1
40
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">http://doi.org/10.3390/microorganisms8040490</a>
Issue
4
Volume
8
ISSN
2076-2607 2076-2607
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.3390/microorganisms8040490</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
June 2020 Update I
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The Microbiota-Gut-Brain Axis Heart Shunt Part I: The French Paradox, Heart Disease and the Microbiota.
Publisher
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Microorganisms
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-03-30
Subject
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Alzheimer; blood brain barrier; Celiac disease; cerebrovascular; co-metabolism; French paradox; heart brain shunt; HMG-Co A; leaky gut; microbiota-gut-brain axis; polyphenol; red wine; redox; TMANO; TMAO; Trimethyl-Amine-N-Oxide; vascular dementia
Creator
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Obrenovich Mark; Siddiqui Bushra; McCloskey Benjamin; Reddy V Prakash
Description
An account of the resource
It has been well established that a vegetarian and polyphenol-rich diet, including fruits, vegetables, teas, juices, wine, indigestible fiber and whole grains, provide health-promoting phytochemicals and phytonutrients that are beneficial for the heart and brain. What is not well-characterized is the affect these foods have when co-metabolized within our dynamic gut and its colonizing flora. The concept of a heart shunt within the microbiota-gut-brain axis underscores the close association between brain and heart health and the so-called "French paradox" offers clues for understanding neurodegenerative and cerebrovascular diseases. Moreover, oxidation-redox reactions and redox properties of so-called brain and heart-protective foods are underappreciated as to their enhanced or deleterious mechanisms of action. Focusing on prodromal stages, and common mechanisms underlying heart, cerebrovascular and neurodegenerative diseases, we may unmask and understanding the means to better treat these related diseases.
Identifier
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<a href="http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">10.3390/microorganisms8040490</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
Alzheimer
blood brain barrier
celiac disease
cerebrovascular
co-metabolism
French paradox
heart brain shunt
HMG-Co A
Journal Article
journalArticle
June 2020 Update I
leaky gut
McCloskey Benjamin
microbiota-gut-brain axis
microorganisms
NEOMED College of Medicine Student
NEOMED Student Publications
Obrenovich Mark
polyphenol
red wine
Reddy V Prakash
Redox
Siddiqui Bushra
TMANO
TMAO
Trimethyl-Amine-N-Oxide
vascular dementia
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3390/microorganisms8040493" target="_blank" rel="noreferrer noopener">http://doi.org/10.3390/microorganisms8040493</a>
Issue
4
Volume
8
ISSN
2076-2607 2076-2607
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.3390/microorganisms8040493" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.3390/microorganisms8040493</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
June 2020 Update I
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease.
Publisher
An entity responsible for making the resource available
Microorganisms
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-03-31
Subject
The topic of the resource
Alzheimer disease; brain; cerebrovascular; co-metabolism; French paradox; heart; microbiota-gut-brain axis; Parkinson's disease; polyphenol; prosaic foods; red wine; trimethylamine-N-oxide (TMANO/TMAO)
Creator
An entity primarily responsible for making the resource
Obrenovich Mark; Tabrez Shams; Siddiqui Bushra; McCloskey Benjamin; Perry George
Description
An account of the resource
There is a strong cerebrovascular component to brain aging, Alzheimer disease, and vascular dementia. Foods, common drugs, and the polyphenolic compounds contained in wine modulate health both directly and through the gut microbiota. This observation and novel findings centered on nutrition, biochemistry, and metabolism, as well as the newer insights we gain into the microbiota-gut-brain axis, now lead us to propose a shunt to this classic triad, which involves the heart and cerebrovascular systems. The French paradox and prosaic foods, as they relate to the microbiota-gut-brain axis and neurodegenerative diseases, are discussed in this manuscript, which is the second part of a two-part series of concept papers addressing the notion that the microbiota and host liver metabolism all play roles in brain and heart health.
Identifier
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<a href="http://doi.org/10.3390/microorganisms8040493" target="_blank" rel="noreferrer noopener">10.3390/microorganisms8040493</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2020
Alzheimer disease
Brain
cerebrovascular
co-metabolism
French paradox
heart
Journal Article
journalArticle
June 2020 Update I
McCloskey Benjamin
microbiota-gut-brain axis
microorganisms
NEOMED College of Medicine Student
NEOMED Student Publications
Obrenovich Mark
Parkinson's disease
Perry George
polyphenol
prosaic foods
red wine
Siddiqui Bushra
Tabrez Shams
trimethylamine-N-oxide (TMANO/TMAO)