1 40 95 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1038/oby.2004.187" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/oby.2004.187</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 1499-1508 Issue 9 Volume 12 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Longitudinal Relationship Between Elapsed Time In The Action Stages Of Change And Weight Loss Publisher An entity responsible for making the resource available Obesity Research Date A point or period of time associated with an event in the lifecycle of the resource 2004 2004-09 Subject The topic of the resource balance; decisional; Endocrinology & Metabolism; exercise; health behaviors; longitudinal study; Nutrition & Dietetics; obesity; physical-activity; primary care; primary care; reducing dietary-fat; self-efficacy; transtheoretical model; weight loss; women Creator An entity primarily responsible for making the resource Logue E E; Jarjoura D G; Sutton K S; Smucker W D; Baughman K R; Capers C F Description An account of the resource Objective: The objective of this study was to examine the longitudinal relationship between the elapsed time in the action and maintenance stages of change for multiple target behaviors and weight loss or gain. Research Methods and Procedures: The research design was a prospective cohort study of overweight and obese primary care patients randomized to an obesity management intervention based on the Transtheoretical Model and a chronic disease paradigm. The target behaviors included increased planned exercise and usual physical activity, decreased dietary fat, increased fruit and vegetable consumption, and increased dietary portion control. The participants were 329 middle-aged men and women with elevated body mass indices recruited from 15 primary care practices in Northeastern Ohio; 28% of the participants were African Americans. The main outcomes were weight loss (5% or more) or weight gain (5% or more) after 18 or 24 months of follow-up. Results: There were significant (p < 0.05) longitudinal relationships between the number of periods (0 to 4) in action or maintenance for each of the five target behaviors, or a composite score taken across the five target behaviors, and weight loss. In all cases, there was a significant (p < 0.05) stepped (graded) relationship between the time in action or maintenance and weight loss (or gain). Discussion: The data support the concept of applying the Transtheoretical Model to the problem of managing obesity in primary care settings. The remaining challenge is to identify those factors that reliably move patients into the action and maintenance stages for long periods. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1038/oby.2004.187" target="_blank" rel="noreferrer noopener">10.1038/oby.2004.187</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2004 Balance Baughman K R Capers C F decisional Department of Family & Community Medicine Endocrinology & Metabolism Exercise health behaviors Jarjoura D G Journal Article or Conference Abstract Publication Logue E E longitudinal study NEOMED College of Medicine Nutrition & Dietetics Obesity Obesity Research physical-activity primary care reducing dietary-fat self-efficacy Smucker W D Sutton K S transtheoretical model Weight Loss Women Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1038/oby.2005.106" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/oby.2005.106</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 917-927 Issue 5 Volume 13 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transtheoretical Model-chronic Disease Care For Obesity In Primary Care: A Randomized Trial Publisher An entity responsible for making the resource available Obesity Research Date A point or period of time associated with an event in the lifecycle of the resource 2005 2005-05 Subject The topic of the resource chronic disease; clinical-trials; cognitive-behavioral therapy; dietary-fat intake; Endocrinology & Metabolism; exercise behavior; intervention; motivational readiness; Nutrition & Dietetics; physical-activity; program; randomized controlled trial; self-efficacy; services task-force; treatment; weight management; weight loss Creator An entity primarily responsible for making the resource Logue E E; Sutton K; Jarjoura D; Smucker W; Baughman K; Capers C Description An account of the resource Objective: To compare health benefits achieved in a transtheoretical model-chronic disease (TM-CD) minimal intervention for obesity vs. augmented usual care (AUC). Research Method and Procedures: This was a 2-year, randomized clinical trial with overweight or obese men and women from 15 primary care sites. AUC (n = 336) included dietary and exercise advice, prescriptions, and three 24-hour dietary recalls every 6 months. TM-CD care (n = 329) included AUC elements plus "stage of change" (SOC) assessments for five target behaviors every other month, mailed SOC and target behavior-matched-workbooks, and monthly telephone calls from a weight-loss advisor. Weight change was the primary outcome. Results: Repeated measures models under the missing at random assumption yielded nonsignificant adjusted differences between. the AUC and TM-CD groups for weight change, waist circumference, energy intake or expenditure, blood pressure, and blood lipids. The pattern of change over time suggested that TM-CD participants were trying harder to impact target behaviors during the first 6 to 12 months of the trial but relapsed afterward. Sixty percent of trial participants maintained their baseline weights for 18 to 24 months. Discussion: A combination of mailed patient materials and monthly telephone calls based on, the transtheoretical model and some elements of chronic disease care is not powerful enough, relative to AUC, to alter target behaviors among overweight primary care patients in an obesogenic environment. AUC may be sufficient to maintain weights among at-risk primary care patients. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1038/oby.2005.106" target="_blank" rel="noreferrer noopener">10.1038/oby.2005.106</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2005 Baughman K Capers C Chronic Disease clinical-trials cognitive-behavioral therapy Department of Family & Community Medicine dietary-fat intake Endocrinology & Metabolism exercise behavior Intervention Jarjoura D Journal Article or Conference Abstract Publication Logue E E motivational readiness NEOMED College of Medicine Nutrition & Dietetics Obesity Research physical-activity program randomized controlled trial self-efficacy services task-force Smucker W Sutton K Treatment Weight Loss weight management Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.ygcen.2012.07.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ygcen.2012.07.011</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 562-572 Issue 3 Volume 178 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Knockdown Of Leptin A Expression Dramatically Alters Zebrafish Development Publisher An entity responsible for making the resource available General and Comparative Endocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2012 2012-09 Subject The topic of the resource atlantic salmon; Auditory; bhlh genes; bone; carp cyprinus-carpio; cell fate specification; central-nervous-system; cloning; danio-rerio; differentiation; Endocrinology & Metabolism; gene; metabolism; n-cadherin; receptor; sensory ganglia; Visual; visual-system Creator An entity primarily responsible for making the resource Liu Q; Dalman M; Chen Y; Akhter M; Brahmandam S; Patel Y; Lowe J; Thakkar M; Gregory A V; Phelps D; Riley C; Londraville R L Description An account of the resource Using morpholino antisense oligonucleotide (MO) technology, we blocked leptin A or leptin receptor expression in embryonic zebrafish, and analyzed consequences of leptin A knock-down on fish development. Embryos injected with leptin A or leptin receptor MOs (leptin A or leptin receptor morphants) had smaller bodies and eyes, undeveloped inner ear, enlarged pericardial cavity, curved body and/or tail and larger yolk compared to control embryos of the same stages. The defects persisted in 6-9 days old larvae. We found that blocking leptin A function had little effect on the development of early brain (1 day old), but differentiation of both the morphant dorsal brain and retinal cells was severely disrupted in older (2 days old) embryos. Despite the enlarged pericardial cavity, differentiation of cardiac cells appeared to be similar to control embryos. Formation of the morphants' inner ear is also severely disrupted, which corroborates existing reports of leptin receptor expression in inner ear of both zebrafish and mammals. Co-injection of leptin A MO and recombinant leptin results in partial rescue of the wild-type phenotype. Our results suggest that leptin A plays distinct roles in zebrafish development. (c) 2012 Elsevier Inc. All rights reserved. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.ygcen.2012.07.011" target="_blank" rel="noreferrer noopener">10.1016/j.ygcen.2012.07.011</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2012 Akhter M atlantic salmon Auditory bhlh genes Bone Brahmandam S carp cyprinus-carpio cell fate specification central-nervous-system Chen Y Cloning Dalman M danio-rerio differentiation Endocrinology & Metabolism gene General and Comparative Endocrinology Gregory A V Journal Article or Conference Abstract Publication Liu Q Londraville R L Lowe J Metabolism n-cadherin Patel Y Phelps D Receptor Riley C sensory ganglia Thakkar M Visual visual-system Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 1-1 Issue 3 Volume 31 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Role Of The Orphan Nuclear Receptor Shp In Diet-induced Obesity And Diabetes Publisher An entity responsible for making the resource available Endocrine Reviews Date A point or period of time associated with an event in the lifecycle of the resource 2010 2010-06 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Lee Y K; Park Y J; Moore D D Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2010 Endocrine reviews Endocrinology & Metabolism Journal Article or Conference Abstract Publication Lee Y K Moore D D Park Y J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.2337/diacare.7.6.590" target="_blank" rel="noreferrer noopener">http://doi.org/10.2337/diacare.7.6.590</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 590-594 Issue 6 Volume 7 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Potential Pitfalls In The Use Of Glucoscan And Glucoscan Ii Meters For Self-monitoring Of Blood-glucose Publisher An entity responsible for making the resource available Diabetes Care Date A point or period of time associated with an event in the lifecycle of the resource 1984 1984 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Laus V G; Dietz M A; Levy R P Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.2337/diacare.7.6.590" target="_blank" rel="noreferrer noopener">10.2337/diacare.7.6.590</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1984 Diabetes Care Dietz M A Endocrinology & Metabolism Journal Article or Conference Abstract Publication Laus V G Levy R P Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S206-S206 Volume 15 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Gene Expression Of Isolated Individual Chondrocytes From Growth Plate Cartilage Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2000 2000-09 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Landis W J; Zhang J; Jacquet R Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2000 Endocrinology & Metabolism Jacquet R Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research Landis W J Zhang J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S236-S236 Volume 16 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Function Of Osteopontin Deduced From Laser Capture Microdissection And Rt/pcr Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2001 2001-09 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Landis W J; Jacquet R; Hillyer J; Zhang J Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2001 Endocrinology & Metabolism Hillyer J Jacquet R Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research Landis W J Zhang J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1359/jbmr.2000.15.6.1099" target="_blank" rel="noreferrer noopener">http://doi.org/10.1359/jbmr.2000.15.6.1099</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 1099-1112 Issue 6 Volume 15 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Spaceflight Effects On Cultured Embryonic Chick Bone Cells Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2000 2000-06 Subject The topic of the resource biomechanics; bone adaptation; collagen; differentiation; Endocrinology & Metabolism; in-vitro; mechanical strain; messenger-rna expression; microgravity; osteoblast; osteoblasts; osteopontin; restriction; signal-transduction; space-flight Creator An entity primarily responsible for making the resource Landis W J; Hodgens K J; Block D; Toma C D; Gerstenfeld L C Description An account of the resource A model calcifying system of primary osteoblast cell cultures derived from normal embryonic chicken calvaria has been flown aboard the shuttle, Endeavour, during the National Aeronautics and Space Administration (NASA) mission STS-59 (April 9-20, 1994) to characterize unloading and other spaceflight effects on the bone cells. Aliquots of cells (similar to 7 x 10(6)) grown in Dulbecco's modified Eagle's medium (DMEM) + 10% fetal bovine serum (FBS) were mixed with microcarrier beads, inoculated into cartridge culture units of artificial hollow fiber capillaries, and carried on the shuttle. To promote cell differentiation, cartridge media were supplemented with 12.5 mu g/ml ascorbate and 10 mM P-glycerophosphate for varying time periods before and during Right. Four cartridges contained cells from 17-day-old embryos grown for 5 days in the presence of ascorbate prior to launch (defined as flight cells committed to the osteoblastic lineage) and four cartridges supported cells from 14-day-old embryos grown for 10 days with ascorbate before launch (uncommitted flight cells). Eight cartridges prepared in the same manner were maintained under normal gravity throughout the Right (control cells) and four additional identical cartridges under normal gravity were terminated on the day of launch (basal cells). From shuttle launch to landing, all cartridges were contained in closed hardware units maintaining 5% CO2, 37 degrees C, and media delivery at a rate of similar to 1.5 ml/6 h. During day 3 and day 5 of flight, duplicate aliquots of conditioned media and accumulated cell products were collected in both the Right and the control hardware units. At the mission end, comparisons among Right, basal, and control samples were made in cell metabolism gene expression for type I collagen and osteocalcin, and ultrastructure. Both committed and uncommitted flight cells were metabolically active, as measured by glucose uptake and lactate production, at approximately the same statistical levels as control counterparts. Flight cells elaborated a less extensive extracellular matrix, evidenced by a reduced collagen gene expression and collagen protein appearance compared with controls. Osteocalcin was expressed by all cells, a result indicating progressive differentiation of both flight and control osteoblasts, but its message levels also were reduced in flight cells compared with ground samples. This finding suggested that osteoblasts subjected to flight followed a slower progression toward a differentiated function. The summary of data indicates that spaceflight, including microgravity exposure, demonstrably affects bone cells by down-regulating type I collagen and osteocalcin gene expression and thereby inhibiting expression of the osteogenic phenotype notably by committed osteoblasts. The information is important for insight into the response of bone cells to changes of gravity and of force in general. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1359/jbmr.2000.15.6.1099" target="_blank" rel="noreferrer noopener">10.1359/jbmr.2000.15.6.1099</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2000 biomechanics Block D Bone adaptation Collagen differentiation Endocrinology & Metabolism Gerstenfeld L C Hodgens K J in-vitro Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research Landis W J mechanical strain messenger-rna expression microgravity OSTEOBLAST Osteoblasts Osteopontin restriction signal-transduction space-flight Toma C D Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S331-S331 Volume 18 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Growth Hormone Expressed In Erythroid Marrow Is Osteogenic In Transgenic Mice In The Absence Of Local Igf-i Induction Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2003 2003-09 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Kunes J R; Sparks S E; King D Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2003 Endocrinology & Metabolism Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research King D Kunes J R Sparks S E Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S527-S527 Volume 12 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Gene Therapy Strategy To Improve Bone Quality In Osteogenesis Imperfecta Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 1997 1997-08 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource King D; Beamer W; Chase J; Havey R; Patwardhan A; Saban J; Schneider G; Sparks S E; Steinke B; Zussman M Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1997 Beamer W Chase J Endocrinology & Metabolism Havey R Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research King D Patwardhan A Saban J Schneider G Sparks S E Steinke B Zussman M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/osp4.309" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/osp4.309</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 36-45 Issue 1 Volume 5 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Systematic Review: The Appraisal Of The Effects Of Metformin On Lipoprotein Modification And Function Publisher An entity responsible for making the resource available Obesity Science & Practice Date A point or period of time associated with an event in the lifecycle of the resource 2019 2019-02 Subject The topic of the resource a-i; cardiovascular-disease; cholesterol; Endocrinology & Metabolism; expression; glycation end-products; Gycation; high-density-lipoprotein; increases; Lipoproteins; metformin; methylglyoxal; oxidative stress; Type II diabetes; type-2 Creator An entity primarily responsible for making the resource Kheniser K G; Kashyap S R; Kasumov T Description An account of the resource Aims Metformin is a commonly prescribed anti-hyperglycaemic pharmacological agent, and it remains a staple in the management of type II diabetes. In addition to metformin's glucose lowering effects, research has indicated that metformin inhibits glycation-mediated and oxidative modification of lipoprotein residues. The purpose was to discuss the effects of metformin as it relates to high-density lipoprotein (HDL) and low-density lipoprotein (LDL) modification. Materials and methods The purpose was to conduct a narrative and pragmatic review on the effects of metformin as it pertains to HDL and LDL modification. Results High-density lipoprotein (HDL) concentration is a quantitative measure and therefore does not provide insight into its function, which is a qualitative property. Dysfunctional HDLs are unable to carry out functions normally associated with HDL because they can be modified by glycating agents. Metformin may counteract HDL dysfunction by abating HDL modification. Reductions in HDL modification may improve reverse cholesterol transport ability and thus possibly diminish cardiovascular risk. Similarly, metformin-mediated attenuations in LDL modification may reduce their atherogenic potency. Conclusion Metformin may partially ameliorate HDL dysfunction and reduce LDL modification by inhibiting alpha-dicarbonyl-mediated modification of apolipoprotein residues; consequently, the results are salient because cardiovascular disease incidence may be reduced given that reverse cholesterol transport activity predicts risk, and modified LDL are proatherogenic. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/osp4.309" target="_blank" rel="noreferrer noopener">10.1002/osp4.309</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2019 a-i cardiovascular-disease Cholesterol Department of Pharmaceutical Sciences Endocrinology & Metabolism expression glycation end-products Gycation high-density-lipoprotein increases Journal Article or Conference Abstract Publication Kashyap S R Kasumov T Kheniser K G Lipoproteins metformin methylglyoxal NEOMED College of Pharmacy Obesity science & practice Oxidative Stress Type II diabetes type-2 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.freeradbiomed.2017.10.300" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.freeradbiomed.2017.10.300</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 191-191 Volume 112 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Pleiotropic Roles Of Nrf2 As Regulators Of Chondrocyte Apoptosis, Oxidative Stress, Inflammatory Response And Catabolic And Anabolic Pathways In Osteoarthritis Publisher An entity responsible for making the resource available Free Radical Biology and Medicine Date A point or period of time associated with an event in the lifecycle of the resource 2017 2017-11 Subject The topic of the resource Biochemistry & Molecular Biology; Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Khan N M; Haqqi T M Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.freeradbiomed.2017.10.300" target="_blank" rel="noreferrer noopener">10.1016/j.freeradbiomed.2017.10.300</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2017 Biochemistry & Molecular Biology Endocrinology & Metabolism Free Radical Biology and Medicine Haqqi T M Journal Article or Conference Abstract Publication Khan N M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.freeradbiomed.2017.10.170" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.freeradbiomed.2017.10.170</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 113-114 Volume 112 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Increased Cysteine Sulfonation Of The Hydrophilic Domain Of Complex I Mediates Mitochondrial Dysfunction In The Post-ischemic Heart Publisher An entity responsible for making the resource available Free Radical Biology and Medicine Date A point or period of time associated with an event in the lifecycle of the resource 2017 2017-11 Subject The topic of the resource Biochemistry & Molecular Biology; Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Kang P T; Chen C L; Lin P; Zhang L W; Chen Y R Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.freeradbiomed.2017.10.170" target="_blank" rel="noreferrer noopener">10.1016/j.freeradbiomed.2017.10.170</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2017 Biochemistry & Molecular Biology Chen C L Chen Y R Department of Family & Community Medicine Endocrinology & Metabolism Free Radical Biology and Medicine Journal Article or Conference Abstract Publication Kang P T Lin P NEOMED College of Medicine Zhang L W Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.molmet.2017.08.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.molmet.2017.08.011</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 1517-1528 Issue 11 Volume 6 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Decreasing Cb1 Receptor Signaling In Kupffer Cells Improves Insulin Sensitivity In Obese Mice Publisher An entity responsible for making the resource available Molecular Metabolism Date A point or period of time associated with an event in the lifecycle of the resource 2017 2017-11 Subject The topic of the resource adiponectin receptors; adipose-tissue; CB1 receptors; disruption; endocannabinoid system; Endocrinology & Metabolism; fatty liver-disease; Inflammation; Insulin resistance; Kupffer cells; macrophage polarization; nf-kappa-b; nonalcoholic steatohepatitis; protein-2; reactive oxygen; siRNA; targeted; uncoupling Creator An entity primarily responsible for making the resource Jourdan T; Nicoloro S M; Zhou Z; Shen Y F; Liu J; Coffey N J; Cinar R; Godlewski G; Gao B; Aouadi M; Czech M P; Kunos G Description An account of the resource Objective: Obesity-induced accumulation of ectopic fat in the liver is thought to contribute to the development of insulin resistance, and increased activity of hepatic CB1R has been shown to promote both processes. However, lipid accumulation in liver can be experimentally dissociated from insulin resistance under certain conditions, suggesting the involvement of additional mechanisms. Obesity is also associated with pro-inflammatory changes which, in turn, can promote insulin resistance. Kupffer cells (KCs), the liver's resident macrophages, are the major source of pro-inflammatory cytokines in the liver, such as TNF-alpha, which has been shown to inhibit insulin signaling in multiple cell types, including hepatocytes. Here, we sought to identify the role of CB1R in KCs in obesity-induced hepatic insulin resistance. Methods: We used intravenously administered beta-D-glucan-encapsulated siRNA to knock-down CB1R gene expression selectively in KCs. Results: We demonstrate that a robust knock-down of the expression of Cnr1, the gene encoding CB1R, results in improved glucose tolerance and insulin sensitivity in diet-induced obese mice, without affecting hepatic lipid content or body weight. Moreover, Cnr1 knock-down in KCs was associated with a shift from pro-inflammatory M1 to anti-inflammatory M2 cytokine profile and improved insulin signaling as reflected by increased insulin-induced Akt phosphorylation. Conclusion: These findings suggest that CB1R expressed in KCs plays a critical role in obesity-related hepatic insulin resistance via a pro inflammatory mechanism. Published by Elsevier GmbH. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.molmet.2017.08.011" target="_blank" rel="noreferrer noopener">10.1016/j.molmet.2017.08.011</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2017 adiponectin receptors adipose-tissue Aouadi M cb1 receptors Cinar R Coffey N J Czech M P disruption endocannabinoid system Endocrinology & Metabolism fatty liver-disease Gao B Godlewski G Inflammation Insulin Resistance Jourdan T Journal Article or Conference Abstract Publication Kunos G Kupffer cells Liu J macrophage polarization Molecular metabolism nf-kappa-b Nicoloro S M Nonalcoholic steatohepatitis protein-2 Reactive oxygen Shen Y F siRNA targeted uncoupling Zhou Z Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1210/en.2004-0487" target="_blank" rel="noreferrer noopener">http://doi.org/10.1210/en.2004-0487</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 4330-4343 Issue 9 Volume 145 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Gonadal Hormones And Frontocortical Expression Of Vascular Endothelial Growth Factor In Male Stroke-prone, Spontaneously Hypertensive Rats, A Model For Attention-deficit/hyperactivity Disorder Publisher An entity responsible for making the resource available Endocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2004 2004-09 Subject The topic of the resource aged female rats; animal-model; central-nervous-system; cerebral-blood-flow; computed tomography; deficit-hyperactivity-disorder; emission; Endocrinology & Metabolism; estrogen-receptor-alpha; in-situ hybridization; insulin-resistant; messenger-ribonucleic-acid; stage Creator An entity primarily responsible for making the resource Jesmin S; Togashi H; Sakuma I; Mowa C N; Ueno K I; Yamaguchi T; Yoshioka M; Kitabatake A Description An account of the resource Attention-deficit/hyperactivity disorder (AD/HD) is a common pediatric behavioral disorder associated, in part, with male preponderance and reduced regional cerebral blood flow (rCBF). However, mechanism(s) underlying male preponderance and reduced rCBF in AD/HD are unclear. The present study profiles the expression of angiogenic and hormonal factors likely to underlie these symptoms using a recently characterized AD/HD animal model, juvenile male stroke-prone spontaneously hypertensive rats (SHRSP). Because vascular endothelial growth factor (VEGF) signaling cascade and gonadal steroids are key regulators of angiogenesis and gender-based behavior, respectively, we profiled their patterns of expression in the frontal cortex of SHRSP to elucidate their roles in the genesis of AD/HD male preponderance and rCBF. Interestingly, levels of VEGF, VEGF receptors (KDR, Flt-1), endothelial nitric oxide synthase, phosphorylated. Akt (pAkt), estrogen receptor-alpha, aromatase, and capillary density in sham-operated SHRSP were remarkably down-regulated, whereas androgen receptor levels were up-regulated, compared with age-matched genetic control, Wistar-Kyoto rats. Castration, estrogen, and androgen receptor antagonist (flutamide) counteracted these effects. Dihydrotestosterone, but not testosterone, reversed the beneficiary effects of castration. Estrogen receptor-beta levels remained unchanged in all groups examined. We postulate that changes in androgen metabolism that tend to up-regulate local dihydrotestosterone concentration and diminish estrogen synthesis, in the frontal cortex of juvenile male SHRSP, may lower levels and/or activity of VEGF and its signaling cascade and, subsequently, reduce rCBF. These findings could, in part, help explain the pathogenesis of reduced rCBF and male preponderance in AD/HD. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1210/en.2004-0487" target="_blank" rel="noreferrer noopener">10.1210/en.2004-0487</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2004 aged female rats animal-model central-nervous-system cerebral-blood-flow computed tomography deficit-hyperactivity-disorder emission Endocrinology Endocrinology & Metabolism estrogen-receptor-alpha in-situ hybridization insulin-resistant Jesmin S Journal Article or Conference Abstract Publication Kitabatake A messenger-ribonucleic-acid Mowa C N Sakuma I stage Togashi H Ueno K I Yamaguchi T Yoshioka M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1677/jme.101548" target="_blank" rel="noreferrer noopener">http://doi.org/10.1677/jme.101548</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 343-359 Issue 2 Volume 33 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Aromatase Is Abundantly Expressed By Neonatal Rat Penis But Downregulated In Adulthood Publisher An entity responsible for making the resource available Journal of Molecular Endocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2004 2004-10 Subject The topic of the resource androgen receptor; beta messenger-rnas; brain; cytochrome-p450 aromatase; Endocrinology & Metabolism; estrogen-receptor-alpha; female reproductive organ; in-situ hybridization; leydig-cells; ribonucleic-acid; tract Creator An entity primarily responsible for making the resource Jesmin S; Mowa C N; Sakuma I; Matsuda N; Togashi H; Yoshioka M; Hattori Y; Kitabatake A Description An account of the resource Although synthesis of estrogen by male gonads has been well documented for over half a century, it is only recently that the role of estrogen in male reproductive events has gained appreciation. We recently reported abundant expression of estrogen receptor (ER)-alpha and -beta in different cell types of the rat penis, whose levels diminished with advancing age. The present study, which builds on data from the ER study, was designed to determine whether the penis is capable of generating its own local estrogen by examining evidence of the expression of aromatase, a microsomal enzymatic complex which irreversibly converts androgens to estrogens, using immunohistochemistry, Western blotting, in situ hybridization and real-time PCR analyses. Secondly, the effects of sex steroid hormones on penile aromatase were examined. Discrete aromatase immunoreactive cells were localized in primordial corpus cavernosum, corpus spongiosus and os penis, blood vessels and sensory corpuscle of glans penis. In situ hybridization signals corresponded with immunohistochemical findings. Western blot, enzyme immunoassay and real-time PCR analyses of rat penile samples revealed an age-dependent expression of aromatase and estrogen, with levels at week 1 almost resembling those of the ovary, but they decreased sharply by week 8, and decreased further by week 35. This expression pattern was strikingly similar to that of ER-alpha reported previously. Testosterone and diethylstilbesterol administered prenatally upregulate levels of aromatase mRNA and protein, and estrogen postnatally. Dihydrotestosterone upregulated aromatase mRNA and protein, but not estrogen. We conclude that estrogen acts via ER in a paracrine and/or autocrine manner to regulate penile events, particularly during development, and that estrogen synthesis is regulated by estrogen and androgens. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1677/jme.101548" target="_blank" rel="noreferrer noopener">10.1677/jme.101548</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2004 androgen receptor beta messenger-rnas Brain cytochrome-p450 aromatase Endocrinology & Metabolism estrogen-receptor-alpha female reproductive organ Hattori Y in-situ hybridization Jesmin S Journal Article or Conference Abstract Publication Journal of Molecular Endocrinology Kitabatake A leydig-cells Matsuda N Mowa C N ribonucleic-acid Sakuma I Togashi H tract Yoshioka M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1210/en.2002-220628" target="_blank" rel="noreferrer noopener">http://doi.org/10.1210/en.2002-220628</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 4764-4774 Issue 12 Volume 143 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evidence For A Potential Role Of Estrogen In The Penis: Detection Of Estrogen Receptor-alpha And -beta Messenger Ribonucleic Acid And Protein Publisher An entity responsible for making the resource available Endocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2002 2002-12 Subject The topic of the resource androgen receptor; differential expression; dorsal-root ganglion; Endocrinology & Metabolism; hyena crocuta-crocuta; in-situ hybridization; male reproductive-system; molecular-cloning; rat pituitary; sexual-behavior; spinal-cord Creator An entity primarily responsible for making the resource Jesmin S; Mowa C N; Matsuda N; Salah-Eldin A E; Togashi H; Sakuma I; Hattori Y; Kitabatake A Description An account of the resource Body tissues are traditionally classified as estrogen targets based on both the response to the hormone and the presence of estrogen receptors (ERs). We undertook the study on expression of ERalpha and ERbeta in the penis to identify compartments/cells responsive to estrogen, using immunohistochemistry, Western blotting, in situ hybridization, and RT-PCR analyses. Expressions of ERalpha and ERbeta in the rat penis were age dependent at both mRNA and protein levels, with the most intense signals being observed during the perinatal period and declining thereafter with age. Initial signals (fetal d 17) of ERalpha were localized to the mesenchyme and subepithelial stroma and later (postnatal d 2) to the corpus spongiosus, corpus cavernosus; and urethral epithelia. ERbeta was initially detected by postnatal d 2 and was localized diffusely in corpus spongiosus and cavernosus in immature rats. In the. adult, both ERs were concentrated largely to the urethral eithelia and vascular and neuronal structures. The present study provides the first evidence for ER expression in the penis. Thus, our data add the penis to the list of estrogen-responsive tissues in males and provide a base and insight for future studies aimed at investigating a functional role of estrogen in the penis, especially in development. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1210/en.2002-220628" target="_blank" rel="noreferrer noopener">10.1210/en.2002-220628</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2002 androgen receptor differential expression dorsal-root ganglion Endocrinology Endocrinology & Metabolism Hattori Y hyena crocuta-crocuta in-situ hybridization Jesmin S Journal Article or Conference Abstract Publication Kitabatake A male reproductive-system Matsuda N molecular-cloning Mowa C N rat pituitary Sakuma I Salah-Eldin A E sexual-behavior spinal-cord Togashi H Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.yfrne.2006.03.034" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.yfrne.2006.03.034</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 16-16 Issue 1 Volume 27 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Testosterone And Estrogen Influence Collagen Type I Production In Coronary Artery And Aortic Fibroblasts Publisher An entity responsible for making the resource available Frontiers in Neuroendocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2006 2006-05 Subject The topic of the resource Endocrinology & Metabolism; Neurosciences & Neurology Creator An entity primarily responsible for making the resource Jenkins C; Milsted A; Doane K; Meszaros G; Ely D Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.yfrne.2006.03.034" target="_blank" rel="noreferrer noopener">10.1016/j.yfrne.2006.03.034</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2006 Doane K Ely D Endocrinology & Metabolism Frontiers in Neuroendocrinology Jenkins C Journal Article or Conference Abstract Publication Meszaros G Milsted A Neurosciences & Neurology Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S232-S233 Volume 32 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Gpnmb/osteoactivin Plays A Novel Role In Autophagy-mediated Osteoclast Differentiation And Function Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2017 2017-12 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Jaber F; Al-Adlaan A; Hussein N; Safadi F Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2017 Al-Adlaan A Endocrinology & Metabolism Hussein N Jaber F Journal Article or Conference Abstract Publication Journal of Bone and Mineral Research Safadi F Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.bone.2007.06.024" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.bone.2007.06.024</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 535-542 Issue 4 Volume 41 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Type Xxvii Collagen At The Transition Of Cartilage To Bone During Skeletogenesis Publisher An entity responsible for making the resource available Bone Date A point or period of time associated with an event in the lifecycle of the resource 2007 2007-10 Subject The topic of the resource bone; cartilage; chondrocyte; col27a1; COL27Al; endochondral; Endocrinology & Metabolism; expression; forms; gene; growth-plate; ix; skeletogenesis; type X-XVII collagen; vertebrate fibrillar collagen; xi Creator An entity primarily responsible for making the resource Hjorten R; Hansen U; Underwood R A; Telfer H E; Fernandes R J; Krakow D; Sebald E; Wachsmann-Hogiu S; Bruckner P; Jacquet R; Landis W J; Byers P H; Pace J M Description An account of the resource COL27A1 is a member of the collagen fibrillar gene family and is expressed in cartilaginous tissues including the anlage of endochondral bone. To begin to understand its role in skeletogenesis, the temporospatial distributions of its RNA message and protein product, type XXVII collagen, were determined in developing human skeletal tissues. Laser capture microdissection and quantitative reverse-transcription polymerase chain reaction demonstrated that gene expression occurred throughout the growth plate and that it was higher in the resting and proliferative zones than in hypertrophic cartilage. Immunohistochemical analyses showed that type XXVII collagen was most evident in hypertrophic cartilage at the primary ossification center and at the growth plate and that it accumulated in the pericellular matrix. Synthesis of type XXVII collagen overlapped partly with that of type X collagen, a marker of chondrocyte hypertrophy, preceded the transition of cartilage to bone, and was associated with cartilage calcification. Immunogold electron microscopy of extracted ECM components from mouse growth plate showed that type XXVII collagen was a component of long non-banded fibrous structures, filamentous networks, and thin banded fibrils. The timing and location of synthesis suggest that type XXVII collagen plays a role during the calcification of cartilage and the transition of cartilage to bone. (C) 2007 Elsevier Inc. All rights reserved. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.bone.2007.06.024" target="_blank" rel="noreferrer noopener">10.1016/j.bone.2007.06.024</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2007 Bone Bruckner P Byers P H Cartilage chondrocyte col27a1 COL27Al endochondral Endocrinology & Metabolism expression Fernandes R J forms gene growth-plate Hansen U Hjorten R ix Jacquet R Journal Article or Conference Abstract Publication Krakow D Landis W J Pace J M Sebald E skeletogenesis Telfer H E type X-XVII collagen Underwood R A vertebrate fibrillar collagen Wachsmann-Hogiu S xi Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 646-655 Issue 6 Volume 18 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Testosterone Decreases 3 Beta-hydroxysteroid Dehydrogenase-isomerase Messenger Ribonucleic Acid In Cultured Mouse Leydig Cells By A Strain-specific Mechanism Publisher An entity responsible for making the resource available Journal of Andrology Date A point or period of time associated with an event in the lifecycle of the resource 1997 1997-11 Subject The topic of the resource 17-alpha-hydroxylase/c17-20 lyase; adult-rats; androgen; denovo synthesis; Endocrinology & Metabolism; expression; human chorionic-gonadotropin; inbred mice; luteinizing-hormone; receptor; rna; side-chain cleavage; steroidogenesis; testicular cells; testis Creator An entity primarily responsible for making the resource Heggland S J; Signs S A; Stalvey J R D Description An account of the resource We previously reported a strain-related difference in basal 3 beta-hydroxysteroid dehydrogenase-isomerase (3 beta HSD) activity in response to testosterone in cultured Leydig cells. The data suggested that the response to testosterone was androgen receptor mediated and that testosterone was acting via a irans-acting factor distal to the androgen receptor to regulate Leydig cell basal 3 beta HSD activity. This study was designed to determine whether the previous reported strain-related difference in basal 3 beta HSD activity in response to testosterone was due to a difference at the 3 beta HSD protein and/or at the mRNA level, In C57BL/6J Leydig cells, 2.0 mu M testosterone significantly decreased basal 3 beta HSD immunoreactive mass by day 6 in culture. Treatment with 2.0 mu M testosterone and 2.0 mu M hydroxyflutamide, an androgen receptor antagonist, negated the inhibitory effect of testosterone on C57BL/6J 3 beta HSD immunoreactive mass, Treatment with 2.0 mu M testosterone also significantly decreased 3 beta HSD mRNA content in C57BL/6J Leydig cells, which was detectable on day 3 in culture, In contrast to Leydig cells from C57BL/6J mice, Leydig cells from C3H/HeJ mice were not susceptible to the inhibitory effect of testosterone on 3 beta HSD. Treatment with 2.0 mu M testosterone had no detectable effect on C3H/HeJ 3 beta HSD immunoreactive mass or mRNA content at any time point in culture. These data indicate that the testosterone-induced loss of basal 3 beta HSD activity in C57BL/6J Leydig cells can he accounted for by the lass of 3 beta HSD immunoreactive mass, which is preceded by the loss of 3 beta HSD mRNA, and that the strain-related difference in the regulation of 3 beta HSD is present at all three levels. Thus, the putative trans-acting factor involved in the mechanism whereby testosterone decreases basal 3 beta HSD is likely to regulate the amount of 3 beta HSD mRNA. Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 17-alpha-hydroxylase/c17-20 lyase 1997 adult-rats androgen denovo synthesis Endocrinology & Metabolism expression Heggland S J human chorionic-gonadotropin inbred mice Journal Article or Conference Abstract Publication Journal of Andrology luteinizing-hormone Receptor RNA side-chain cleavage Signs S A Stalvey J R D steroidogenesis testicular cells testis Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S402-S402 Volume 25 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mcpip1 Is A Regulator Of Interleukin-6 Expression In Human Osteoarthritis Chondrocytes Publisher An entity responsible for making the resource available Osteoporosis International Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-04 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Haqqi T; Haseeb A; Makki M S Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2014 Endocrinology & Metabolism Haqqi T Haseeb A Journal Article or Conference Abstract Publication Makki M S Osteoporosis International Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S421-S421 Volume 25 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation Of Interleukin-6 Expression By A Ribonucleotidyl Transferase Zcchc6 In Human Chondrocytes Publisher An entity responsible for making the resource available Osteoporosis International Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-04 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Haqqi T; Arida A; Akhtar N Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2014 Akhtar N Arida A Endocrinology & Metabolism Haqqi T Journal Article or Conference Abstract Publication Osteoporosis International Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 441-441 Volume 88 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Low Level Suppression Of Hpa Axis From Ciclesonide Publisher An entity responsible for making the resource available Hormone Research in Paediatrics Date A point or period of time associated with an event in the lifecycle of the resource 2017 1905-07 Subject The topic of the resource Endocrinology & Metabolism; Pediatrics Creator An entity primarily responsible for making the resource Haidet J; Garibaldi L Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2017 Endocrinology & Metabolism Garibaldi L Haidet J Hormone Research in Paediatrics Journal Article or Conference Abstract Publication Pediatrics Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1186/1475-2840-11-150" target="_blank" rel="noreferrer noopener">http://doi.org/10.1186/1475-2840-11-150</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 11-11 Volume 11 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Detecting Dna Synthesis Of Neointimal Formation After Catheter Balloon Injury In Gk And In Wistar Rats: Using 5-ethynyl-2 '-deoxyuridine Publisher An entity responsible for making the resource available Cardiovascular Diabetology Date A point or period of time associated with an event in the lifecycle of the resource 2012 2012-12 Subject The topic of the resource alkynes; arterial injury; balloon injury; Cardiovascular System & Cardiology; carotid-artery; Catheter; cell-cycle progression; click chemistry; diabetes-mellitus; diabetes-mellitus; DNA synthesis; EdU; eluting stents; Endocrinology & Metabolism; in-vitro; mammalian target; Neointimal formation; PCNA; proliferation; terminal Creator An entity primarily responsible for making the resource Guo J S; Li D Y; Bai S R; Xu T D; Zhou Z M; Zhang Y B Description An account of the resource Background: Neointimal formation plays an important role in the pathogenesis of coronary restenosis after percutaneous coronary intervention (PCI), especially in patients with diabetes mellitus. Recently, some studies have shown that 5-ethynyl-2'-deoxyuridine (EdU) incorporation can serve as a novel alternative to the 5-bromo-2'-deoxyuridine (BrdU) antibody detection method for detection of DNA synthesis in regenerating avian cochlea, chick embryo and the adult nervous system. However, few studies have been performed to assess the suitability of EdU for detecting DNA synthesis in vascular neointima. Methods: The carotid artery balloon injury model was established in Goto-Kakizaki (GK) and Wistar rats. A Cell-Light (TM) EdU Kit was used to detect EdU-labeled cell nuclei of common carotid arteries at day 7 after catheter balloon injury. Different methods of injecting EdU were tested. The protein levels of proliferating cell nuclear antigen (PCNA) and p-Akt (Ser473), as well as the mRNA levels of PCNA were evaluated by Western blotting and quantitative real-time PCR (qRT-PCR), respectively. Immunohistochemical staining was also employed to visualize PCNA-positive cells. Results: At day 7 after catheter balloon injury, far more EdU-positive and PCNA-positive cells were observed in GK rats. When comparing groups that received different EdU doses, it was found that the percentage of EdU-positive cells at a dose of 100 mg/kg body weight was than at doses of 25 mg/kg and 50 mg/kg. The number of positive cells was significantly higher in the repeated injection group compared to the single injection group. Further, after balloon injury DNA synthesis in GK rats was more notable than in Wistar rats. Neointimal formation in GK rats was more obvious than in Wistar rats. The protein levels of PCNA and p-Akt (Ser473) and the mRNA levels of PCNA were increased in injured rats as compared to uninjured rats, and were significantly higher in GK rats than in Wistar rats. Conclusion: By intraperitoneal injections of EdU at a dose of 100 mg/kg three times, EdU incorporation can detect carotid arterial DNA synthesis caused by neointimal formation in GK rats and Wistar rats at day 7 after balloon injury by the EdU click reaction quickly and effectively. Moreover, more obvious DNA synthesis in the vascular neointima could be observed in GK rats than in Wistar rats. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1186/1475-2840-11-150" target="_blank" rel="noreferrer noopener">10.1186/1475-2840-11-150</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2012 alkynes arterial injury Bai S R balloon injury Cardiovascular Diabetology Cardiovascular System & Cardiology carotid-artery Catheter cell-cycle progression click chemistry diabetes-mellitus DNA synthesis EdU eluting stents Endocrinology & Metabolism Guo J S in-vitro Journal Article or Conference Abstract Publication Li D Y mammalian target Neointimal formation PCNA proliferation terminal Xu T D Zhang Y B Zhou Z M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/s8756-3282(01)00594-4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s8756-3282(01)00594-4</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 453-457 Issue 5 Volume 29 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Age- And Genotype-dependence Of Bone Material Properties In The Osteogenesis Imperfecta Murine Model (oim) Publisher An entity responsible for making the resource available Bone Date A point or period of time associated with an event in the lifecycle of the resource 2001 2001-11 Subject The topic of the resource (SAXS); calcified tissues; children; collagen; density; density distribution; electron-microscopy; Endocrinology & Metabolism; mechanical-properties; mice exhibit; microhardness; mineral; mineral crystals; murine model; osteogenesis imperfecta (OI); quantitative backscattered electron imaging (qBEI); small-angle X-ray scattering; tendon; x-ray-scattering Creator An entity primarily responsible for making the resource Grabner B; Landis W J; Roschger P; Rinnerthaler S; Peterlik H; Klaushofer K; Fratzl P Description An account of the resource Cortical mineralization of long bones was studied in collagen alpha2(I)-deficient mice (oim) used as a model for human osteogenesis imperfecta. Aspects of the age development of the mice were characterized by combining nanometer- to micrometer-scale structural analysis with microhardness measurements. Bone structure was determined from homozygous (oini/oim) and heterozygous (oim/+) mice and their normal (+/+) littermates as a function of animal age by small-angle X-ray scattering (SAXS) and quantitative backscattered electron imaging (qBEI) measurements. SAXS studies found anomalies in the size and arrangement of bone mineral crystals in both homozygous and heterozygous mice aged 1-14 months. Generally, the crystals were smaller in thickness and less well aligned in these mice compared with control animals. An increase in the mean crystal thickness of the bone was found within all three genotypes up to an age of 3 months. Vicker's hardness measurements were significantly enhanced for oim bone (homozygotes and heterozygotes) compared with controls. The microhardness values were correlated directly with increased mineral content of homozygous and heterozygous compared with control bone, as determined by qBEI analysis. There was also a significant increase of mineral content with age. Two possibilities for collagen-mineral association are discussed for explaining the increased hardness and mineral content of oim/oim bone, together with its decreased toughness and thinner mineral crystals. As a consequence of the present measurements, one model for oim bone could incorporate small and densely packed mineral crystals. A second model for possible collagen-mineral association in oim material would consist of two families of mineral crystals, one being smaller and the other being much larger than the crystals found in normal mouse long bones. (C) 2001 by Elsevier Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/s8756-3282(01)00594-4" target="_blank" rel="noreferrer noopener">10.1016/s8756-3282(01)00594-4</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication (SAXS) 2001 Bone calcified tissues Children Collagen density density distribution electron-microscopy Endocrinology & Metabolism Fratzl P Grabner B Journal Article or Conference Abstract Publication Klaushofer K Landis W J mechanical-properties mice exhibit microhardness mineral mineral crystals MURINE MODEL osteogenesis imperfecta (OI) Peterlik H quantitative backscattered electron imaging (qBEI) Rinnerthaler S Roschger P small-angle X-ray scattering tendon x-ray-scattering Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1210/en.2004-0728" target="_blank" rel="noreferrer noopener">http://doi.org/10.1210/en.2004-0728</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 5157-5167 Issue 11 Volume 145 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Differential Regulation Of The Cell Cycle By Alpha(1)-adrenergic Receptor Subtypes Publisher An entity responsible for making the resource available Endocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2004 2004-11 Subject The topic of the resource adventitial fibroblasts; alpha(1b)-adrenergic receptor; arterial blood-pressure; dna-synthesis; Endocrinology & Metabolism; fibroblasts; gene-expression; kinase pathways; mitogen-activated protein; proliferation; rat-1; smooth-muscle-cells Creator An entity primarily responsible for making the resource Gonzalez-Cabrera P J; Shi T; Yun J; McCune D F; Rorabaugh B R; Perez D M Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1210/en.2004-0728" target="_blank" rel="noreferrer noopener">10.1210/en.2004-0728</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2004 adventitial fibroblasts alpha(1b)-adrenergic receptor arterial blood-pressure dna-synthesis Endocrinology Endocrinology & Metabolism fibroblasts gene-expression Gonzalez-Cabrera P J kinase pathways McCune D F mitogen-activated protein Perez D M proliferation rat-1 Rorabaugh B R Shi T smooth-muscle-cells Yun J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S472-S472 Volume 15 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transgenic Mice Expressing Human Growth Hormone In Erythroid Cells Have Enhanced Bone Deposition Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2000 2000-09 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Flay N W; Vertel B M; Schneider G B; King D Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2000 Endocrinology & Metabolism Flay N W Journal of Bone and Mineral Research King D Schneider G B Vertel B M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages S372-S372 Volume 16 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Erythroid-specific Expression Of Human Growth Hormone In Marrow Stimulates Local Osteoblast Activity Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2001 2001-09 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Flay N W; Vertel B M; King D Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2001 Endocrinology & Metabolism Flay N W Journal of Bone and Mineral Research King D Vertel B M Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/0196-9781(84)90042-1" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0196-9781(84)90042-1</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 11-14 Issue 1 Volume 5 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cholecystokinin Receptor-binding Levels In The Genetically-obese Rat-brain Publisher An entity responsible for making the resource available Peptides Date A point or period of time associated with an event in the lifecycle of the resource 1984 1984 Subject The topic of the resource Biochemistry & Molecular Biology; Endocrinology & Metabolism; Pharmacology & Pharmacy Creator An entity primarily responsible for making the resource Finkelstein J A; Steggles A W; Martinez P; Praissman M Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/0196-9781(84)90042-1" target="_blank" rel="noreferrer noopener">10.1016/0196-9781(84)90042-1</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1984 Biochemistry & Molecular Biology Endocrinology & Metabolism Finkelstein J A Martinez P Peptides Pharmacology & Pharmacy Praissman M Steggles A W Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/s0196-9781(81)80006-x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0196-9781(81)80006-x</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 19-21 Issue 1 Volume 2 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Levels Of Gastrin-cholecystokinin-like Immunoreactivity In The Brains Of Genetically-obese And Non-obese Rats Publisher An entity responsible for making the resource available Peptides Date A point or period of time associated with an event in the lifecycle of the resource 1981 1981 Subject The topic of the resource Biochemistry & Molecular Biology; Endocrinology & Metabolism; Pharmacology & Pharmacy Creator An entity primarily responsible for making the resource Finkelstein J A; Steggles A W; Lotstra F; Vanderhaeghen J J Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/s0196-9781(81)80006-x" target="_blank" rel="noreferrer noopener">10.1016/s0196-9781(81)80006-x</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1981 Biochemistry & Molecular Biology Endocrinology & Metabolism Finkelstein J A Lotstra F Peptides Pharmacology & Pharmacy Steggles A W Vanderhaeghen J J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 2-2 Issue 3 Volume 35 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Autoimmune Polyglandular Syndrome Ii In A Patient With Takotsubo's Cardiomyopathy Publisher An entity responsible for making the resource available Endocrine Reviews Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-06 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Detoya K C B; Ciltea D; Timberlake D; Haller N A Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2014 Ciltea D Detoya K C B Endocrine reviews Endocrinology & Metabolism Haller N A Timberlake D Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 2-2 Issue 3 Volume 35 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Adrenal Cortical Adenoma Transforming Into Adrenocortical Carcinoma In A Patient Without Cushing's Features Publisher An entity responsible for making the resource available Endocrine Reviews Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-06 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Detoya K C B; Ciltea D; Rehman A; Haller N A Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2014 Ciltea D Detoya K C B Endocrine reviews Endocrinology & Metabolism Haller N A Rehman A Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.psyneunen.2004.06.004" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.psyneunen.2004.06.004</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 121-128 Issue 2 Volume 30 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Initial Urinary Epinephrine And Cortisol Levels Predict Acute Ptsd Symptoms In Child Trauma Victims Publisher An entity responsible for making the resource available Psychoneuroendocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2005 2005-02 Subject The topic of the resource catecholamine; catecholamines; children; combat veterans; cortisol; dexamethasone-suppression; Endocrinology & Metabolism; excretion; Neurosciences & Neurology; pituitary; posttraumatic-stress-disorder; psychiatric diagnoses; Psychiatry; PTSD; severity; survivors; trauma; women Creator An entity primarily responsible for making the resource Delahanty D L; Nugent N R; Christopher N C; Walsh M Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.psyneunen.2004.06.004" target="_blank" rel="noreferrer noopener">10.1016/j.psyneunen.2004.06.004</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2005 catecholamine catecholamines Children Christopher N C combat veterans Cortisol Delahanty D L dexamethasone-suppression Endocrinology & Metabolism excretion Neurosciences & Neurology Nugent N R pituitary posttraumatic-stress-disorder psychiatric diagnoses Psychiatry Psychoneuroendocrinology PTSD severity Survivors trauma Walsh M Women Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1159/000079664" target="_blank" rel="noreferrer noopener">http://doi.org/10.1159/000079664</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 296-304 Issue 6 Volume 79 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Dopamine Transporter As A Marker Of Neuroprotection In Methamphetamine-lesioned Mice Treated Acutely With Estradiol Publisher An entity responsible for making the resource available Neuroendocrinology Date A point or period of time associated with an event in the lifecycle of the resource 2004 1905-06 Subject The topic of the resource 17-beta-estradiol; brain; depletion; dopamine transporter; Endocrinology & Metabolism; estrogen; gender-differences; gonadal steroids; induced neurotoxicity; methamphetamine; neuroprotection; Neurosciences & Neurology; parkinsons-disease; progesterone; rat; striatal dopamine; striatum; substantia nigra; system Creator An entity primarily responsible for making the resource D'Astous M; Gajjar T M; Dluzen D E; Di Paolo T Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1159/000079664" target="_blank" rel="noreferrer noopener">10.1159/000079664</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 17-beta-estradiol 2004 Brain D'Astous M depletion Di Paolo T Dluzen D E Dopamine transporter Endocrinology & Metabolism estrogen Gajjar T M gender-differences gonadal steroids induced neurotoxicity Methamphetamine Neuroendocrinology Neuroprotection Neurosciences & Neurology parkinsons-disease progesterone rat striatal dopamine striatum SUBSTANTIA nigra system Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 368-368 Volume 33 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Therapeutic Effect Of Gpnmb In A Traumatically-induced Osteoarthritic Model Publisher An entity responsible for making the resource available Journal of Bone and Mineral Research Date A point or period of time associated with an event in the lifecycle of the resource 2018 2018-11 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Cook B; Aladlaan A; Desanto M; Safadi F F Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 2018 Aladlaan A Cook B Desanto M Endocrinology & Metabolism Journal of Bone and Mineral Research Safadi F F Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/0196-9781(84)90054-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0196-9781(84)90054-8</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 73-80 Issue 1 Volume 5 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource INVITRO, RELEASE OF CHOLECYSTOKININ FROM HYPOTHALAMUS AND FRONTAL-CORTEX OF SPRAGUE-DAWLEY, ZUCKER LEAN (FA/-) AND OBESE (FA/FA) RATS Publisher An entity responsible for making the resource available Peptides Date A point or period of time associated with an event in the lifecycle of the resource 1984 1984 Subject The topic of the resource Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Micevych P E; Go V L W; Yaksh T L; Finkelstein J Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/0196-9781(84)90054-8" target="_blank" rel="noreferrer noopener">10.1016/0196-9781(84)90054-8</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1984 Biochemistry & Molecular Biology Endocrinology & Metabolism Finkelstein J Go V L W Journal Article or Conference Abstract Publication Micevych P E Peptides Pharmacology & Pharmacy Yaksh T L Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1210/jcem-52-2-247" target="_blank" rel="noreferrer noopener">http://doi.org/10.1210/jcem-52-2-247</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 247-251 Issue 2 Volume 52 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource THYROID HEMIAGENESIS (HOCKEY STICK SIGN) - A REVIEW OF THE WORLD LITERATURE AND A REPORT OF 4 CASES Publisher An entity responsible for making the resource available Journal of Clinical Endocrinology & Metabolism Date A point or period of time associated with an event in the lifecycle of the resource 1981 1981 Subject The topic of the resource Endocrinology & Metabolism Creator An entity primarily responsible for making the resource Melnick J C; Stemkowski P E Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1210/jcem-52-2-247" target="_blank" rel="noreferrer noopener">10.1210/jcem-52-2-247</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1981 Endocrinology & Metabolism Journal Article or Conference Abstract Publication Journal of Clinical Endocrinology & Metabolism Melnick J C Stemkowski P E Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1006/hbeh.1994.1002" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/hbeh.1994.1002</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 16-28 Issue 1 Volume 28 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource EFFECTS OF ESTROGEN-TREATMENT ON SENSORIMOTOR TASK-PERFORMANCE AND BRAIN DOPAMINE CONCENTRATIONS IN GONADECTOMIZED MALE AND FEMALE CD-1 MICE Publisher An entity responsible for making the resource available Hormones and Behavior Date A point or period of time associated with an event in the lifecycle of the resource 1994 1994-03 Subject The topic of the resource Endocrinology & Metabolism; parkinsons-disease; Behavioral Sciences; Sensitivity; striatum; amphetamine; sex-differences; estradiol; release; locomotor-activity; castrated male-rats; rotational behavior Creator An entity primarily responsible for making the resource McDermott J L; Kreutzberg J D; Liu B J; Dluzen D E Description An account of the resource In Experiment I, castrated male and female CD-1 mice +/- estradiol benzoate (EB) treatment were tested for their performance on a skilled sensorimotor task consisting of walking across beams of varying widths (6, 9, 12, and 21 mm). To evaluate whether behavioral performance was related to nigrostriatal dopaminergic function, tissue dopamine concentrations were determined from the corpus striatum as well as the hypothalamus and olfactory tubercle. In general, sensorimotor performance improved for all treatment conditions as the beam width increased. Castrated male mice treated with oil vehicle showed the worst performance as indicated by significantly greater amounts of time to cross the beam. Treatment of castrated males with EB significantly improved their performance. Performance of the castrated females was not changed by EB treatment and was similar to that observed with the castrated + EB males. Significant gender differences in dopamine concentrations (female > male) were obtained in the corpus striatum, as well as the olfactory tubercle and hypothalamus. Dopamine levels were unaltered by EB treatment. In Experiment II, behavioral and neurochemical determinations were directly compared between castrated and intact male mice. Behavioral performance of castrates was significantly reduced compared to intact males. No differences in dopamine concentrations were obtained between these two groups; however, the hypothalamic dopamine/DOPAC ratio of castrates was significantly greater than that of intact male mice. These results demonstrate significant modulatory effects of EB in castrated male, but not female, mice upon sensorimotor performance and indicate that this task may provide an effective means to partial out modulatory effects of gonadal steroid hormones upon skilled sensorimotor performance. When the data of Experiments I and II are combined, it appears that the basis of this sensorimotor deficit in the males is the absence of gonadal steroid hormones. In addition, these results reveal significant gender differences in various dopaminergic systems in these mice. (C) 1994 Academic Press, Inc. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1006/hbeh.1994.1002" target="_blank" rel="noreferrer noopener">10.1006/hbeh.1994.1002</a> Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1994 amphetamine Behavioral Sciences castrated male-rats Dluzen D E Endocrinology & Metabolism estradiol Hormones and Behavior Journal Article or Conference Abstract Publication Kreutzberg J D Liu B J locomotor-activity McDermott J L parkinsons-disease release rotational behavior sensitivity sex-differences striatum Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address n/a Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 801-803 Issue 10 Volume 11 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Interactive effects of tamoxifen and oestrogen upon the nigrostriatal dopaminergic system: Long-term treatments Publisher An entity responsible for making the resource available Journal of Neuroendocrinology Date A point or period of time associated with an event in the lifecycle of the resource 1999 1999-10 Subject The topic of the resource receptors; Neurosciences & Neurology; Endocrinology & Metabolism; estrogen; binding; catecholamines; brain; striatum; time; amphetamine; estradiol; antiestrogens; ovarian steroids; sexual-behavior; anti-oestrogens Creator An entity primarily responsible for making the resource McDermott J L; Anderson L I; Dluzen D E Description An account of the resource In the present report adult female rats were ovariectomized (OVX) and assigned to one of four treatment conditions. Treatments consisted of administering pellets containing 17 beta-oestradiol (E), tamoxifen (TMX), a combination of TMX and E or no further treatment (OVX), Animals received these treatments immediately following OVX and were maintained in these conditions for a 40-day period. Subsequently, the corpus striatum (CS) was dissected from each animal and prepared for determinations of basal and amphetamine stimulated DA output using in-vitro superfusion. No statistically significant differences among the four treatment groups were obtained for basal dopamine output. The highest levels of amphetamine-stimulated dopamine responses were obtained from E treated rats. These values were significantly greater than that obtained from OVX rats and rats treated with a combination of TMX + E. The significance of these findings is that they indicate both a non-traditional central nervous system site and mechanism of action through which tamoxifen-oestrogen interactions can function. Such data may have important implications for administration of tamoxifen to premenopausal women as this anti-oestrogen may compromise nigrostriatal dopaminergic function under conditions where oestrogenic modulation is present. Identifier An unambiguous reference to the resource within a given context n/a Format The file format, physical medium, or dimensions of the resource Journal Article or Conference Abstract Publication 1999 amphetamine Anderson L I anti-oestrogens antiestrogens Binding Brain catecholamines Dluzen D E Endocrinology & Metabolism estradiol estrogen Journal Article or Conference Abstract Publication Journal of neuroendocrinology McDermott J L Neurosciences & Neurology ovarian steroids Receptors sexual-behavior striatum Time