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<a href="http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ajo.2020.06.040</a>
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Pages
215-221
Volume
219
ISSN
0002-9394
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1016/j.ajo.2020.06.040</a>
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October 2020 List
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Title
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The short-term effect of a single lapse in anti–vascular endothelial growth factor treatment for diabetic macular edema within routine clinical practice
Publisher
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American Journal of Ophthalmology
Date
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2020
2020-11-01
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Yalamanchili SP;Maatouk CM;Enwere DU;Conti TF;Hom GL;Briskin IN;Greenlee TE;Babiuch AS;Singh RP
Description
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Purpose Diabetic macular edema (DME) is a leading cause of vision loss in diabetics. Anti–vascular endothelial growth factor (VEGF) therapy has been shown to be an effective treatment option for DME, although the injections are costly and require frequent visits, which increases the risk for unintended treatment lapses. The aim of this study is to characterize the effects of an unintended treatment lapse in patients with DME undergoing anti-VEGF therapy.
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<a href="http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">10.1016/j.ajo.2020.06.040</a>
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2020
American Journal of Ophthalmology
Babiuch AS
Briskin IN
Conti TF
Enwere DU
Greenlee TE
Hom GL
journalArticle
Maatouk CM
NEOMED College of Medicine Student
NEOMED Student Publications
October 2020 List
Singh RP
Yalamanchili SP
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ajo.2020.06.040</a>
ISSN
1879-1891 0002-9394 0002-9394
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1016/j.ajo.2020.06.040</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
August 2020 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The short-term effect of a single lapse in anti-vascular endothelial growth factor treatment for diabetic macular edemawithin routine clinical practice.
Publisher
An entity responsible for making the resource available
American Journal of Ophthalmology
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-07-05
Creator
An entity primarily responsible for making the resource
Yalamanchili SP; Maatouk CM; Enwere DU; Conti TF; Hom GL; Briskin IN; Greenlee TE; Babiuch AS; Singh RP
Description
An account of the resource
PURPOSE: Diabetic macular edema (DME) is a leading cause of vision loss in diabetics. Anti-vascular endothelial growth factor (VEGF) therapy has been shown to be an effective treatment option for DME, although the injections are costly and require frequent visits which increases the risk for unintended treatment lapses. The aim of this study is to characterize the effects of an unintended treatment lapse in patients with DME undergoing anti-VEGF therapy. DESIGN: Retrospective, comparative case series. METHODS: This retrospective chart review compared patients seen in a multicenter institutional practice with DME exhibiting an un-intended minimum three-month lapse in anti-VEGF treatment, with a control group of DME patients receiving regular anti-VEGF treatment without lapses. The primary outcome was difference in central subfield thickness (CST) between the control group and the treatment lapse group at 6 months following treatment lapse. RESULTS: A total of 164 patients were evaluated, 82 patients in the treatment lapse group and 82 patients in the control group. The average age was 65 years, and the average lapse in treatment was 6.2 ± 3.5 months (range 3-24 months). Comparison of data between the lapse and control groups revealed no significant differences in CST respectively [(359.9±108.3 μm), (335.4±94.6 μM)], p=0.066 or in visual acuity (VA) respectively [(66.5±14.3), (68.9±14.5)], p=0.136. Limitations included a relatively small sample size, retrospective nature, and only a single lapse being evaluated. CONCLUSIONS: An un-intended, single, relatively short-term lapse in anti-VEGF treatment in patients with DME did not appear to result in significant anatomic or visual compromise upon resumption of regular follow-up and treatment.
Identifier
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<a href="http://doi.org/10.1016/j.ajo.2020.06.040" target="_blank" rel="noreferrer noopener">10.1016/j.ajo.2020.06.040</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
American Journal of Ophthalmology
August 2020 List
Babiuch AS
Briskin IN
Conti TF
Enwere DU
Greenlee TE
Hom GL
journalArticle
Maatouk CM
NEOMED College of Medicine Student
NEOMED Student Publications
Singh RP
Yalamanchili SP