Browse Items (5 total)
- Tags: GPNMB
Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.
Tags: 2018, Animals, Budge Kevin M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, GPNMB, Humans, Immune System/metabolism, Membrane Glycoproteins/chemistry/*metabolism, Molecular neurobiology, Neal Matthew L, NEOMED College of Medicine, NEOMED College of Pharmacy, Nerve Degeneration/pathology, Neurodegeneration, Neurodegenerative Diseases/*metabolism/therapy, Neuroinflammation, Neuroprotection, Richardson Jason R, Safadi Fayez F
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.
Tags: 2018, Astrocyte, Boyle Alexa M, Budge Kevin M, CD44, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, GPNMB, Journal of neuroinflammation, Neal Matthew L, NEOMED College of Medicine, NEOMED College of Pharmacy, Neuroinflammation, Parkinson's disease, Richardson Jason R, Safadi Fayez F
Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells.
Tags: *Cell Movement, *Cell Proliferation, 2016, Animals, Apoptosis, Biomarkers, Carcinoma, Cell Adhesion, Cultured, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Female, GPNMB, Humans, integrin, Lung cancer, Lung Neoplasms/metabolism/*pathology, Manickavasagam Dharani, Membrane Glycoproteins/*metabolism, Mice, Moussa Fouad M, NEOMED College of Medicine, NEOMED College of Pharmacy, Neoplasm Invasiveness, Non-Small-Cell Lung/metabolism/*pathology, Novak Kimberly, NSCLC, Nude, Oncotarget, Oyewumi Moses O, Paulic Nikola, Protein Domains, Safadi Fayez F, Sondag Gregory R, Tumor Cells, Tumor/*metabolism, Wehrung Daniel, Xenograft Model Antitumor Assays
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor.
Tags: *Neuroinflammation, *Parkinson's disease, 1-Methyl-4-phenyl-1, 2, 2018, 3, 6-tetrahydropyridine/pharmacology, Analysis of Variance, Animals, Anti-Inflammatory Agents/*therapeutic use, Astrocyte, Astrocytes/*drug effects, Boyle Alexa M, Budge Kevin M, Case-Control Studies, CD44, Cells, Chemical, Cultured, Cytokines/genetics/metabolism, Databases, Female, Glial Fibrillary Acidic Protein/metabolism, GPNMB, Humans, Hyaluronan Receptors/*metabolism, Inflammation/*drug therapy/etiology, Journal of neuroinflammation, Male, Membrane Glycoproteins/*therapeutic use, Messenger/metabolism, Mice, Neal Matthew L, Neurotoxins/toxicity, Nitric Oxide/metabolism, Parkinson Disease/complications/*pathology, Reactive Oxygen Species/metabolism, Richardson Jason R, RNA, Safadi Fayez F, Signal Transduction/drug effects
Transgenic Overexpression of GPNMB Protects Against MPTP-Induced Neurodegeneration.
Tags: 2020, Budge Kevin, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, GPNMB, journalArticle, June 2020 Update II, Microglia, Molecular neurobiology, MPTP, Neal Matthew L, NEOMED College of Medicine, NEOMED College of Pharmacy, Neuroinflammation, Neuroprotective, Parkinson's disease, Richardson Jason R, Safadi Fayez F