1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0040-8166(92)90022-y" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0040-8166(92)90022-y</a>
Pages
869–878
Issue
6
Volume
24
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Female sex steroid induced epithelial changes in the gallbladder of the ovariectomized Syrian hamster.
Publisher
An entity responsible for making the resource available
Tissue & cell
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1905-06
Subject
The topic of the resource
Animals; Cholesterol; Cricetinae; Dietary/*administration & dosage; Electron; Epithelium/drug effects/ultrastructure; Estrogens/*adverse effects; Female; Gallbladder/*drug effects/ultrastructure; Mesocricetus; Microscopy; Ovariectomy; Ovary/*physiology; Progesterone/*adverse effects; Scanning
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Karkare S; Ko W; Kelly T R
Description
An account of the resource
Ovariectomized Syrian hamsters treated by female sex steroids during a 1-month period show gallbladder surface epithelial changes in the fundic area consistent with apical bulging and decapitations of the epithelial cells. These events were detected in the infundibulum and the fundic or body regions of estrogen- and estrogen+progesterone-treated hamsters. In control hamsters, these events were restricted to the region in the vicinity of the bile duct. Following steroid treatment, intraluminal deposits detected resembled Ca-bilirubinate deposits described in previous studies while decapitations are similar to endometrial epithelium changes associated with hormonal physiological changes or treatments. Moreover some small electron-dense deposits are comparable to those found in human cholesterol gallstones. This report indicates that, besides an alteration in bile composition, cell fragments originating from the surface epithelium of the bile duct and/or of the gallbladder mucosal epithelium could participate in gallstone nucleation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0040-8166(92)90022-y" target="_blank" rel="noreferrer noopener">10.1016/0040-8166(92)90022-y</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Animals
Cholesterol
Cricetinae
Dietary/*administration & dosage
Electron
Epithelium/drug effects/ultrastructure
Estrogens/*adverse effects
Female
Gallbladder/*drug effects/ultrastructure
Gilloteaux J
Karkare S
Kelly T R
Ko W
Mesocricetus
Microscopy
Ovariectomy
Ovary/*physiology
Progesterone/*adverse effects
Scanning
Tissue & cell