Body Weight And Composition Changes In Ovarian Cancer Patients During Adjuvant Chemotherapy
body composition; breast cancer; chemotherapy; gain; Obstetrics & Gynecology; Oncology; ovarian cancer; weight; women
Gil K M; Frasure H E; Hopkins M P; Jenison E L; Von Gruenigen V E
Gynecologic Oncology
2006
2006-10
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/j.ygyno.2006.03.005" target="_blank" rel="noreferrer noopener">10.1016/j.ygyno.2006.03.005</a>
Clinical disease course during the last year in ovarian cancer
carcinoma; chemotherapy; cytoreductive surgery; disease course; end; end-of-life; gynecologic cancer; Obstetrics & Gynecology; obstruction; of-life care; Oncology; ovarian-cancer; palliate; prognostic-factors; survival
Objective(s). The objective was to determine whether there were changes in the pattern and nature of hospitalizations during the last year that could be used in the assessment of whether chemotherapy should be continued. Methods. Retrospective data were collected from patients who died from ovarian cancer between 1/2000 and 12/2001. Charts from four hospitals were reviewed to abstract chemotherapy, reason for hospitalization, and the incidence of three significant clinical events (bowel obstruction, pleural effusion requiring thoracentesis, and abdominal ascites requiring paracentesis). Data were analyzed in 3-month intervals. Results. Sixty-two patient charts were reviewed. Quarterly admissions increased linearly over the year (7, 18, 27, and 47, P < 0.0001). Hospitalizations for ascites, bowel obstruction, and pleural effusion began increasing around 6 months preceding death. Twenty-two patients did not receive chemotherapy during the last 3 months. Of the 40 patients receiving chemotherapy in the last 3 months, over half were not hospitalized during the period 4-6 months before death, and a further 20% were hospitalized for nonsignificant clinical events. Approximately one-quarter of the patients, however, continued to receive chemotherapy following hospitalization for a significant clinical event. Conclusion(s). There were significant changes in the pattern and nature of hospitalization during the last 6 months that included hospitalizations for bowel obstruction, pleural effusion, or ascites. The occurrence of these events suggests that further chemotherapy should be realistically evaluated with the patient, which may reduce the number of patients who receive chemotherapy during their last few months of life. (C) 2003 Elsevier Inc. All rights reserved.
Von Gruenigen V E; Frasure H E; Reidy A M; Gil K M
Gynecologic Oncology
2003
2003-09
Journal Article
<a href="http://doi.org/10.1016/s0090-8258(03)00418-9" target="_blank" rel="noreferrer noopener">10.1016/s0090-8258(03)00418-9</a>
Complementary and alternative medicine use in the Amish.
*Christianity; Adult; Complementary Therapies/*statistics & numerical data; Female; Humans; Ohio; Phytotherapy/statistics & numerical data; Plant Preparations/therapeutic use; Pregnancy; Pregnancy Complications/therapy
OBJECTIVE: To examine the rate of utilization of complementary and alternative medicine (CAM) in Amish women, a population that traditionally uses non-mainstream medicine. METHODS & RESULTS: Sixty-six Amish women completed a survey concerning their use of CAM. Thirty-six percent of the Amish women used at least one form of CAM, primarily reporting a use of diet and nutrition programs, herbal therapies, and chiropractic medicine. In addition, ten pregnant Amish women reported using echinacea, St. John's Wort, red clover, garlic and ginseng. CONCLUSION: This survey highlights the need to address potential adverse effects of herbal therapies in young women who are a member of a group that may use non-mainstream medicine.
von Gruenigen V E; Showalter A L; Gil K M; Frasure H E; Hopkins M P; Jenison E L
Complementary Therapies in Medicine
2001
2001-12
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1054/ctim.2001.0485" target="_blank" rel="noreferrer noopener">10.1054/ctim.2001.0485</a>
Complementary and alternative medicine use in the Amish.
Adult; Female; Ohio; Self Report; Human; Surveys; Amish; Alternative Therapies – Utilization
Objective: To examine the rate of utilization of complementary and alternative medicine (CAM) in Amish women, a population that traditionally uses non-mainstream medicine. Methods & Results: Sixty-six Amish women completed a survey concerning their use of CAM. Thirty-six percent of the Amish women used at least one form of CAM, primarily reporting a use of diet and nutrition programs, herbal therapies, and chiropractic medicine. In addition, ten pregnant Amish women reported using echinacea, St. John's Wort, red clover, garlic and ginseng. Conclusion: This survey highlights the need to address potential adverse effects of herbal therapies in young women who are a member of a group that may use non-mainstream medicine. Copyright © 2002 by Elsevier Science (USA).
von Gruenigen V E; Showalter A L; Gil K M; Frasure H E; Hopkins M P; Jenison E L
Complementary Therapies in Medicine
2001
2001-12
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1054/ctim.2001.0485" target="_blank" rel="noreferrer noopener">10.1054/ctim.2001.0485</a>
Longitudinal assessment of quality of life and lifestyle in newly diagnosed ovarian cancer patients: The roles of surgery and chemotherapy
alternative medicine use; behaviors; breast-cancer; chemotherapy; complementary and alternative medicine; complementary/alternative; energy-balance; functional assessment; gynecologic; medicine; Obstetrics & Gynecology; Oncology; Oncology; ovarian-cancer; quality-of-life; receiving adjuvant chemotherapy; Surgery; trial; women
Objectives. To prospectively evaluate quality of life (QoL), use of complementary and alternative medicine (CAM), and diet/exercise changes in ovarian cancer patients during the first 6 months following diagnosis. Methods. Patients with newly diagnosed ovarian cancer were enrolled pre- or post-operatively and surveyed at 3 and 6 months. The Functional Assessment of Cancer Therapy (FACT-G), Medical Outcomes Survey (SF-36), and CAM/diet/exercise questionnaires were used. Independent samples t test and repeated measures ANOVA were used. Results. Forty-two patients underwent surgical debulking and staging prior to chemotherapy. Patients completing the initial surveys post-operatively had significantly lower physical FACT-G and SF-36 physical scores compared to patients completing the surveys pre-operatively. In patients completing the baseline survey pre-operatively, there was a decrease in physical scores at 3 months (after surgery and during chemotherapy). There was no change observed at 3 months relative to baseline when patients completed the baseline survey post-operatively. Increases in physical and functional well-being were seen at 6 months relative to 3 months. There were no changes in emotional or social scores over time. CAM use increased over time; main reasons were to improve QoL and relieve symptoms. Alterations in diet and exercise were not seen. Conclusions. These data highlight the need to conduct assessments before and after surgery to identify effects due to surgery and/or chemotherapy. Patients may be using CAM during chemotherapy to deal with symptoms and compensate for decreased QoL. Intervention trials should be implemented to increase QoL following surgery and during adjuvant chemotherapy. (c) 2006 Elsevier Inc. All rights reserved.
Von Gruenigen V E; Frasure H E; Jenison E L; Hopkins M P; Gil K M
Gynecologic Oncology
2006
2006-10
Journal Article
<a href="http://doi.org/10.1016/j.ygyno.2006.01.059" target="_blank" rel="noreferrer noopener">10.1016/j.ygyno.2006.01.059</a>
Patient Characteristics Influencing Quality Of Life In Gynecologic Cancer
Oncology
Gil K; Frasure H E; Jenison E; Hopkins M; Von Gruenigen V E
Journal of Clinical Oncology
2006
2006-06
Journal Article or Conference Abstract Publication
n/a
Simultaneous Measurement Of Cancer Specific Quality Of Life And General Health Status In Gynecologic Malignancies
Oncology
Gil K M; Von Gruenigen V E; Frasure H E; Grandon M; Hopkins M P; Jenison E L
Journal of Clinical Oncology
2004
2004-07
Journal Article or Conference Abstract Publication
n/a
The impact of obesity and age on quality of life in gynecologic surgery
adults; anemic cancer-patients; body-mass index; complications; Elderly; endometrial cancer; epoetin-alpha; gynecologic surgery; life; morbidity; obesity; Obstetrics & Gynecology; population; quality of; sf-36; trial; validation
Objective: This study was undertaken to prospectively evaluate the effect of early stage endometrial cancer, age, and obesity on quality of life (QOL). Study design: Women undergoing surgery for endometrial cancer or an adnexal mass determined at surgery to be benign (controls) were enrolled preoperatively and followed for 6 months. Results: Seventy-nine women completed the study. Functional Assessment of Cancer Therapy (FACT-G) scores increased significantly in all women; however, significant differences by patient weight and age were obtained. Obesity was associated with decreased physical FACT-G and SF-36 scores. Older women had lower SF-36 physical scores, higher emotional scores, and less change over time. Conclusion: Women with early endometrial cancer had similar changes in QOL as those who received surgery for benign disease. Obese and elderly women had domain alterations. Given the aging population and rising incidence of obesity, these results emphasize the need for QOL interventions in postoperative gynecologic care of these patients. (C) 2005 Mosby, Inc. All rights reserved.
Von Gruenigen V E; Gil K M; Frasure H E; Jenison E L; Hopkins M P
American Journal of Obstetrics and Gynecology
2005
2005-10
Journal Article
<a href="http://doi.org/10.1016/j.ajog.2005.03.038" target="_blank" rel="noreferrer noopener">10.1016/j.ajog.2005.03.038</a>