Safety of Trimethoprim-Sulfamethoxazole for Pneumocystis Jirovecii Pneumonia Prophylaxis in Patients Taking Methotrexate.
Autoimmune disease; Chronic inflammatory disease; Methotrexate; Pneumocystis Jirovecii Pneumonia; Trimethoprim-Sulfamethoxazole
Havele Sonia A; Ellis Ariana; Chaitoff Alex; Khanna Urmi; Parambil Joseph; Langford Carol A; Fernandez Anthony P
Journal of the American Academy of Dermatology
2020
2020-04-19
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.1016/j.jaad.2020.04.040" target="_blank" rel="noreferrer noopener">10.1016/j.jaad.2020.04.040</a>
Reply to: "Evidence-based guidelines for tuberculosis screening before biologic treatment initiation".
Fernandez Anthony P; Ellis Ariana; Khanna Urmi; Galadari AbdulAziz
Journal of the American Academy of Dermatology
2020
2020-03-25
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.1016/j.jaad.2020.03.039" target="_blank" rel="noreferrer noopener">10.1016/j.jaad.2020.03.039</a>
Diagnoses of hospitalized patients with skin abnormalities prompting biopsy by consulting dermatologists: A 3-year review from a tertiary care center
dermatology hospital consultation; dermatopathology; inpatient dermatology; skin biopsy
BACKGROUND: Dermatologists play an important role in diagnosing and managing hospitalized patients with cutaneous abnormalities. Skin biopsies remain an indispensable tool for aiding dermatologists in accurate diagnosis and treatment. We aimed to determine the range of conditions, and the most common conditions, prompting skin biopsy by dermatology hospital consultation (HCON) services to aid in evaluation of hospitalized patients. METHODS: All hospitalized patients seen by a single tertiary care center dermatology HCON service between 2015 and 2018 who had associated skin biopsies were identified. Histologic features and clinical diagnoses of each patient were classified into 13 histologic reaction pattern categories. RESULTS: Eight hundred and thirty one inpatients evaluated by our dermatology HCON service had 914 skin biopsies. The most frequent diagnostic categories prompting biopsy were vasculopathic (17.6%), interface dermatitis (16.5%), infectious (12.6%), and spongiotic dermatitis (10.9%). The most frequent diagnostic categories included drug reaction (13.2%), leukocytoclastic vasculitis (8.5%), skin cancer (5.4%), graft-vs-host disease (3.5%), connective tissue disease (3.3%), and calciphylaxis (3.0%). CONCLUSION: Our study suggests a variety of serious diseases affecting inpatients prompts biopsy by dermatology consultation services. Educational curricula for dermatology and pathology residents, fellows, and staff designed with these data may enhance knowledge that improves the quality of inpatient dermatology care.
Ellis Ariana; Billings Steven D; Khanna Urmi; Warren Christine B; Piliang Melissa; Vij Alok; Ko Jennifer S; Bergfeld Wilma F; Fernandez Anthony P
Journal of Cutaneous Pathology
2019
2019-12-17
Journal Article
<a href="http://doi.org/10.1111/cup.13628" target="_blank" rel="noreferrer noopener">10.1111/cup.13628</a>
PMID: 31845375
Adverse Cutaneous Reactions of Common Biologic Medications for Rheumatic Diseases
Adverse cutaneous effects; Biologics; Infusion reaction; Rheumatic diseases
Purpose of Review: Within the last two decades, the application of biologic medications for rheumatic diseases has greatly expanded. Therefore, it is important for clinicians to be knowledgeable about potential adverse reactions of this medication class. The goal of this review is to discuss the current understanding of cutaneous adverse reactions that may occur with common biologic medications utilized in the management of rheumatic diseases.Recent Findings: A variety of cutaneous reactions have been reported in association with biologics commonly used to treat rheumatic diseases. Here, we review cutaneous reactions reported with tumor necrosis factor-α inhibitors, abatacept (co-stimulation blockade), CD20 inhibitors, IL-17 inhibitors, IL-12/23 inhibitors, and IL-6 inhibitors. The side effects, in most cases, can be managed without discontinuation of the associated biologic medication. However, there are identified reactions that warrant discontinuation or adjustments in order to prevent additional and possibly permanent patient morbidity.Summary: While causation is often difficult to prove when cutaneous side effects are observed in relation to biologic therapies, it is important for clinicians to be aware of characteristic or distinguishing cutaneous reactions in order to treat patients with rheumatic diseases safely and effectively.
Khanna Urmi; Ellis Ariana M; Fernandez Anthony P
Current Treatment Options in Rheumatology
2019
1905-07
Journal Article
<a href="http://doi.org/10.1007/s40674-019-00129-7" target="_blank" rel="noreferrer noopener">10.1007/s40674-019-00129-7</a>
A Refractory Blistering Eruption in a Young Woman With a Positive Antinuclear Antibody
Khanna Urmi; Ellis Ariana; Galadari AbdulAziz; Fernandez Anthony P
Journal Of Clinical Rheumatology: Practical Reports On Rheumatic & Musculoskeletal Diseases
2019
2019-10-11
Journal Article
<a href="http://doi.org/10.1097/RHU.0000000000001188" target="_blank" rel="noreferrer noopener">10.1097/RHU.0000000000001188</a>
PMID: 31609816
Disseminated discoid lupus erythematosus mimicking Degos disease
Khanna Urmi; Semsarzadeh Nina; La Senna Charlotte; Ellis Ariana; Galadari AbdulAziz; Fernandez Anthony P
The Australasian Journal of Dermatology
2019
2019-08
<a href="http://doi.org/10.1111/ajd.13139" target="_blank" rel="noreferrer noopener">10.1111/ajd.13139</a>
Parvovirus mimicking acute HIV infection.
Adult; Humans; Male; HIV Infections/*diagnosis; Parvoviridae Infections/*diagnosis; Diagnosis; Differential
Saed Stephanie; Weinstein Velez Mara; Tomecki Kenneth J; Fernandez Anthony P
Cleveland Clinic journal of medicine
2015
2015-08
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.3949/ccjm.82a.14141" target="_blank" rel="noreferrer noopener">10.3949/ccjm.82a.14141</a>