2
40
42
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2146/ajhp130118" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/ajhp130118</a>
Pages
1908–1912
Issue
21
Volume
70
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Evaluation and use of a rapid Staphylococcus aureus assay by an antimicrobial stewardship program.
Publisher
An entity responsible for making the resource available
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-11
Subject
The topic of the resource
Humans; Time Factors; Microbial Sensitivity Tests; Sensitivity and Specificity; Prospective Studies; Hospitals; Anti-Bacterial Agents/administration & dosage/*pharmacology; Bacteriological Techniques; False Negative Reactions; Methicillin-Resistant Staphylococcus aureus/*isolation & purification; Staphylococcal Infections/*diagnosis/microbiology; Staphylococcus aureus/*isolation & purification; Cell Culture Techniques; Chromatography; Human; Funding Source; Community; Affinity; Observational Methods; Biological Assay – Methods; Methicillin-Resistant Staphylococcus Aureus – Analysis
Creator
An entity primarily responsible for making the resource
Trienski Tamara L; Barrett Heather L; Pasquale Timothy R; DiPersio Joseph R; File Thomas M Jr
Description
An account of the resource
PURPOSE: The performance of a rapid test for methicillin-resistant Staphylococcus aureus (MRSA) in a large community hospital was investigated. METHODS: A prospective observational study was conducted to evaluate an immunochromatographic assay (Alere PBP2a Culture Colony Test, Alere Scarborough, Inc.) for rapid differentiation of MRSA and methicillin-susceptible S. aureus (MSSA) strains using isolates cultured overnight on common laboratory media. S. aureus isolates cultured for 12-24 hours were tested with the assay, which detects penicillin-binding protein 2a (PBP2a) and provides results in six minutes. The test results were compared with data from standard overnight antimicrobial susceptibility testing to determine the assay's sensitivity and specificity. Changes in therapy associated with use of the rapid assay were evaluated. RESULTS: Over an 11-month period, 661 inpatient isolates from mostly nonhematologic sites were tested. There were six false-negative results, indicating assay sensitivity of 98.4%, with no false positives (specificity of 100%). Eight invalid test results were documented. During designated evaluation periods, a total of 169 patient cases involving PBP2a testing were reviewed by the hospital's antimicrobial stewardship pharmacist. In 63 of those cases (37%), changes in therapy were implemented on the day of test result posting. Interventions often involved switching patients from inappropriate to appropriate MRSA therapy or optimizing MRSA- or MSSA-targeted therapy. CONCLUSION: An assay for quickly differentiating between MRSA and MSSA was highly sensitive, highly specific, and inexpensive in actual hospital use and led to rapid prescription of appropriate antistaphylococcal therapy 24-48 hours after culture specimens were collected.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.2146/ajhp130118" target="_blank" rel="noreferrer noopener">10.2146/ajhp130118</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2013
Affinity
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Anti-Bacterial Agents/administration & dosage/*pharmacology
Bacteriological Techniques
Barrett Heather L
Biological Assay – Methods
Cell Culture Techniques
Chromatography
Community
Department of Internal Medicine
DiPersio Joseph R
False Negative Reactions
File Thomas M Jr
Funding Source
Hospitals
Human
Humans
Methicillin-Resistant Staphylococcus Aureus – Analysis
Methicillin-Resistant Staphylococcus aureus/*isolation & purification
Microbial Sensitivity Tests
NEOMED College of Medicine
Observational Methods
Pasquale Timothy R
Prospective Studies
Sensitivity and Specificity
Staphylococcal Infections/*diagnosis/microbiology
Staphylococcus aureus/*isolation & purification
Time Factors
Trienski Tamara L
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/cid/ciy866" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/cid/ciy866</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza.
Publisher
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-12
Creator
An entity primarily responsible for making the resource
Uyeki Timothy M; Bernstein Henry H; Bradley John S; Englund Janet A; File Thomas M Jr; Fry Alicia M; Gravenstein Stefan; Hayden Frederick G; Harper Scott A; Hirshon Jon Mark; Ison Michael G; Johnston B Lynn; Knight Shandra L; McGeer Allison; Riley Laura E; Wolfe Cameron R; Alexander Paul E; Pavia Andrew T
Description
An account of the resource
These clinical practice guidelines are an update of the guidelines published by the Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza pandemic. This document addresses new information regarding diagnostic testing, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal influenza. It is intended for use by primary care clinicians, obstetricians, emergency medicine providers, hospitalists, laboratorians, and infectious disease specialists, as well as other clinicians managing patients with suspected or laboratory-confirmed influenza. The guidelines consider the care of children and adults, including special populations such as pregnant and postpartum women and immunocompromised patients.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/cid/ciy866" target="_blank" rel="noreferrer noopener">10.1093/cid/ciy866</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Alexander Paul E
Bernstein Henry H
Bradley John S
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Department of Family & Community Medicine
Department of Internal Medicine
Englund Janet A
File Thomas M Jr
Fry Alicia M
Gravenstein Stefan
Harper Scott A
Hayden Frederick G
Hirshon Jon Mark
Ison Michael G
Johnston B Lynn
Knight Shandra L
McGeer Allison
NEOMED College of Medicine
Pavia Andrew T
Riley Laura E
Uyeki Timothy M
Wolfe Cameron R