Background. Obesity can be divided into "general" and "central." Since abnormal glucose and lipid metabolism are more strongly associated with central obesity, it may not be adequate to use a general measure, such as weight-for-height index, to…
Two generations of amphiphilic membranes synthesized in our laboratories for biologicaUniedical applications are highlighted. Recent results obtained with representative 2nd generation membranes designed specifically for immunoencapsulation of…
Middle cerebral artery occlusion (MCAO) is a popular model in experimental stroke research and causes prominent ischemic damage in the forebrain. To characterize metabolic changes induced by MCAO, we have induced permanent MCAO in mice that were…
Growth hormone (GH) is a key metabolic regulator mediating glucose and lipid metabolism. Ataxia telangiectasia mutated (ATM) is a member of the phosphatidylinositol 3-kinase superfamily and regulates cell cycle progression. The orphan nuclear…
Neuroprotective properties of bilobalide, a specific constituent of Ginkgo extracts, were tested in a mouse model of stroke. After 24 h of middle cerebral artery occlusion (MCAO), bilobalide reduced infarct areas in the core region (striatum) by…
