Mitochondria are the center for oxidative phosphorylation, metabolism, and reactive oxygen species (ROS) production in the cell and home for several proapoptotic proteins. Therefore, tight regulation of mitochondrial health and function is essential…
ETHNOPHARMACOLOGICAL RELEVANCE: Cardiac hypertrophy is a key pathologic process in heart failure. Songling Xuemaikang Capsule (SXC), is a formulae of Chinese Medicine commonly used in China to treat hypertension and heart failure. However, its…
PURPOSE: Alpha 2-adrenergic receptor (alpha2-ADR) agonists are used clinically for a range of indications including reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Animal experiments show that…
