Induction of NMDA receptor-independent long-term potentiation (LTP) in visual cortex of adult rats.
Animals; Electric Stimulation; Evoked Potentials/physiology; In Vitro Techniques; N-Methyl-D-Aspartate/antagonists & inhibitors/drug effects/*physiology; Neuronal Plasticity/drug effects/*physiology; Rats; Receptors; Synapses/physiology; Visual Cortex/*physiology
The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in its induction. The field potential elicited in layer III in response to stimulation of the subcortical white matter consisted of a component with peak latency 5-8 ms (N1) and, in most slices, a second component with peak latency
Aroniadou V A; Teyler T J
Brain research
1992
1992-07
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1016/0006-8993(92)90891-c" target="_blank" rel="noreferrer noopener">10.1016/0006-8993(92)90891-c</a>
Presynaptic mechanism for heterosynaptic, posttetanic depression in area CA1 of rat hippocampus.
Afferent/drug effects; Animals; Electric Stimulation; Electrophysiology; Evoked Potentials/physiology; Glutamate/drug effects; Glutamates/pharmacology; Glutamic Acid; Hippocampus/drug effects/*physiology; In Vitro Techniques; Membrane Potentials/physiology; N-Methyl-D-Aspartate/antagonists & inhibitors; Neuronal Plasticity/drug effects/physiology; Neurons; Presynaptic/drug effects/*physiology; Pyramidal Cells/drug effects; Rats; Receptors; Synapses/drug effects/*physiology
Conditioning stimulation applied to afferent fibers in stratum radiatum or stratum oriens of hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of excitatory postsynaptic potentials (EPSPs). PTD amounted to a
Grover L M; Teyler T J
Synapse (New York, N.Y.)
1993
1993-10
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1002/syn.890150207" target="_blank" rel="noreferrer noopener">10.1002/syn.890150207</a>