Browse Items (332 total)
- Tags: Department of Pharmaceutical Sciences
The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6.
Tags: *gp91(phox), *Microglia, *MPTP, *Na(v)1.6, *Neuroinflammation, *Parkinson's disease, *TNF-alpha, *Voltage-gated sodium channels, *Zonisamide, 2018, Department of Pharmaceutical Sciences, Experimental neurology, Gearing Marla, Hossain Muhammad M, NEOMED College of Pharmacy, Reuhl Kenneth, Richardson Jason R, Weig Blair, Wu Long-Jun
A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis.
Tags: *Flux, *Glutathione, *Heavy water, *Mass spectrometer, *NAFLD, *NASH, *Oxidative Stress, *Western Diet, 2016, Animal, Animals, Antioxidants/metabolism, Department of Pharmaceutical Sciences, Diet, Disease Models, Free radical biology & medicine, Glutathione/blood/*metabolism, Humans, Kasumov Takhar, LDL/blood/*genetics/metabolism, Lee Kwangwon, Li Ling, Liver/*metabolism/pathology, Lopez Rocio, McCullough Arthur, Mice, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/blood/*genetics/pathology, Oxidative Stress/genetics, Previs Stephen F, Receptors, Western/adverse effects, Willard Belinda, Zhang Guo-Fang
Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.
Tags: *Ceruloplasmin, *Deamidation, *Heavy water metabolic labeling, *High resolution mass spectrometry, *Iron metabolism, *LC-MS/MS, *Non-enzymatic glycation, *Oxidative Stress, *Protein Processing, *Proteome dynamics, *Serotransferrin, *Type 2 diabetes mellitus, 2017, Adult, Amino Acid Sequence, Bena James, Case-Control Studies, Ceruloplasmin/genetics/*metabolism, Department of Pharmaceutical Sciences, Deuterium/metabolism, Diabetes Mellitus, Diabetic, Diet, Female, Free radical biology & medicine, Gene Expression Regulation, Glycated Hemoglobin A/genetics/metabolism, Glycosylation, Golizeh Makan, Humans, Ilchenko Serguei, Iron/*metabolism, Isotope Labeling, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Male, Middle Aged, NEOMED College of Pharmacy, Osme Abdullah, Oxidation-Reduction, Oxidative Stress, Post-Translational, Proteolysis, Sadygov Rovshan G, Transferrin/genetics/*metabolism, Type 2/diet therapy/genetics/*metabolism/pathology
Detection of single mRNAs in individual cells of the auditory system.
Tags: 2018, Bao Jianxin, Chen Yingying, Cochlea, Crish Samuel D, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Hearing research, Immunohistochemistry, Inner hair cell, Lei Debin, Nelson Charlie N, Nelson Jovitha, NEOMED College of Medicine, NEOMED College of Pharmacy, Outer hair cell, Salehi Pezhman, Single-molecule fluorescence in situ hybridization, Spiral ganglion neuron, Zuo Hongyan
Postmortem vitreous bevacizumab levels of an infant treated for retinopathy of prematurity.
Tags: *Retinopathy of Prematurity, 2016, Angiogenesis Inhibitors, Antibodies, Bevacizumab/*analysis, Bouhenni Rachida, Department of Pharmaceutical Sciences, Gestational Age, Hanna Nancy, Hertle Richard W, Humanized, Humans, Hypes Stephen, Infant, Intravitreal Injections, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, Lawhon William, Monoclonal, Nasser Orwa, NEOMED College of Pharmacy, Newborn, Vascular Endothelial Growth Factor A, Vitreous Body/*chemistry
Development and validation of an LC-MS/MS method for determination of the L-type voltage-gated calcium channel/NMDA receptor antagonist NGP1-01 in mouse serum.
Tags: 2014, Anderson David J, Animals, Bridged-Ring Compounds/*blood, Calcium Channel Blockers/*blood, Chromatography, Crish Samuel D, Department of Pharmaceutical Sciences, Geldenhuys Werner J, Gobburi Ashta Lakshmi Prasad, Jogiraju Harini, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, LC-MS/MS, Limit of Detection, Liquid/*methods, Mice, Mouse serum, Multifunctional drug, N-Methyl-D-Aspartate/*antagonists & inhibitors, NEOMED College of Pharmacy, Neuroprotective agent, NGP1-01, Pedada Kiran K, Pentacycloundecylamine, Receptors, Reproducibility of Results, Tandem Mass Spectrometry/*methods, Van der Schyf Cornelis J, Zhou Xiang
Effect of ethanol on lipid metabolism.
Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation.
Tags: 2015, Animals, Aquaporin 4/*physiology, Aquaporin-4, Brain Edema/*drug therapy/pathology, Burke Jamie, Cerebral edema, Cerebrovascular Circulation/drug effects/physiology, Coughlin Lucy, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diiodothyronines/*administration & dosage, Erythropoietin, Infarction, Injections, Intravenous, Ischemic brain stroke, Journal of the neurological sciences, Male, Mdzinarishvili Alexander, Mice, Middle cerebral artery occlusion (MCAO), Middle Cerebral Artery/*drug therapy/pathology, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh, Stroke/*drug therapy/pathology, Thyroid hormone, Triiodothyronine/*administration & dosage, Woods Robert
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Anthocyanins/*therapeutic use, Anticarcinogenic Agents/therapeutic use, Apoptosis/drug effects, bcl-2-Associated X Protein/metabolism, Bishayee Anupam, Cell Proliferation/drug effects, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Down-Regulation, Experimental/metabolism/pathology, Folkesson Hans G, Haznagy-Radnai Erzsebet, Hohmann Judit, Liver Neoplasms, Liver Neoplasms/chemically induced/*prevention & control, Liver/pathology, Male, Mbimba Thomas, NEOMED College of Pharmacy, Phenobarbital, Plant Extracts/*therapeutic use, Proliferating Cell Nuclear Antigen/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Rats, Ribes/chemistry, Sipos Peter, Sprague-Dawley, The Journal of nutritional biochemistry, Thoppil Roslin J, Up-Regulation
Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.
Tags: *Atherosclerosis, *Farnesoid X receptor, *NAFLD, *Obesity, *TGR5, 2018, Adorini Luciano, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Jadhav Kavita, Kasumov Takhar, Lee Yoon-Kwang, Li Yuanyuan, Molecular metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Xu Jiesi, Xu Yang, Xu Yanyong, Yin Liya, Zhang Yanqiao, Zhu Yingdong
Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.
Tags: 2017, Alam Gelerah, Animals, Astrocytes/immunology/pathology, Beier Eric E, Cell Death/physiology, Corpus Striatum/immunology/pathology, Cytokines/metabolism, Department of Pharmaceutical Sciences, Disease Progression, Dopaminergic Neurons/*immunology/pathology, Edler Melissa, Inbred C57BL, Inflammation/pathology/physiopathology, Lipopolysaccharides/*toxicity, Male, Messenger/metabolism, Mice, Microglia/*immunology/pathology, Neal Matthew, NEOMED College of Pharmacy, Nerve Degeneration/*immunology/pathology, Neurobiology of disease, Neurodegenerative Diseases/immunology/pathology, Neuroimmunomodulation/physiology, Random Allocation, Richardson Jason R, RNA, Time Factors, Wu Long-Jun
Dimebon attenuates methamphetamine, but not MPTP, striatal dopamine depletion.
Tags: 2012, Animals, Corpus Striatum/*drug effects/metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Dluzen Dean E, Dopamine/*metabolism, Drug Synergism, Geldenhuys Werner J, Inbred C57BL, Indoles/*pharmacology, Methamphetamine/*pharmacology, Mice, NEOMED College of Pharmacy, Neurochemistry international
Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus.
Tags: *Brain injury, *Hippocampus, *Neural stem cells, *Neurogenesis, *Subventricular stem cells, *Trimethyltin, 2016, Amino Acids/metabolism, Animals, Brain Injuries/*pathology, Bromodeoxyuridine/metabolism, Cell Movement/*drug effects, Department of Pharmaceutical Sciences, Functional Laterality, Glial Fibrillary Acidic Protein/metabolism, Hippocampus/*pathology, Inbred C3H, Lateral Ventricles/drug effects/*pathology, Lowndes Herbert E, Male, Mice, NEOMED College of Pharmacy, Neurogenesis/drug effects/physiology, Neurotoxicology, Reuhl Kenneth R, Richardson Jason R, Trimethyltin Compounds/*toxicity, Weig Blair C
Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.
Tags: 2017, Animals, BDNF, Brain-Derived Neurotrophic Factor/metabolism, Cerebral Cortex/*drug effects/growth & development/metabolism, Corpus Striatum/*drug effects/growth & development/metabolism, Deltamethrin, Department of Pharmaceutical Sciences, Female, Inbred C57BL, Insecticides/*toxicity, Magby Jason P, Male, Messenger/metabolism, Mice, NEOMED College of Pharmacy, Neurodevelopmental, Neurons/*drug effects/metabolism, Neurotoxicology, Nitriles/*toxicity, Pregnancy, Prenatal Exposure Delayed Effects/*metabolism, Pyrethrins/*toxicity, Pyrethroid, Richardson Jason R, RNA, Sodium channel, Voltage-Gated Sodium Channels/*metabolism
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
The effect of manganese exposure in Atp13a2-deficient mice.
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Mice, *Parkinson's disease, *Sensorimotor function, 2018, Aga Diana S, Department of Pharmaceutical Sciences, Ekhator Osunde R, Fleming Sheila M, Holden John G, Karkare Swagata, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
Evidence of Wnt/beta-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.
Tags: *Alzheimer's disease, *Beta catenin, *Bone mineral density, *neurodegeneration, *Tauopathy, *Wnt proteins, *Wnt Signaling Pathway, 2018, Alzheimer Disease/*genetics/*metabolism, Animal, Animals, Ball Hope C, beta Catenin/metabolism, Bone and Bones/*metabolism, Bone Density, Bone Remodeling/genetics, Brain/*metabolism, Cooper Lisa Noelle, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Female, Gene Expression, Lin Li, Male, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Neurobiology of aging, Novak Kimberly M, Osteogenesis/genetics, Osteoporosis/etiology/genetics, tau Proteins/*metabolism, Tauopathies/genetics/*metabolism, Wnt Proteins/metabolism
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le
Relationships among gender, age, time, and temperature in methamphetamine-induced striatal dopaminergic neurotoxicity.
Tags: 2010, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Age Factors, Animals, Body Temperature/drug effects, Central Nervous System Stimulants/*toxicity, Corpus Striatum/*drug effects/metabolism, Darvesh A S, Department of Pharmaceutical Sciences, Dluzen D E, Dopamine/*metabolism, Female, In Vitro Techniques, Male, McDermott J L, Methamphetamine/*toxicity, Mice, NEOMED College of Pharmacy, Neuroscience, Neurotoxicity Syndromes/etiology/*metabolism/physiopathology, Sex Factors, Time Factors
Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms.
Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target.
Tags: 2013, Animal, Animals, Astrocytes/*metabolism, Axonal Transport/*physiology, Balaram P, Brain-Derived Neurotrophic Factor/*metabolism, Calkins D J, Crish S D, Dapper J D, Department of Pharmaceutical Sciences, Disease Models, Glaucoma/genetics/*metabolism, Lambert W S, MacNamee S E, Messenger/genetics/metabolism, Mice, NEOMED College of Pharmacy, Neuroscience, Optic Nerve Diseases/genetics/metabolism, Rats, Retinal Ganglion Cells/*metabolism, RNA, Sidorova T N, Superior Colliculi/metabolism, Synapses/*metabolism, Visual Pathways/metabolism
Nodes of Ranvier in Glaucoma.
Markers associated with testosterone enhancement of methamphetamine-induced striatal dopaminergic neurotoxicity.
Tags: 2012, Animals, Biomarkers/metabolism, Blotting, Body Temperature/drug effects, Body Weight/drug effects, Buletko A Blake, Corpus Striatum/*drug effects/metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Dluzen Dean E, Dopamine Plasma Membrane Transport Proteins/metabolism, Dopamine/*metabolism, Drug Synergism, Geldenhuys Werner J, HSP70 Heat-Shock Proteins/metabolism, Inbred Strains, Male, McDermott Janet L, Methamphetamine/*toxicity, Mice, NEOMED College of Pharmacy, Neurotoxicity Syndromes/*etiology/metabolism, Neurotoxicology and teratology, Oxidative Stress/drug effects, Testosterone Propionate/*pharmacology, Vesicular Monoamine Transport Proteins/metabolism, Western
Stable isotope-based flux studies in nonalcoholic fatty liver disease.
Tags: *Citric acid cycle, *Fatty acid oxidation, *Fibrosis, *NAFLD, *Oxidative Stress, *Stable isotopes, 2018, Animals, Department of Pharmaceutical Sciences, Humans, Isotopes/metabolism, Kasumov Takhar, Mass Spectrometry/*methods, McCullough Arthur, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*metabolism, Pharmacology & therapeutics, Previs Stephen
Ocular toxicity of AUY922 in pigmented and albino rats.
Tags: *AUY922, *Electroretinography, *Histopathology, *HSP90 inhibitor, *Ocular toxicity, *Rodents, 2016, Akimov Mikhail, Animals, Department of Pharmaceutical Sciences, Electroretinography, Eye/*drug effects/physiopathology, Isoxazoles/toxicity, Kluwe William, Lu Hong, Miller Paul E, NEOMED College of Pharmacy, Rats, Resorcinols/toxicity, Richardson Terrilyn A, Roman Danielle, Schadt Heiko, Toxicology and applied pharmacology, Turner Oliver, VerHoeve James, Vicart Axel, Walker Ursula Junker, Wistar, Wolford Suzanne T, Zhou Wei
Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.
Tags: 2018, Aleksunes Lauren M, Cytochrome b5, Department of Pharmaceutical Sciences, Free radicals, Fussell Karma C, Heck Diane E, Jan Yi-Hua, Laskin Debra L, Laskin Jeffrey D, Mishin Vladimir, NEOMED College of Pharmacy, reactive oxygen species, Redox cycling, Richardson Jason R, Szilagyi John T, Toxicology and applied pharmacology, Wang Yun, Yang Shaojun
Gaussian Process Modeling of Protein Turnover.
Tags: *Brain Chemistry, *dynamic proteome, *Gaussian process, *Mass spectrometry, *Ornstein-Uhlenbeck process, *protein degradation rate constant, *protein turnover rate constant, *stable isotope labeling, *stochastic differential equation for protein turnover rate constant, 2016, Animals, Chromatography, Data Interpretation, Department of Pharmaceutical Sciences, Isotope Labeling, Journal of proteome research, Kasumov Takhar, Kinetics, Liquid, Liver/*chemistry, Mass spectrometry, Mice, NEOMED College of Pharmacy, Normal Distribution, Previs Stephen F, Proteins/*metabolism, Proteome/*metabolism, Proteomics/methods, Rahman Mahbubur, Sadygov Rovshan G, Statistical, Stochastic Processes
d2ome, Software for in Vivo Protein Turnover Analysis Using Heavy Water Labeling and LC-MS, Reveals Alterations of Hepatic Proteome Dynamics in a Mouse Model of NAFLD.
Tags: 2018, 40S ribosomal proteins, Avva Jayant, Borzou Ahmad, Department of Pharmaceutical Sciences, Ilchenko Sergei, in vivo protein turnover, isotopomer quantification, Journal of proteome research, Kasumov Takhar, Lee Kwangwon, metabolic labeling, NAFLD, NEOMED College of Pharmacy, nonlinear least-squares modeling, peak detection and integration, protein half-life, Proteome dynamics, Rahman Mahbubur, Sadygov Rovshan G, UPR
MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.
Tags: *Aging, *Disease Models, *drug discovery, *mitochondrial dysfunction, *mitoNEET, 2017, ACS chemical neuroscience, Animal, Animals, Benkovic Stanley A, Brown Candice M, Corpus Striatum/*metabolism/*pathology, Crish Samuel D, Darvesh Altaf S, Department of Pharmaceutical Sciences, Geldenhuys Werner J, Inbred C57BL, Iron-Binding Proteins/genetics/*metabolism, Knockout, Lin Li, Male, Membrane Proteins/genetics/*metabolism, Mice, Mitochondria/*metabolism/*pathology, NEOMED College of Pharmacy, Parkinson Disease/*metabolism/pathology, Richardson Jason R, Sullivan Patrick G, Yonutas Heather M
Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4alpha and Protects Against Alcohol- and MCD diet-induced Liver Injury.
Tags: 2016, Alcoholic/*pathology, Alcohols/*toxicity, Animals, Carboxylic Ester Hydrolases/*metabolism, Chemical and Drug Induced Liver Injury/*pathology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Diet/*adverse effects, Fatty Liver, Gene Expression Regulation, Genetic, Hepatocyte Nuclear Factor 4/*metabolism, Hepatocytes/metabolism, Humans, Inbred C57BL, Jadhav Kavita, Knockout, Li Yuanyuan, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Promoter Regions, Protein Binding, Scientific reports, Xu Jiesi, Xu Yang, Yin Liya, You Min, Zhang Yanqiao
Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice.
Tags: 2016, Adiponectin/*blood, Alcoholic/blood/*genetics/metabolism, Animal, Animals, Chrast Roman, Department of Pharmaceutical Sciences, Disease Models, Fatty Liver, Fibroblast Growth Factors/*blood, Finck Brian N, Gene Knockout Techniques, Han Yoonhee, Hu Xudong, Jogasuria Alvin, Kim Chunki, Lipid Metabolism, Male, Mice, Myeloid Cells/*metabolism, NEOMED College of Pharmacy, NF-kappa B/metabolism, Nuclear Proteins/*deficiency, Organ Specificity, Phosphatidate Phosphatase/*deficiency, Scientific reports, Shen Hong, Signal Transduction, Wang Jiayou, Wu Jiashin, You Min
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.
Tags: 2016, Affo Silvia, Alcoholic/*immunology, Altamirano Jose, Animals, Arroyo Vicente, Bataller Ramon, Caballeria Juan, Cell Proliferation, Cells, Chen Jiegen, Collagen/genetics/metabolism, Common/*pathology, Crews Fulton, Cultured, Department of Pharmaceutical Sciences, Dumitru Raluca, Female, Gene Expression Profiling, Gene Expression Regulation, Gines Pere, Hepatic Duct, Hepatitis, Hepatocytes/*metabolism/pathology, Humans, Inbred BALB C, Keratins, Knockout, Lipopolysaccharides/metabolism, Lozano Juan Jose, Male, Matsushita Hiroshi, Mice, Middle Aged, Morales-Ibanez Oriol, NEOMED College of Pharmacy, Odena Gemma, Rautou Pierre-Emmanuel, Rodrigo-Torres Daniel, Sancho-Bru Pau, Scientific reports, Seki Ekihiro, Signal Transduction, Toll-Like Receptor 4/genetics/*metabolism, Type I/genetics/*metabolism, Valla Dominique, You Min, Zou Jian
The health benefits of blackcurrants.
Tags: *Health Promotion, *Ribes/chemistry, 2012, Ahmed Shamima, Anthocyanins/analysis, Anti-Infective Agents, Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Bishayee Anupam, Darvesh Altaf S, Department of Pharmaceutical Sciences, Fatty Acids, Flavonoids/analysis, Food & function, Fruit/chemistry, Gopalan Ashwin, Hohmann Judit, Humans, NEOMED College of Pharmacy, Phytogenic, Phytotherapy, Plant Extracts/adverse effects/pharmacokinetics/pharmacology, Reuben Sharon C, Unsaturated/analysis
Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model.
Tags: 2003, Administration, Angiogenesis Inducing Agents/*administration & dosage, Animal, Animals, Bulgrin Jeffery, College of Graduate Studies, Department of Pharmaceutical Sciences, Diabetes Mellitus/*physiopathology, Endothelial Growth Factors/*administration & dosage, Gruber Brian S, Intercellular Signaling Peptides and Proteins/*administration & dosage, Kirchner Loren M, Knoll Andrew K, Lymphokines/*administration & dosage, Meerbaum Sharon O, Mice, Models, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Schmidt Steven P, Taylor R A J, Topical, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors, Wound Healing/*drug effects, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis.
Tags: *adiponectin, *alcohol, *intestine, *iron, *liver injury, *Signal Transduction, 2016, Adiponectin/genetics/*metabolism, Alcoholic/genetics/*metabolism/pathology, Animals, Department of Pharmaceutical Sciences, Fatty Liver, Fibroblast Growth Factors/genetics/*metabolism, Han Yoonhee, Hu Xudong, Humans, Iron-Binding Proteins/metabolism, Jogasuria Alvin, Kim Chunki, Knockout, Male, Membrane Proteins/*deficiency/metabolism, Mice, NEOMED College of Pharmacy, NF-kappa B/genetics/metabolism, Shen Hong, Sirtuin 1/genetics/metabolism, The Journal of biological chemistry, Wang Jiayou, Wu Jiashin, You Min
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Tags: 2018, Allende Daniela, Borzou Ahmad, Dasarathy Srinivasan, Department of Pharmaceutical Sciences, Energy Metabolism, Haddad Andrew, Heavy water, Ilchenko Sergei, Kasumov Takhar, Kim Chunki, Lee Kwangwon, Mass spectrometry, McCullough Arthur, metabolic labeling, Mitochondria function or biology, Molecular & cellular proteomics : MCP, NEOMED College of Pharmacy, Osme Abdullah, oxidative phosphorylation, Oxidative Stress, Protein Degradation, Protein Turnover, Sadygov Rovshan G
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
Tags: *Anticarcinogenic Agents, 2013, Animal, Animals, Anti-Inflammatory Agents, Antioxidants, Biological Availability, Biological Markers, Bishayee Anupam, Carcinoma, Catechin/administration & dosage/analogs & derivatives, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Disease Models, Hepatocellular – Physiopathology, Hepatocellular – Prevention and Control, Hepatocellular – Therapy, Human, Humans, In Vitro Studies, In Vivo Studies, Liver Neoplasms/*drug therapy/*prevention & control, Mice, NEOMED College of Pharmacy, Neoplasms – Prevention and Control, nutrition, Nutrition and cancer, Outcomes (Health Care), Phenols – Therapeutic Use, Polyphenols/*administration & dosage/pharmacology, Tea – Therapeutic Use, Tea/*chemistry, Xenograft Model Antitumor Assays
Alpha 2-Adrenergic Receptor Agonist Brimonidine Stimulates ERK1/2 and AKT Signaling via Transactivation of EGF Receptors in the Human MIO-M1 Muller Cell Line.
Preparation of emulsifying wax/glyceryl monooleate nanoparticles and evaluation as a delivery system for repurposing simvastatin in bone regeneration.
Tags: 2018, Animals, Bone, Bone Regeneration/*drug effects/physiology, Czech Tori, Department of Pharmaceutical Sciences, Drug delivery, Drug Delivery Systems/*methods, Drug development and industrial pharmacy, Drug Evaluation, Drug Repositioning/methods, Emulsifying Agents/administration & dosage/*chemical synthesis, Eskinazi-Budge Aaron, Glycerides/administration & dosage/*chemical synthesis, Kunzler James, Manickavasagam Dharani, Mice, nanoemulsions, Nanoparticles, Nanoparticles/administration & dosage/*chemistry, NEOMED College of Pharmacy, Novak Kimberly, Osteoblasts, Osteoblasts/drug effects/physiology, Osteoclasts, Oyewumi Moses O, Preclinical/methods, RAW 264.7 Cells, Simvastatin/administration & dosage/*chemical synthesis, Waxes/chemical synthesis/pharmacology