unfortunately, bone status may be adversely…

Improving pediatric readiness in general emergency departments: A prospective interventional study.

OBJECTIVE: To describe the impact of a national interventional collaborative on pediatric readiness within General Emergency Departments. STUDY DESIGN: A prospective, multicenter, interventional study measured pediatric readiness in general…

Mitochondrial diseases in North America: An analysis of the NAMDC Registry.

Objective: To describe clinical, biochemical, and genetic features of participants with mitochondrial diseases (MtDs) enrolled in the North American Mitochondrial Disease Consortium (NAMDC) Registry. Methods: This cross-sectional, multicenter,…

Tags: 2020, Akron Children's Hospital, Barca Emanuele, Bedoyan Jirair K, Buchsbaum Richard, Camp Kathryn, Cohen Bruce H, Cooley Victoria, criteria, DeBrosse Susanne D, Department of Integrative Medical Sciences, Department of Pediatrics, DiMauro Salvatore, DNA, Emmanuele Valentina, Engelstad Kristin, Enns Gregory M, Falk Marni J, Ganesh Jaya, Gavrilova Ralitza H, Goldstein Amy C, Grier Johnston, Gropman Andrea, Haas Richard, Hirano Michio, Journal Article, journalArticle, June 2020 Update I, Karaa Amel, Kriger Joshua, Krotoski Danuta, Larson Austin, Long Yuelin, melas, merrf, natural-history, NEOMED College of Medicine, Neurology. Genetics, nuclear, Parikh Sumit, Prevalence, Rosales Xiomara Q, Saneto Russell P, Scaglia Fernando, Schoenaker Robert, Stacpoole Peter W, Tarnopolsky Mark, Thompson John L P, Van Hove Johan L K, Vladutiu Georgirene D, Zolkipli-Cunningham Zarazuela

Utility of specific amino acid ratios in screening for pyruvate dehydrogenase complex deficiencies and other mitochondrial disorders associated with congenital lactic acidosis and newborn screening prospects.

Pyruvate dehydrogenase complex deficiencies (PDCDs) and other mitochondrial disorders (MtDs) can (a) result in congenital lactic acidosis with elevations of blood alanine (Ala) and proline (Pro), (b) lead to decreased ATP production, and (c) …

Exercise-Induced Dyspnea in Children and Adolescents: Differential Diagnosis

Exercise-induced dyspnea in children and adolescents can occur for many reasons. Although asthma is the common cause, failure to prevent exercise-induced asthma by pretreatment with a bronchodilator, such as albuterol, indicates that other etiologies…

Tags: 2019, Abu-Hasan M, adults, asthma, Bhatia R, Department of Pediatrics, hyperventilation, induced bronchoconstriction, June 2019 Update, NEOMED College of Medicine, Pediatric Annals, Pediatrics, vocal-cord dysfunction, Weinberger M

A Novel Exercise Testing Algorithm to Diagnose Mitochondrial Myopathy.

INTRODUCTION: Oxygen uptake efficiency slope (OUES) is a non-invasive cardiopulmonary exercise testing (CPET) measurement based on oxygen uptake (V&c.dotab;O(2) ) and minute ventilation (V&c.dotab;(E) ) and is a marker of the efficiency of oxygen…

Tags: 2021, Bhatia Rajeev, Cardiopulmonary exercise testing, Cohen BH, Department of Integrative Medical Sciences, Department of Pediatrics, February 2021 List, journalArticle, McNinch N, Mitochondrial myopathy, Muscle & nerve, NEOMED College of Medicine, O2 /Work slope, O2), Oxygen uptake (V&c.dotab, Oxygen Uptake Efficiency Slope (OUES), V&c.dotab

Epidemiology of vestibular schwannoma in the United States, 2004-2016.

BACKGROUND: Vestibular schwannomas (VS) are nonmalignant tumors of the eighth cranial nerve and are the most common nonmalignant nerve sheath tumor. This study provides the most comprehensive and current analysis of VS epidemiology in the United…

Ethyl vinyl chloride vapocoolant spray fails to decrease pain associated with intravenous cannulation in children.

The purpose of the study was to determine the effect of ethyl vinyl chloride vapocoolant spray on pain reported by children undergoing intravenous cannulation. A randomized, double-blinded, placebo-controlled trial was conducted on eligible children…

A thyroglossal duct cyst causing apnea and cyanosis in a neonate.

This is a case of a 3-week-old male who presented to the emergency department with intermittent apnea and cyanosis. While in the emergency department, he had respiratory compromise with stress and required intubation. Further evaluation confirmed the…

Tags: 2005, Airway Obstruction/etiology/therapy, Akron Children's Hospital, Apnea/*etiology/therapy, Christopher Norman C, Cyanosis/*etiology/therapy, Department of Emergency Medicine, Department of Pediatrics, Diaz Maria Carmen G, Humans, Infant, Intratracheal, Intubation, Male, NEOMED College of Medicine, Newborn, Pediatric emergency care, Stormorken Anne, Thyroglossal Cyst/*complications/*congenital

Effect of a standardized pharyngitis treatment protocol on use of antibiotics in a pediatric emergency department.

BACKGROUND: Pharyngitis is a common complaint in pediatric patients. If clinical parameters are used alone, bacterial pathogens will be wrongly implicated in many cases. A nonstandardized approach to the treatment of children with pharyngitis in an…

Providers' Ability to Identify Sentinel Injuries Concerning for Physical Abuse in Infants.

Tags: 2021, Bressler CJ, Department of Pediatrics, Eismann EA, Izsak E, journalArticle, Kim GJ, Makoroff K, May 2021 List, McPherson P, NEOMED College of Medicine, Pediatric emergency care, Shapiro RA, Spencer SP, Thackeray J, Vavul-Roediger L

Acute kidney injury associated with urinary stone disease in children and young adults presenting to a pediatric emergency department.

Background: Acute kidney injury (AKI) due to urinary stone disease (USD) is rare in adults; AKI rates in children with USD may be higher, and emerging data links stones to chronic kidney disease (CKD) development in adults. Methods: This study is a …

Prioritization of Pediatric Palliative Care Field-Advancement Activities in the United States: Results of a National Survey.

BACKGROUND: The field of pediatric palliative care (PPC) continues to encounter challenges and opportunities to improving access to high-quality PPC services. In early 2019, a workshop identified eleven potential "next step" actions, and …

Chemotherapy Strategies for Young Children Newly-Diagnosed with Medulloblastoma up to the Era of Molecular Profiling - A Comparative Outcomes Analysis

Using and interpreting electrodiagnostic tests.

Electrodiagnostic testing, consisting of nerve conduction studies and needle electrode examination, serves as an extension of a neurologic examination for evaluating a variety of focal and generalized neuromuscular conditions. By providing …

Tags: 2020, Akron Children's Hospital, Cleveland Clinic journal of medicine, Department of Pediatrics, Ginsberg MR, journalArticle, Levin K, Morren JA, NEOMED College of Medicine, October 2020 List

End of Life Outside of "Business Hours": A Retrospective Review Evaluating Time of Death and Provider Time at End of Life.

Introduction: Pediatric palliative care (PPC) benefits patients and families, while potentially creating emotional and resource-management burdens for providers. This study's purpose was to characterize the occurrence of deaths attended by PPC …

Tags: 2021, advance practice nurse, Brown M, compassion fatigue, Department of Family & Community Medicine, Department of Pediatrics, Friebert S, Grossoehme DH, Hardy-Gomez M, Journal of palliative medicine, journalArticle, July 2021 List, NEOMED College of Medicine, of-life, Palliative Care, Pediatric, pediatric palliative care, physician, Strasshofer D

Predictors of technology success in patients with cystic fibrosis-related diabetes

Tags: 2020, Department of Pediatrics, Jain A, journalArticle, Kaminski B, Kutney KA, October 2020 List, Pediatric Pulmonology

What Is That? Innumerable Mysterious Densities Identified on Abdominal Imaging.

Radiopaque densities can be observed on imaging after the ingestion of either foreign bodies or some medications. Our case report discusses an 11-year-old boy with autism spectrum disorder and attention deficient disorder who presented to the…

Tags: 2020, Akron Children's Hospital, Blackford Martha G, Department of Pediatrics, Kaiser Nicole, NEOMED College of Medicine, Pediatric emergency care

Adolescents with urinary stones have elevated urine levels of inflammatory mediators

Urinary stones are increasing in children, primarily during adolescence. Although urinary stones are often viewed in the context of intermittent stone events, increasing evidence indicates that stones are a metabolic process associated with chronic…

Tags: 2019, Biomarker, Cytokine, Department of Pediatrics, Innate immunity, Interleukin, June 2019 Update, Ketz John, Kusumi Kirsten, NEOMED College of Medicine, Safadi Fayez, Saxena Vijay, Schwaderer Andrew, Spencer John David, urolithiasis

Bone mineral density in adolescent urinary stone formers: is sex important?

Urinary stone disease (USD) is affecting a greater number of children and low bone mineral density (BMD) and increased skeletal fractures have been demonstrated in stone patients; however, the mechanism(s) driving bone disease remain unclear. This…

Acute Tramadol Ingestion With Transient Acute Kidney Injury in an Adolescent Female.

Renal toxicity has been described with tramadol overdoses; however, it is typically associated with rhabdomyolysis, multiorgan failure and/or mortality. Our patient was a 16-year-old female who was evaluated following an intentional tramadol…

The efficacy of early propranolol administration at reducing PTSD symptoms in pediatric injury patients: A pilot study.

Initial research supports the use of propranolol to prevent posttraumatic stress disorder (PTSD); research has not examined pharmacological prevention for children. Twenty-nine injury patients (ages 10–18 years old) at risk for PTSD were randomized…

Emergency medical service and in-hospital vital signs as predictors of subsequent PTSD symptom severity in pediatric injury patients.

Background: The present study investigated the extent to which heart rate (HR) levels soon after a traumatic event predicted posttraumatic stress disorder (PTSD) symptom severity assessed 6 weeks and 6 months later in child trauma victims. Methods:…

Tags: 2006, Akron Children's Hospital, CARDIOVASCULAR diseases, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, HEART beat, Journal of Child Psychology & Psychiatry, JUVENILE diseases, MEDICAL emergencies, NEOMED College of Medicine, Nugent Nicole R, PEDIATRIC trauma centers, POST-traumatic stress disorder

Initial physiological responses and perceived hyperarousal predict subsequent emotional numbing in pediatric injury patients.

The present study tested the hypothesis that acute posttraumatic hyperarousal would lead to the development of emotional numbing (EN) symptoms in a pediatric injury population. Eighty-two youths aged 8–18 years were recruited from the emergency…

Tags: 2006, Akron Children's Hospital, Avoidance (Psychology), CHILDREN'S accidents, CHILDREN'S injuries, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, DEPRESSION in children, EMOTIONS (Psychology), HEART beat, HOSPITAL emergency services, Journal of Traumatic Stress, NEOMED College of Medicine, Nugent Nicole R, POST-traumatic stress disorder, Urine

Parental Posttraumatic Stress Symptoms as a Moderator of Child's Acute Biological Response and Subsequent Posttraumatic Stress Symptoms in Pediatric Injury Patients.

Objective To examine how parental responses following pediatric injury may influence their child's posttraumatic stress symptoms (PTSS). Methods Heart rate (HR) from 82 pediatric injury patients was measured during emergency medical services (EMSs)…

Tags: 2007, Akron Children's Hospital, Children, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, Journal of Pediatric Psychology, NEOMED College of Medicine, NEUROSES, Nugent Nicole R, Ostrowski Sarah, Parents, POST-traumatic stress disorder, STRESS (Psychology)

The influence of family environment on dissociation in pediatric injury patients.

Tags: 2011, Accidents – Adverse Effects, Adolescence, Akron Children's Hospital, Analysis of Covariance, Bivariate Statistics, Checklists, Chi Square Test, Child, Child Development, Christopher Norman C, Clinical Child Psychology & Psychiatry, Confidence Intervals, Correlational Studies, Data Analysis Software, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, Descriptive Research, Descriptive Statistics, Dissociative Disorders – Risk Factors, Family, Family Coping, Family Relations, Female, Funding Source, Human, Income, Interview Guides, Male, NEOMED College of Medicine, Nugent Nicole R, Ohio, Parametric Statistics, Parenting Education, Patient-Family Relations, Pearson's Correlation Coefficient, Pretest-Posttest Design, Prospective Studies, Questionnaires, Retrospective Design, Scales, Self Report, Semi-Structured Interview, Severity of Illness Indices, Sledjeski Eve M, Social Environment, Socioeconomic Factors, Wounds and Injuries – Complications

Brief Report: The Impact of Maternal Posttraumatic Stress Disorder Symptoms and Child Gender on Risk for Persistent Posttraumatic Stress Disorder Symptoms in Child Trauma Victims.

Objective To longitudinally examine the impact of maternal posttraumatic stress disorder symptoms (PTSS) on child adjustment following a child's traumatic injury, focusing on child gender differences. Methods Forty-one child traumatic injury victims…

Tags: 2007, Akron Children's Hospital, Children, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, Journal of Pediatric Psychology, NEOMED College of Medicine, NEUROSES, Ostrowski Sarah A, POST-traumatic stress disorder, STRESS (Psychology), TRAUMATIC neuroses

Acute child and mother psychophysiological responses and subsequent PTSD symptoms following a child's traumatic event.

This study examined the relationship between acute cortisol responses to trauma and subsequent PTSD symptoms (PTSS) in children and their biological mothers. Urinary cortisol levels were assessed in 54 children aged 8–18 upon admission to a level-1…

Tags: 2007, Akron Children's Hospital, Children, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, Hydrocortisone, Journal of Traumatic Stress, MENTAL depression, Mothers, NEOMED College of Medicine, Ostrowski Sarah A, POST-traumatic stress disorder, Research, STATISTICAL sampling, Trauma Centers, Urine, van Dulmen Manfred HM

The Impact of Caregiver Distress on the Longitudinal Development of Child Acute Post-traumatic Stress Disorder Symptoms in Pediatric Injury Victims.

Objective The present study prospectively examined the development of child PTSD symptoms (PTSS) and the impact of caregiver PTSS on child PTSS following injury. Methods One hundred and eighteen ED patients and their caregivers were interviewed…

Tags: 2011, Akron Children's Hospital, Analysis of Variance, CHILD health services, CHILDREN'S injuries, Christopher Norman C, Ciesla Jeffrey A, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, Irish Leah, Journal of Pediatric Psychology, Lee Timothy J, NEOMED College of Medicine, Ostrowski Sarah A, POST-traumatic stress disorder in children, Psychology, STRUCTURAL equation modeling, VARIATION in child development

Diagnosis of 'possible' mitochondrial disease: an existential crisis.

Primary genetic mitochondrial diseases are often difficult to diagnose, and the term 'possible' mitochondrial disease is used frequently by clinicians when such a diagnosis is suspected. There are now many known phenocopies of mitochondrial disease.…

Diagnosis of 'possible' mitochondrial disease: an existential crisis.

Primary genetic mitochondrial diseases are often difficult to diagnose, and the term 'possible' mitochondrial disease is used frequently by clinicians when such a diagnosis is suspected. There are now many known phenocopies of mitochondrial disease.…

Epidemiology of brainstem high-grade gliomas in children and adolescents in the united states, 2000-2017.

BACKGROUND: Limited population-based data exists for the brainstem gliomas for children ages ≤19 years, which includes high-grade aggressively-growing tumors such as diffuse intrinsic pontine glioma (DIPG). We examined the overall incidence and …

Pediatric Urolithiasis: Clinical Predictors in the Emergency Department.

OBJECTIVE: The objective of this study was to identify factors that predict the presence of urolithiasis detected with unenhanced computed tomography (UCT) in children. METHODS: A retrospective study of all subjects \textless21 years of age who…

Tags: 2009, Akron Children's Hospital, BLADDER stones, CHILDREN'S hospitals, Christopher Norman C, Department of Emergency Medicine, Department of Pediatrics, DISEASE risk factors, HEMATURIA in children, LOGISTIC regression analysis, McMahon Daniel R, NEOMED College of Medicine, PEDIATRIC diagnosis, Pediatrics, Persaud Andre C, Stevenson Michelle D, Tomography, Urinalysis, URINARY calculi – Diagnosis

The educational experience of pediatric emergency medicine fellows in the use and application of procedural sedation/analgesia.

OBJECTIVES: The purpose of this study is to describe the clinical and educational experience provided to the pediatric emergency medicine (PEM) fellows in procedural sedation/analgesia during their course of training. METHODS: A nonanonymous survey…

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma.

The paternally imprinted neuronatin (NNAT) gene has been identified as a target of aberrant epigenetic silencing in diverse cancers, but no association with pediatric bone cancers has been reported to date. In screening childhood cancers, we…

Emergent high fatality lung disease in systemic juvenile arthritis

OBJECTIVE: To investigate the characteristics and risk factors of a novel parenchymal lung disease (LD), increasingly detected in systemic juvenile idiopathic arthritis (sJIA). METHODS: In a multicentre retrospective study, 61 cases were investigated…

Tags: 2019, Abulaban Khalid, adult onset still's disease, Akron Children's Hospital, Annals of the rheumatic diseases, Balise Raymond, Baszis Kevin, Behrens Edward M, Bejerano Gill, Birgmeier Johannes, Birmingham James, Bouzoubaa Layla, Canna Scott, Casey Alicia, Chen Guangbo, Childhood Arthritis and Rheumatology Research Alliance Registry Investigators, Cidon Michal, Cron Randy Q, Davis Mark M, De Aliva, De Benedetti Fabrizio, Department of Pediatrics, Desai Tushar, Deterding Robin, Deutsch Gail H, DMARDs (biologic), Ferguson Ian, Fishman Martha P, Goodman Steven I, Graham T Brent, Grom Alexei A, Guillerman R Paul, Haines Kathleen, Hazen Melissa, Henderson Lauren A, Ho Assunta, Ibarra Maria, Inflammation, Inman Christi J, Jagadeesh Karthik, Jerath Rita, Journal Article, juvenile idiopathic arthritis, Khatri Purvesh, Khawaja Khulood, Kingsbury Daniel J, Klein-Gitelman Marisa, Lai Khanh, Lapidus Sivia, Leung Ann N, Lin Clara, Lin Jenny, Liptzin Deborah R, Lu Ying, Mellins Elizabeth D, Milojevic Diana, Mombourquette Joy, NEOMED College of Medicine, November 2019 Update, Onel Karen, Ozen Seza, Perez Maria, Phillippi Kathryn, Prahalad Sampath, Radhakrishna Suhas, Reinhardt Adam, Riskalla Mona, Rosenwasser Natalie, Roth Johannes, Saper Vivian E, Schneider Rayfel, Schonenberg-Meinema Dieneke, Schulert Grant, Shenoi Susan, Smith Judith A, Sönmez Hafize Emine, Stoll Matthew L, Tian Lu, Towe Christopher, Treatment, Vargas Sara O, Vehe Richard K, Xu Jianpeng, Yang Jacqueline, Young Lisa R

"Living life as if i never had cancer": A study of the meaning of living well in adolescents and young adults who have experienced cancer

Background Cancer diagnoses pose challenges to adolescents' and young adults' (AYA) physical, mental, and emotional health, and developmental tasks. In order for AYAs, caregivers, clinicians, and other collaborators to optimize health outcomes…

Practical Challenges and Considerations for Early Introduction of Potential Food Allergens for Prevention of Food Allergy.

Recent randomized controlled trials aimed at the prevention of food allergy have led to sweeping changes in food allergy prevention guidelines. Emphasis is now on the introduction of potential food allergens, particularly peanut and egg, rather…

Tags: 2020, Complementary feeding, December 2020 List, Department of Pediatrics, Early introduction, Food allergy, Groetch M, guidelines, Infant nutrition, journalArticle, Mack DP, NEOMED College of Medicine, Prevention, Schroer B, The Journal Of Allergy And Clinical Immunology. In Practice, Venter C

Screening for adolescent depression in a pediatric emergency department.

OBJECTIVES: To describe the prevalence of depressive symptoms in adolescents presenting to the emergency department (ED) and to describe their demographics and outcomes compared with adolescents endorsing low levels of depressive symptoms. METHODS:…

Tags: *Adolescent Behavior, 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, Adolescent, Adult, Age Distribution, Akron Children's Hospital, Alexander Heather, Christopher Norman C, Comorbidity, Cross-Sectional Studies, Department of Emergency Medicine, Department of Pediatrics, Depression/classification/*diagnosis/*epidemiology, Emergency Service, Female, Fenn Robin L, Hospital/*statistics & numerical data, Hospitalization/statistics & numerical data, Humans, Logistic Models, Luxmore Brett, Male, Mass Screening/*instrumentation/*statistics & numerical data, NEOMED College of Medicine, Ohio/epidemiology, Patient Participation/statistics & numerical data, Pediatrics/*statistics & numerical data, Prevalence, Psychiatric Status Rating Scales, Scott Emily Gale, Transportation of Patients/statistics & numerical data, Wounds and Injuries/epidemiology

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