Browse Items (22 total)
- Tags: Folkesson Hans G
Lung fluid absorption is induced in preterm guinea pigs ventilated with low tidal volumes.
Tags: *Premature Birth, *Tidal Volume, 2011, Absorption, Albumins/administration & dosage/*metabolism, Animals, Artificial/adverse effects/*methods, Beard LaMonta L, Enzyme Activation, Epinephrine/blood, Epithelial Sodium Channels/metabolism, Experimental lung research, Extracellular Signal-Regulated MAP Kinases/metabolism, Extravascular Lung Water/*metabolism, Fetal Organ Maturity, Folkesson Hans G, Gestational Age, Guinea Pigs, Hydrocortisone/blood, Intratracheal, Intubation, Koshy Shyny, Kuzenko Stephanie R, Li Tianbo, Lung/embryology/*metabolism/physiopathology, MAP Kinase Kinase Kinases/metabolism, Newborn, Permeability, Phosphorylation, Respiration, Sodium-Potassium-Exchanging ATPase/metabolism, Time Factors, Ventilator-Induced Lung Injury/metabolism/physiopathology/*prevention & control
RNA interference for CFTR attenuates lung fluid absorption at birth in rats.
Tags: *RNA Interference, 2008, Animals, Biological Transport/drug effects, Cells, Cultured, Cystic Fibrosis Transmembrane Conductance Regulator/*genetics/*metabolism, Epithelial Sodium Channels/genetics/metabolism, Female, Folkesson Hans G, Gene Expression Regulation/drug effects, Koshy Shyny, Li Tianbo, Lung/cytology/drug effects/*metabolism, Messenger/metabolism, Newborn, Pregnancy, Rats, Respiratory Mucosa/cytology/drug effects/metabolism, Respiratory research, RNA, Small Interfering/*pharmacology, Sprague-Dawley, Water/*metabolism
Stimulation of MAP kinase pathways after maternal IL-1beta exposure induces fetal lung fluid absorption in guinea pigs.
Tags: 2007, Absorption/drug effects, Animal/*metabolism, Animals, Beard LaMonta L, Bhattacharjee Reshma, Body Fluids/*metabolism, Carter Ethan P, Extracellular Signal-Regulated MAP Kinases/metabolism, Female, Fetus/metabolism, Folkesson Hans G, Garat Chrystelle, Gestational Age, Guinea Pigs, Hydrocortisone/*metabolism, Injections, Interleukin-1beta/administration & dosage/*pharmacology, Koshy Shyny, Li Tianbo, Lung/*embryology, Mitogen-Activated Protein Kinase Kinases/metabolism, Mitogen-Activated Protein Kinases/*metabolism, Pregnancy, Rats, Recombinant Proteins/administration & dosage/pharmacology, Respiratory research, Sharma Kapil, Subcutaneous
Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure.
Tags: 2009, Adrenergic, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/*metabolism, Body Fluids/*metabolism, Department of Integrative Medical Sciences, Epithelial Cells/drug effects/metabolism/pathology, Folkesson Hans G, Gene Expression Regulation/drug effects, Heart Failure/blood/diagnostic imaging/*metabolism/*pathology, Hormones/blood, Horne Walter I, Hyperplasia, Ion Channels/genetics/metabolism, Koshy Shyny, Li Tianbo, Luther Daniel J, Male, Maron Michael B, Messenger/genetics/metabolism, Meszaros J Gary, Myocardial Infarction/blood/diagnostic imaging/pathology, NEOMED College of Medicine, Ohanyan Vahagn, Pilati Charles F, Pulmonary Alveoli/drug effects/*pathology, Rats, Receptors, RNA, Sprague-Dawley, Terbutaline/pharmacology, Ultrasonography, Walro Jon M
IL-1beta-induced cortisol stimulates lung fluid absorption in fetal guinea pigs via SGK-mediated Nedd4-2 inhibition.
Tags: 2009, Absorption/drug effects, American journal of physiology. Lung cellular and molecular physiology, Animals, Base Sequence, Body Fluids/metabolism, DNA/genetics, Endosomal Sorting Complexes Required for Transport, Epithelial Sodium Channels/metabolism, Female, Folkesson Hans G, Guinea Pigs, Hydrocortisone/*biosynthesis/blood/physiology, Immediate-Early Proteins/genetics/*metabolism, Interleukin-1beta/*pharmacology, Koshy Shyny, Li Tianbo, Lung/*drug effects/*physiology, Molecular Sequence Data, Nedd4 Ubiquitin Protein Ligases, Pregnancy, Protein-Serine-Threonine Kinases/genetics/*metabolism, Recombinant Proteins/pharmacology, Ubiquitin-Protein Ligases/*antagonists & inhibitors/genetics
The adenosine 2A receptor agonist GW328267C improves lung function after acute lung injury in rats.
Tags: 2012, Acute Lung Injury/*drug therapy/metabolism/pathology, Adenosine A2A/*chemistry, Adenosine/*analogs & derivatives/therapeutic use, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Biological Transport, Bronchoalveolar Lavage, Cystic Fibrosis Transmembrane Conductance Regulator/metabolism, Endotoxemia/*drug therapy/metabolism/microbiology, Epithelial Sodium Channel Blockers, Epithelial Sodium Channels/metabolism, Escherichia coli, Escherichia coli Infections/drug therapy/metabolism/microbiology, Folkesson Hans G, Immunoblotting, Kuzenko Stephanie R, Lipson David A, Male, Matthay Michael A, Pneumonia/*drug therapy/metabolism/microbiology, Pulmonary Alveoli/cytology/*drug effects/metabolism, Pulmonary Edema/*drug therapy/metabolism/pathology, Rats, Receptor, Respiratory Physiological Phenomena, Simmons Mark A, Sodium Channel Blockers/pharmacology, Sprague-Dawley, Triazoles/*therapeutic use
Prolonged isoproterenol infusion impairs the ability of beta(2)-agonists to increase alveolar liquid clearance.
Tags: 2002, Adrenergic, Adrenergic beta-Agonists/*pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/metabolism, Boja John W, Down-Regulation/drug effects, Drug Interactions, Epithelial Cells/metabolism, Extravascular Lung Water/*metabolism, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/*pharmacology, Maender Kay C, Male, Maron Michael B, Morgan Eric E, Pulmonary Alveoli/cytology/*metabolism, Pulmonary Circulation/physiology, Pulmonary Edema/metabolism, Rats, Receptors, Respiratory Mucosa/cytology/*metabolism, Sprague-Dawley, Stader Sonya M, Terbutaline/pharmacology
Postreceptor defects in alveolar epithelial beta-adrenergic signaling after prolonged isoproterenol infusion.
Tags: 2003, 8-Bromo Cyclic Adenosine Monophosphate/pharmacology, Adenylyl Cyclases/metabolism, Adrenergic, Adrenergic beta-Agonists/*pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta/*metabolism, Colforsin/pharmacology, Cyclic AMP-Dependent Protein Kinase Type II, Cyclic AMP-Dependent Protein Kinases/metabolism, Cyclic AMP/metabolism, Extravascular Lung Water/metabolism, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/*pharmacology, Male, Maron Michael B, Mavrich Kate E, Morgan Eric E, Pulmonary Alveoli/*drug effects/*metabolism, Pulmonary Edema/metabolism, Rats, Receptors, Respiratory Mucosa/drug effects/metabolism, Signal Transduction/drug effects, Sprague-Dawley, Stader Sonya M
Oxytocin-induced labor augments IL-1beta-stimulated lung fluid absorption in fetal guinea pig lungs.
Tags: *Labor, 2005, Absorption/drug effects, American journal of physiology. Lung cellular and molecular physiology, Amiloride/administration & dosage, Animals, Bhattacharjee Reshma, Enzyme Activation/drug effects, Enzyme Inhibitors/administration & dosage, Epinephrine/metabolism, Extravascular Lung Water/*metabolism, Female, Fetal Organ Maturity/drug effects, Fetus/metabolism, Folkesson Hans G, Guinea Pigs, Hydrocortisone/metabolism, Induced, Interleukin-1/*administration & dosage/metabolism, Ion Transport/drug effects, Li Tianbo, Lung/*embryology, Maternal-Fetal Exchange/drug effects, Metyrapone/administration & dosage, Nair Prem K, Oxytocics/*administration & dosage, Oxytocin/*administration & dosage, Pregnancy, Propranolol/administration & dosage, Sodium Channel Blockers/administration & dosage, Sodium-Potassium-Chloride Symporters/metabolism, Vasodilator Agents/administration & dosage, Ye Xin
IL-1beta stimulates alveolar fluid absorption in fetal guinea pig lungs via the hypothalamus-pituitary-adrenal gland axis.
Tags: 2004, Acharya Reshma, Adrenocorticotropic Hormone/blood, American journal of physiology. Lung cellular and molecular physiology, Animals, Epinephrine/blood, Epithelial Sodium Channels, Extravascular Lung Water/*metabolism, Female, Folkesson Hans G, Guinea Pigs, Hamilton Sarah E, Herbert Jonathan B, Hydrocortisone/blood, Hypothalamo-Hypophyseal System/*physiology, Interleukin-1/blood/*pharmacology, Norepinephrine/blood, Pituitary-Adrenal System/*physiology, Pregnancy, Pulmonary Alveoli/*drug effects/embryology/*metabolism, Sodium Channels/metabolism, Sodium-Potassium-Exchanging ATPase/metabolism, Ye Xin
RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.
Tags: 2006, Absorption/drug effects, Adrenergic beta-Agonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Body Fluids/*metabolism, Capillary Permeability, Dose-Response Relationship, Drug, Endothelium, Epithelial Cells/metabolism, Epithelial Sodium Channels, Epithelium/metabolism, Folkesson Hans G, Inhibitory Concentration 50, Li Tianbo, Lung/enzymology/*metabolism, Male, Messenger/antagonists & inhibitors/metabolism, Permeability, Plasmids/administration & dosage/pharmacology, Rats, RNA, Small Interfering/genetics/pharmacology, Sodium Channels/drug effects/genetics/metabolism/*physiology, Sprague-Dawley, Terbutaline/pharmacology, Tissue Distribution, Vascular/metabolism
Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines.
Tags: 2002, Adrenergic beta-Antagonists/pharmacology, Aging/metabolism, American journal of physiology. Lung cellular and molecular physiology, Animals, Body Fluids/*metabolism, Body Water/metabolism, Catecholamines/*physiology, Chapin Cheryl J, Embryonic and Fetal Development, Epinephrine/blood, Epithelium/metabolism, Female, Fetus/drug effects/metabolism, Folkesson Hans G, Gestational Age, Kitterman Joseph A, Lung/drug effects/*embryology/metabolism, Male, Matthay Michael A, Newborn/metabolism, Porta Nicolas F M, Propranolol/pharmacology, Rats, Sprague-Dawley, Time Factors
Involvement of {alpha}ENaC and Nedd4-2 in the conversion from lung fluid secretion to fluid absorption at birth in the rat as assayed by RNA interference analysis.
Tags: *RNA Interference, 2007, Absorption, American journal of physiology. Lung cellular and molecular physiology, Animals, Body Fluids/*metabolism, Death, Endosomal Sorting Complexes Required for Transport, Epithelial Sodium Channels/genetics/*physiology, Extravascular Lung Water/metabolism, Folkesson Hans G, Gene Silencing, Koshy Shyny, Li Tianbo, Lung/*metabolism, Nedd4 Ubiquitin Protein Ligases, Newborn/*metabolism, Rats, RNA, Small Interfering/metabolism, Sodium-Potassium-Exchanging ATPase/metabolism, Sprague-Dawley, Tissue Distribution, Ubiquitin-Protein Ligases/genetics/metabolism/*physiology
PKA delivery to the distal lung air spaces increases alveolar liquid clearance after isoproterenol-induced alveolar epithelial PKA desensitization.
Tags: 2005, Adrenergic beta-Agonists/*pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, Body Fluids/physiology, Cyclic AMP-Dependent Protein Kinases/*administration & dosage, Desensitization, Extravascular Lung Water/metabolism, Folkesson Hans G, Immunologic, Isoproterenol/*pharmacology, Male, Maron Michael B, Pulmonary Alveoli/cytology/*drug effects/*metabolism, Pulmonary Circulation/physiology, Pulmonary Edema/metabolism, Rats, Respiratory Mucosa/cytology/drug effects/metabolism, Sprague-Dawley, Stader Sonya M, Walro Jon M
Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses.
Tags: *Gestational Age, *Hernias, 2006, Absorption, American journal of physiology. Lung cellular and molecular physiology, Amiloride/pharmacology, Animals, Beard LaMonta L, Body Fluids/*metabolism, Chapin Cheryl J, Congenital, Diaphragmatic, Diaphragmatic/*metabolism, Epinephrine/metabolism, Epithelial Sodium Channels, Ertsey Robert, Female, Fetal Organ Maturity, Fetus/*metabolism, Folkesson Hans G, Hernia, Kitterman Joseph A, Male, Matthay Michael A, Newborn, Phenyl Ethers/administration & dosage, Pregnancy, Propranolol/pharmacology, Rats, Respiratory System Abnormalities, Sodium Channels/metabolism, Sodium-Potassium-Exchanging ATPase/metabolism, Sprague-Dawley
Impaired alveolar liquid clearance after 48-h isoproterenol infusion spontaneously recovers by 96 h of continuous infusion.
Tags: *Pulmonary Alveoli/drug effects/metabolism, 2006, Adrenergic, Adrenergic beta-Antagonists/pharmacology, American journal of physiology. Lung cellular and molecular physiology, Animals, beta-2/metabolism, Bronchodilator Agents/administration & dosage/*pharmacology, Folkesson Hans G, Hodnichak Cheryl M, Isoproterenol/administration & dosage/*pharmacology, Lung/drug effects/metabolism, Male, Maron Michael B, Propranolol/pharmacology, Rats, Receptors, Sprague-Dawley, Stader Sonya M, Terbutaline/pharmacology, Time Factors
Type VI collagen induces cardiac myofibroblast differentiation: implications for postinfarction remodeling.
Tags: 2006, American journal of physiology. Heart and circulatory physiology, Angiotensin II/pharmacology, Animals, Cell Differentiation/*drug effects, Cell Proliferation/drug effects, Cells, Collagen Type I/physiology, Collagen Type III/physiology, Collagen Type VI/*physiology, Coronary Vessels/pathology, Cultured, Department of Integrative Medical Sciences, Doane Kathleen J, Extracellular Matrix/*physiology, Fibroblasts/*cytology, Fibrosis/etiology, Folkesson Hans G, Horne Walter I, Ligation, Male, Maron Michael B, Mase Sharon E, Meszaros J Gary, Myocardial Infarction/physiopathology, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Pilati Charles F, Rats, Sprague-Dawley, Ventricular Remodeling/*physiology, Zhang Xiaojin
A noninflammatory interleukin-1beta fragment stimulates fetal lung fluid absorption in guinea pigs.
Tags: 2007, Absorption, Adrenergic, Adrenocorticotropic Hormone/blood, Animals, Beard LaMonta L, beta/analysis, Body Fluids/drug effects/metabolism, Department of Integrative Medical Sciences, Epithelial Sodium Channels/genetics, Female, Fetus/drug effects, Folkesson Hans G, Guinea Pigs, Hydrocortisone/biosynthesis, Interleukin-1beta/*pharmacology, Li Tianbo, Lung/*drug effects/metabolism, Messenger/analysis, NEOMED College of Medicine, Oxytocin/pharmacology, Peptide Fragments/*pharmacology, Pregnancy, Receptors, RNA, The Journal of pharmacology and experimental therapeutics, Varadarajulu Shilpa, Yun June
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Anthocyanins/*therapeutic use, Anticarcinogenic Agents/therapeutic use, Apoptosis/drug effects, bcl-2-Associated X Protein/metabolism, Bishayee Anupam, Cell Proliferation/drug effects, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Down-Regulation, Experimental/metabolism/pathology, Folkesson Hans G, Haznagy-Radnai Erzsebet, Hohmann Judit, Liver Neoplasms, Liver Neoplasms/chemically induced/*prevention & control, Liver/pathology, Male, Mbimba Thomas, NEOMED College of Pharmacy, Phenobarbital, Plant Extracts/*therapeutic use, Proliferating Cell Nuclear Antigen/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Rats, Ribes/chemistry, Sipos Peter, Sprague-Dawley, The Journal of nutritional biochemistry, Thoppil Roslin J, Up-Regulation
Stimulation of distal airspace fluid clearance in guinea pigs involves bumetanide-sensitive ion transport.
Tags: *Ion Transport, 2004, Absorption, Adrenergic, Adrenergic beta-Antagonists/pharmacology, American journal of obstetrics and gynecology, Animals, beta/physiology, Body Fluids/*metabolism, Bumetanide/*pharmacology, Diuretics/*pharmacology, Epinephrine/blood, Epithelium, Fetus/metabolism, Folkesson Hans G, Gestational Age, Guinea Pigs, Lung/*embryology/metabolism, Newborn, Norlin Andreas, Propranolol/pharmacology, Receptors, Ye Xin
Fetal lung epithelial ion channels relocate in the cell membrane during late gestation.
Tags: 2011, Anatomical record (Hoboken, N.J. : 2007), Animals, Beard LaMonta L, Blotting, Caveolin 1/*metabolism, Cell Membrane/*metabolism, Cl transport, Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism, distal lung fluid absorption, Epithelial Sodium Channels/*metabolism, Epithelium/embryology/*metabolism, Female, fetal lung development, Fetus/*metabolism, Folkesson Hans G, Gestational Age, Guinea Pigs, Hu Yang, IL-1beta, Immunoprecipitation, Interleukin-1beta/metabolism, Ion Channels/metabolism, Li Tianbo, Lung/embryology/*metabolism, Na transport, Western