Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.
Female; Humans; Infant; Pregnancy; *Magnetic Resonance Imaging; Heroin/*adverse effects; Narcotics/*adverse effects; *Prenatal Exposure Delayed Effects; Child Development/drug effects; Cocaine/*adverse effects; Failure to Thrive/chemically induced/etiology; Substance-Related Disorders/*diagnosis/etiology; Substantia Nigra/drug effects/*pathology; Cardiomyopathy; Dilated/chemically induced/*diagnosis
Exposure to cocaine in utero results in behavioral and neurodevelopmental abnormalities that persist into adulthood. Conventional MR imaging has generally failed to reveal the expected structural lesions to explain these clinical findings. We report a case of focal MR imaging signal-intensity changes in the substantia nigra, locus ceruleus, and other selected nerve tracts and nuclei in a child exposed prenatally to cocaine and other drugs. The patient also had dilated cardiomyopathy.
Arnold R; Johnson C; McNulty B; Gaisie G
AJNR. American journal of neuroradiology
2008
2008-04
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.3174/ajnr.A0966" target="_blank" rel="noreferrer noopener">10.3174/ajnr.A0966</a>
Increased Renal Parenchymal Echogenicity - Causes In Pediatric-patients
Nuclear Medicine & Medical Imaging; Radiology
Kraus R A; Gaisie G; Young L W
Radiographics
1990
1990-11
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1148/radiographics.10.6.2259758" target="_blank" rel="noreferrer noopener">10.1148/radiographics.10.6.2259758</a>