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Text
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URL Address
<a href="http://doi.org/10.1111/cup.13903" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/cup.13903</a>
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ISSN
1600-0560 0303-6987
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Update Year & Number
October 2020 List
NEOMED College
NEOMED College of Medicine Student
NEOMED Department
NEOMED Student Publications
Dublin Core
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Title
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Spitz nevi in african americans: A retrospective chart review of 11 patients.
Publisher
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Journal of Cutaneous Pathology
Date
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2020
2020-10-16
Subject
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African Americans; nevi; nevus; Spitz; Spitzoid
Creator
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Farid YI;Honda KS
Description
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BACKGROUND: Spitz nevi are benign melanocytic neoplasms that typically present as rapidly growing solitary lesions on the head, neck, or lower extremities. Very rare reports have been described in African Americans. METHODS: A single-institution 29-year retrospective review of African American patients diagnosed with Spitz nevi was thoroughly analyzed in order to characterize these rare clinical and histopathologic presentations. RESULTS: Eleven African Americans with spitzoid lesions were identified. Seven (64%) cases were in pediatric patients and nine (82%) were in females. Most lesions were hyperpigmented (73%) and elevated (82%). Six (55%) were compound Spitz nevi, three (27%) were dermal Spitz nevi, and two (18%) were junctional Spitz nevi. Two lesions had more than one atypical feature. Histopathologically, common features were symmetry, sharp circumscription, pagetoid spread (55%) with most being centrally, predominance of epithelioid cells (64%), Kamino bodies (45%), slight pigmentation (46%), maturation of dermal component with depth, and lack of subcutaneous fat involvement or ulceration. Excision was performed on all patients and there were no recurrences although follow-up was limited. CONCLUSION: Awareness of the possibility and various presentations of Spitz nevi in African Americans will help prevent misdiagnosis.
Identifier
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<a href="http://doi.org/10.1111/cup.13903" target="_blank" rel="noreferrer noopener">10.1111/cup.13903</a>
Format
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journalArticle
2020
African Americans
Farid YI
Honda KS
Journal of cutaneous pathology
journalArticle
NEOMED College of Medicine Student
NEOMED Student Publications
nevi
Nevus
October 2020 List
Spitz
Spitzoid