EVALUATION OF A COMMERCIALLY AVAILABLE CYTOMEGALOVIRUS-SPECIFIC IGM TEST FOR THE DIAGNOSIS OF CYTOMEGALOVIRUS-INFECTION IN THE SYMPTOMATIC NEWBORN
Infectious Diseases; Microbiology
Thomson R B; Benedict M L; Congeni B L
Diagnostic Microbiology and Infectious Disease
1987
1987-07
Journal Article
<a href="http://doi.org/10.1016/0732-8893(87)90007-1" target="_blank" rel="noreferrer noopener">10.1016/0732-8893(87)90007-1</a>
Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia
adults; assay binax; bacteremia; community-acquired pneumonia; diagnosis; etiologic diagnosis; infections; Infectious Diseases; management; Microbiology; pneumococcal pneumonia; rapid diagnosis; severity; sputum culture; Streptococcus pneumoniae; Urinary antigen
The Streptococcus pneumoniae (SP) urinary antigen (UAg) test is a commonly used assay. The purpose cif this study was to evaluate the test's actual performance in the clinical setting and determine the effects of renal function, grade of bacteremia, and severity-of-illness scores on its outcome. Patients with pneumococcal bacteremia were retrospectively identified and stratified on the basis of glomerular filtration rates, number of positive blood cultures, and CURB-65 scores. Logistic regression was used to determine the effect that these 3 variables had on test outcomes. SP UAg testing was performed in 65 of 129 patients with pneumococcal bacteremia and was positive in 42 of 65 (64.5%). Impaired renal function was the only variable to have a significant effect on test outcome (P = 0.03). Test performance was less sensitive than prospective studies indicate. Patients with impaired renal function were significantly more likely to have positive UAg tests. (C) 2010 Elsevier Inc. All rights reserved.
Selickman J; Paxos M; File T M; Seltzer R; Bonilla H
Diagnostic Microbiology and Infectious Disease
2010
2010-06
Journal Article
<a href="http://doi.org/10.1016/j.diagmicrobio.2010.01.005" target="_blank" rel="noreferrer noopener">10.1016/j.diagmicrobio.2010.01.005</a>