A 44 y/o woman with PNH and aplastic anemia presented with 5 months of progressive painful purpuric nodules. Examination revealed firm, pink to purple, tender nodules in her lower and upper extremities and trunk. Biopsy revealed an edematous dermis,…
Patients with anhidrotic ectodermal dysplasia and immunodeficiency (EDA-ID)) have mutations in the gene on the X chromosome encoding nuclear factor kappa B (NF-kappa B) essential modulator (NEMO), resulting in conical teeth, sparse hair, anhidrosis…
Background: Psoriasis is a hyperproliferative and inflammatory skin disorder that affects roughly 2 percent of the worldwide population. Clobetasol propionate is the most common corticosteroid used to treat moderate-to-severe psoriasis but the…
Clinical situations that require the use of systemic antibiotic therapy are common. Because millions of women choose oral contraceptives for birth control, the potential for interaction between these drugs frequently has to be considered. We review…
Advanced wound care implies the use of products or procedures that are specialized. Although dermatologists are used to being specialists of the skin, hair, and nails, chronic wound care has evolved such that there are some specific treatment options…
Oral lichenoid lesions caused by hypersensitivity to mercury in amalgam fillings may mimic oral lichen planus on clinical and histologic examination. A positive patch test reaction to more than one mercurial allergen increases confidence in the…
Background: The use of drug samples is a controversial issue in medicine. Objective: We sought to determine the pros and cons of drug sampling, and how drug sampling in general medicine differs from dermatology. Methods: Literature searches were…
The use of drug samples in a dermatology clinic is controversial. Drug samples are associated with influencing physician prescribing patterns often toward costlier drugs, increasing health care costs, increasing waste, inducing potential conflicts of…
Erythema gyratum repens (EGR) is a rare and poorly understood dermatosis. The relationship of superficial dermatophytic infection to EGR-like eruptions in mycosis fungoides (MF) is unclear. We present a case of an EGR-like eruption in a patient with…
Pruritus is a common presenting diagnosis associated with a myriad of localized and systemic conditions. Due to many underlying causes, it can be challenging for the provider to assess. Symptoms often persist, causing frustration for the patient and…
