Centrally administered amphetamine (AMPH), cathinone, (CATH), or cocaine (COC) have each been shown to produce elevated activity in rats and this effect is dose responsive. The question remains whether these psychostimulants share a common mechanism…
Rats were trained to differentiate between the dopaminergically mediated discriminative stimuli produced by intraperitoneal administration of 4.8 mg/kg cathine and its vehicle. Once trained, three doses of l-fenfluramine (1.0, 2.0 and 2.5 mg/kg) were…