1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
71–74
Issue
2
Volume
319
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Estrogen receptor-alpha and -beta coexist in a subpopulation of sensory neurons of female rat dorsal root ganglia.
Publisher
An entity responsible for making the resource available
Neuroscience letters
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
2002-02
Subject
The topic of the resource
Female; Animals; Rats; Cell Count; *Sex Characteristics; Fluorescent Antibody Technique; Estrous Cycle/*physiology; Estrogen Receptor alpha; Cell Nucleus/metabolism/ultrastructure; Estrogen Receptor beta; Estrogens/*metabolism; Ganglia; Neurons; Sprague-Dawley; Receptors; Spinal/cytology/*metabolism; Genitalia; Estrogen/*metabolism; Afferent/cytology/*metabolism; Female/innervation
Creator
An entity primarily responsible for making the resource
Papka Raymond E; Storey-Workley Megan
Description
An account of the resource
Immunoreactivities for estrogen receptor-alpha (ER-alpha) and ER-beta are expressed in sensory neurons of the dorsal root ganglia (DRG). It has not been established, however, if the two receptor subtypes coexist in the same neuron. Double-staining immunohistochemical techniques were used to determine if subpopulations of neurons in the lumbosacral DRG exist based on their content of ERs. Results indicate that some neurons (approximately 17%) of the L6-S1 DRG contain ER-alpha -, some (approximately 23%) contain ER-beta - immunoreactivity and some (approximately 5%) express immunoreactivity for both subtypes of the ER. These results suggest that many sensory neurons can respond to estrogens, but estrogens may produce different morphofunctional effects in different neurons based on their expression of ER subtypes.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Sex Characteristics
2002
Afferent/cytology/*metabolism
Animals
Cell Count
Cell Nucleus/metabolism/ultrastructure
Estrogen Receptor alpha
Estrogen Receptor beta
Estrogen/*metabolism
Estrogens/*metabolism
Estrous Cycle/*physiology
Female
Female/innervation
Fluorescent Antibody Technique
Ganglia
Genitalia
Neurons
Neuroscience letters
Papka Raymond E
Rats
Receptors
Spinal/cytology/*metabolism
Sprague-Dawley
Storey-Workley Megan
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.neulet.2003.09.081" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.neulet.2003.09.081</a>
Pages
239–241
Issue
3
Volume
354
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat.
Publisher
An entity responsible for making the resource available
Neuroscience letters
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-01
Subject
The topic of the resource
*Sex Characteristics; Animal; Animals; Behavior; Carrageenan; Castration/methods; Estrous Cycle/*physiology; Female; Gonadal Steroid Hormones/*physiology; Inbred F344; Male; Pain Measurement/methods; Pain Threshold; Pain/chemically induced/*physiopathology; Physical Stimulation; Rats; Reaction Time
Creator
An entity primarily responsible for making the resource
Tall Jill M; Crisp Terriann
Description
An account of the resource
The effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat were investigated. A plantar analgesic meter was used to measure carrageenan-induced changes in paw withdrawal latency (PWL) values, and von Frey monofilaments were used to assess changes in paw withdrawal threshold (PWT) values in response to tactile-evoked (mechanical) stimuli. The data revealed that PWL values were significantly greater in gonadally-intact females than in gonadally-intact males, and this response was abolished by surgical gonadectomies. Gonadally-intact as well as gonadectomized male and female rats also exhibited significant carrageenan-induced decreases in PWT, but neither sex- nor gonadectomy-related differences were detected in the development of mechanical allodynia. These findings demonstrate that intraplantar carrageenan induces nociceptive behaviors in rats that are differentially affected by sex and gonadal hormones.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.neulet.2003.09.081" target="_blank" rel="noreferrer noopener">10.1016/j.neulet.2003.09.081</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Sex Characteristics
2004
Animal
Animals
Behavior
Carrageenan
Castration/methods
Crisp Terriann
Estrous Cycle/*physiology
Female
Gonadal Steroid Hormones/*physiology
Inbred F344
Male
Neuroscience letters
Pain Measurement/methods
Pain Threshold
Pain/chemically induced/*physiopathology
Physical Stimulation
Rats
Reaction Time
Tall Jill M