1
40
5
-
Text
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URL Address
<a href="http://doi.org/10.3109/03602532.2012.740048" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/03602532.2012.740048</a>
Pages
145–155
Issue
1
Volume
45
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Nuclear receptors in bile acid metabolism.
Publisher
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Drug metabolism reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-02
Subject
The topic of the resource
Humans; Animals; Biological Transport; Bile Acids and Salts/*metabolism; Xenobiotics/metabolism/pharmacology; Receptors; Cytoplasmic and Nuclear/genetics/*metabolism; Inactivation; Metabolic
Creator
An entity primarily responsible for making the resource
Li Tiangang; Chiang John Y L
Description
An account of the resource
Bile acids are signaling molecules that activate nuclear receptors, such as farnesoid X receptor, pregnane X receptor, constitutive androstane receptor, and vitamin D receptor, and play a critical role in the regulation of lipid, glucose, energy, and drug metabolism. These xenobiotic/endobiotic-sensing nuclear receptors regulate phase I oxidation, phase II conjugation, and phase III transport in bile acid and drug metabolism in the digestive system. Integration of bile acid metabolism with drug metabolism controls absorption, transport, and metabolism of nutrients and drugs to maintain metabolic homeostasis and also protects against liver injury, inflammation, and related metabolic diseases, such as nonalcoholic fatty liver disease, diabetes, and obesity. Bile-acid-based drugs targeting nuclear receptors are in clinical trials for treating cholestatic liver diseases and fatty liver disease.
Identifier
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<a href="http://doi.org/10.3109/03602532.2012.740048" target="_blank" rel="noreferrer noopener">10.3109/03602532.2012.740048</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2013
Animals
Bile Acids and Salts/*metabolism
Biological Transport
Chiang John Y L
Cytoplasmic and Nuclear/genetics/*metabolism
Department of Integrative Medical Sciences
Drug metabolism reviews
Humans
Inactivation
Li Tiangang
Metabolic
NEOMED College of Medicine
Receptors
Xenobiotics/metabolism/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3109/03602532.2013.754577" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/03602532.2013.754577</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-2
Issue
1
Volume
45
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Nuclear receptors in drug metabolism and beyond
Publisher
An entity responsible for making the resource available
Drug Metabolism Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-02
Subject
The topic of the resource
gene; Pharmacology & Pharmacy
Creator
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Xie W; Chiang J Y L
Identifier
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<a href="http://doi.org/10.3109/03602532.2013.754577" target="_blank" rel="noreferrer noopener">10.3109/03602532.2013.754577</a>
Format
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Journal Article
2013
Chiang J Y L
Drug metabolism reviews
gene
Journal Article
Pharmacology & Pharmacy
Xie W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
12-13
Volume
41
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Title
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Mechanism of FXR regulation of bile acid synthesis
Publisher
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Drug Metabolism Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
2009-10
Subject
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Pharmacology & Pharmacy
Creator
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Chiang J Y
Identifier
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n/a
Format
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Journal Article or Conference Abstract Publication
2009
Chiang J Y
Drug metabolism reviews
Journal Article or Conference Abstract Publication
Pharmacology & Pharmacy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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n/a
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Pages
16-16
Volume
39
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Title
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NUCLEAR RECEPTOR REGULATION OF BILE ACID AND DRUG METABOLISM
Publisher
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Drug Metabolism Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2007
2007
Subject
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Pharmacology & Pharmacy
Creator
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Chiang J Y; Li T G
Identifier
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n/a
Format
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Journal Article or Conference Abstract Publication
2007
Chiang J Y
Drug metabolism reviews
Journal Article or Conference Abstract Publication
Li T G
Pharmacology & Pharmacy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
33-33
Volume
36
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Dublin Core
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Title
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PXR regulation of bile acid synthesis and drug metabolism
Publisher
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Drug Metabolism Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-08
Subject
The topic of the resource
Pharmacology & Pharmacy
Creator
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Chiang J Y L; Li T
Identifier
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n/a
Format
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Journal Article or Conference Abstract Publication
2004
Chiang J Y L
Drug metabolism reviews
Journal Article or Conference Abstract Publication
Li T
Pharmacology & Pharmacy