Browse Items (27 total)
- Tags: Genes
230. Molecular Typing of Streptococcus pyogenes Isolates Collected at Mongolian Hospital (Ulaanbaatar, Mongolia).
Tags: 2019, antibiotic resistance, antimicrobial susceptibility, Bacterial, CENTERS for Disease Control & Prevention (U.S.), China, clone cells, Communicable Diseases, Davaadash Bulgan, Disclosure, Disease Outbreaks, DRUG resistance in bacteria, Epidemiology, Genes, ichthyosis, Infection, Journal Article, Kadariya Jhalka, low income, LOW-income countries, Mackey Samantha, Medical, Molecular, MOLECULAR epidemiology, Mongolia, Morbidity, Mortality, multi-antibiotic resistance, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Open forum infectious diseases, Polymerase Chain Reaction, sequence tagged sites, Smith Tara, sodium thiosulfate, Streptococcus pyogenes, surveillance, Thapaliya Dipendra, TOXIC shock syndrome, ULAANBAATAR (Mongolia), vaccine development, x-linked
Hepatic Cannabinoid Receptor Type 1 Mediates Alcohol-Induced Regulation of Bile Acid Enzyme Genes Expression Via CREBH
Tags: 2013, Acids, activation, Ahn S H, Alcohol, Alcohols, Bile, BILE acids, bound, cb1 receptors, Chanda D, Chiang J Y L, Choi H S, cholesterol 7-alpha-hydroxylase, Damage prevention, Deregulation, Diabetes Mellitus, element-binding protein, endocannabinoid system, endoplasmic-reticulum stress, er stress, exposure, Fatty Liver, gene-expression, Genes, hepatocytes, Homeostasis, human hepatocytes, insulin, insulin-resistance, Jeong W I, Journal Article or Conference Abstract Publication, Kim D K, Kim J R, Kim Y H, Koo S H, Kwon J, Lee C H, leptin resistance, Li T, Liver, Liver Diseases, Metabolism, Mice, Misra J, Muridae, Ohio, Park T S, PloS one, Regulatory mechanisms (biology), RNA extraction, Rodents, Science & Technology - Other Topics, Sciences: Comprehensive Works, Signal Transduction, Signaling, Synthesis, transcription factor
Identification of Multiple Metabolic Enzymes from Mice Cochleae Tissue Using a Novel Functional Proteomics Technology
Tags: 2015, Animal tissues, Bao J X, Beef, Biology, Cancer, cancer metabolism, cell metabolism, Cochlea, draft, Drug Therapy, E coli, Electrophoresis, Elution, Enzymatic activity, Enzyme assays, Enzyme metabolism, Enzymes, Feasibility Studies, Functional analysis, Gel electrophoresis, Genes, Genomics, Hearing impairment, Journal Article, Kinases, Li H, Liang R Q, Mass spectrometry, Mass spectroscopy, Medicine, messenger-rna, Metabolism, Mice, NAD(P)H oxidase, NADH, Neurobiology, Neurosciences, nicotinamide adenine dinucleotide, Noise, otolaryngology, Oxidation-reduction reactions, Phosphatase, PloS one, PROTEIN expression, Proteins, Proteomes, proteomics, Science & Technology - Other Topics, Sciences: Comprehensive Works, Scientific imaging, Studies, Substance abuse treatment, Technology, United States--US, Wang D L
Tags: 2005, Afrotheria, base composition, Biochemistry & Molecular Biology, elements, endemic african mammals, Evolution, Evolutionary Biology, Genes, Genetics &, Heredity, Journal Article, mammalian phylogeny, mitochondrial genomes, Molecular Biology and Evolution, molecular evidence, Nikaido M, Nishihara H, Okada N, Paenungulata, placental mammals, retroposons, Satta Y, SINEs, Stanhope M J, Support, Tethytheria, Thewissen J G M
Tags: 2019, aldosteronism, Amin Harshesh, apparent mineralocorticoid excess, congenital adrenal hyperplasia, Das Abhijit, Department of Internal Medicine, Disease, familial, familial hyperaldosteronism, features, Frontiers in pediatrics, Genes, Gordon syndrome, hyperaldosteronism, Krishnappa Vinod, Kusumi Kirsten, Liddle syndrome, mineralocorticoid excess, monogenic hypertension, mutations, Nair Nikhil R, NEOMED College of Graduate Studies Student, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Pediatrics, Prevalence, Radhakrishnan Yeshwanter, Raina Rupesh, September 2019 Update, stroke, update
Tags: 2008, Animal Population Groups, Animal Studies, Biological Transport – Drug Effects, Cells, Female, Folkesson H G, Genes, Genes – Drug Effects, Koshy S, Li T, Lung, Lung – Drug Effects, Lung – Metabolism, Membrane Proteins – Metabolism, Pregnancy, Rats, Respiratory Mucosa, Respiratory Mucosa – Drug Effects, Respiratory Mucosa – Metabolism, Respiratory research, RNA – Metabolism, RNA – Pharmacodynamics, Water – Metabolism
Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells.
Tags: *Promoter Regions, *Transcription, *Transcription Factors, 1996, Base Sequence, Binding Sites, Cell Line, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics, Consensus Sequence, Crestani M, Department of Integrative Medical Sciences, DNA-Binding Proteins/genetics/metabolism, Enzyme Repression, Enzymologic/*drug effects, Galli G, Gene Expression Regulation, Genes, Genetic, Glucocorticoid/genetics/metabolism, Glucocorticoids/pharmacology, Hepatocyte Nuclear Factor 3-alpha, Humans, Insulin/pharmacology, Journal of lipid research, Marrapodi M, Molecular Sequence Data, NEOMED College of Medicine, Nuclear Proteins/genetics/metabolism, Phorbol Esters/pharmacology, Receptors, Recombinant Fusion Proteins/biosynthesis, Reporter, Stroup D, Thyroid Hormones/pharmacology, Transfection, Wang D P
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
Tags: *Receptors, *Transcription, 2000, Animals, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, COUP Transcription Factor II, COUP Transcription Factors, Cultured, Department of Integrative Medical Sciences, DNA Primers, DNA-Binding Proteins/*metabolism, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Luciferases/genetics, Mutation, NEOMED College of Medicine, Phosphoproteins/*metabolism, Promoter Regions, Rats, Recombinant Proteins/metabolism, Reporter, Sprague-Dawley, Steroid, Stroup D, Transcription Factors/*metabolism, Tumor Cells
Tags: *Peritoneal Dialysis, 1995, Adult, Asfoura J Y, Continuous Ambulatory, Cysts/*complications/genetics/surgery, Department of Internal Medicine, Dominant, Follow-Up Studies, Genes, Hemoperitoneum/*etiology, Humans, Laparotomy, Liver Diseases/*complications/genetics/surgery, Male, NEOMED College of Medicine, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, Rutecki G W, Whittier F C
Peroxisome proliferator-activated receptor alpha (PPARalpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription.
Tags: *DNA-Binding Proteins, *Regulatory Sequences, 2000, Animals, Anticholesteremic Agents/pharmacology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Binding Sites, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/biosynthesis/*genetics, Clofibric Acid/pharmacology, Cytoplasmic and Nuclear/*agonists, Department of Integrative Medical Sciences, Enzymologic, Gene Expression Regulation, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Marrapodi M, Models, NEOMED College of Medicine, Nucleic Acid, Peroxisome Proliferators/pharmacology, Phosphoproteins/metabolism, Promoter Regions, Protein Binding, Pyrimidines/pharmacology, Rats, Receptors, Reporter, Response Elements, Retinoic Acid/metabolism, Retinoid X Receptors, Species Specificity, Transcription, Transcription Factors/*agonists/metabolism, Transcriptional Activation
Tags: 1988, Amino Acid Sequence, Animals, Base Sequence, Chromosome Deletion, Cloning, Cytochrome b Group/*genetics, Cytochromes b5, Dariush N, Fisher C W, Genes, Liver/*metabolism, Messenger/*genetics, Molecular, Molecular Sequence Data, Protein sequences & data analysis, Rabbits, RNA, Steggles A W
Transcriptional activation of the cholesterol 7alpha-hydroxylase gene (CYP7A) by nuclear hormone receptors.
Tags: *Receptors, *Transcriptional Activation, 1998, Animals, Base Sequence, Bile Acids and Salts/biosynthesis, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, COUP Transcription Factor II, COUP Transcription Factors, Crestani M, Cultured, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, DNA/metabolism, Galli G, Genes, Genetic, Hepatocyte Nuclear Factor 4, Hormones/*physiology, Journal of lipid research, Luciferases/genetics, Molecular Sequence Data, Mutagenesis, NEOMED College of Medicine, Nucleic Acid, Oligonucleotide Probes/metabolism, Phosphoproteins/metabolism, Promoter Regions, Rats, Receptors, Repetitive Sequences, Reporter, Retinoic Acid/metabolism, Retinoid X Receptors, Sadeghpour A, Site-Directed, Steroid, Stroup D, Transcription Factors/metabolism, Tumor Cells
Intrastrain variants of herpes simplex virus type 1 isolated from a neonate with fatal disseminated infection differ in the ICP34.5 gene, glycoprotein processing, and neuroinvasiveness.
Tags: *Genetic Variation, *Protein Processing, 1999, Amino Acid, Amino Acid Sequence, Animal, Animals, Base Sequence, Bower J R, Deoxyribonuclease BamHI, Deoxyribonuclease EcoRI, Detwiler M, Disease Models, DNA, Durishin C, Genes, Glycoproteins/metabolism, Herpesvirus 1, Human/*genetics/growth & development/isolation & purification, Humans, Inbred BALB C, Journal of virology, Karban T L, Male, Mao H, Mice, Molecular Sequence Data, Nucleic Acid, Polymerase Chain Reaction/methods, Polymorphism, Post-Translational, Rempinski D, Restriction Fragment Length, Rosenthal K S, Rozenbom E, Sequence Analysis, Sequence Homology, Viral, Viral Envelope Proteins/analysis, Viral Proteins/*genetics
Tags: *Lipid Metabolism, 2007, ATP Binding Cassette Transporter, ATP Binding Cassette Transporter 1, ATP-Binding Cassette Transporters/genetics, Base Sequence, Cell Line, Chen Wenling, Chiang John Y L, Cholestanetriol 26-Monooxygenase/*metabolism, Cholesterol, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Fluorinated, Genes, Genetic/drug effects, Genetic/genetics, HDL/metabolism, Hepatocytes/drug effects/enzymology/metabolism, Humans, Hydrocarbons, Hydroxycholesterols/metabolism/pharmacology, Intestinal Mucosa/metabolism, Intestines/cytology/drug effects/enzymology, Journal of lipid research, Li Tiangang, Member 1, Messenger/genetics/metabolism, Molecular Sequence Data, NEOMED College of Medicine, Pregnane X Receptor, Promoter Regions, Receptors, Reporter, Response Elements/genetics, Rifampin/pharmacology, RNA, Steroid/*metabolism, Subfamily G, Sulfonamides/pharmacology, Transcription, Up-Regulation/drug effects
Tags: *Gene Expression Regulation, 2010, Acetylation, AMP-Activated Protein Kinases/metabolism, ATP Citrate (pro-S)-Lyase/genetics/metabolism, Bile Acids and Salts/metabolism, Cells, Chanda Dipanjan, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Enzymologic, Epigenesis, Genes, Genetic, Glucose/*administration & dosage, Hep G2 Cells, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/*enzymology/metabolism, Histones/metabolism, Humans, Hyperglycemia/enzymology/*metabolism, Journal of lipid research, Li Tiangang, Messenger/metabolism, Methylation, NEOMED College of Medicine, Reporter, RNA, RNA Interference, Zhang Yanqiao
Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy.
Tags: 2018, Alzheimer's disease, Animal, Animals, Antigens, Bemiller Shane M, Bhaskar Kiran, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cannon Judy L, Cardona Astrid E, Cells – Drug Effects, Cells – Metabolism, Cells – Pathology, Chemokine CX3CL1/*genetics/metabolism, Cognition Disorders – Etiology, Cognition Disorders/etiology, Crish Samuel D, CX3CL1, CX3CR1, Cytokines, Cytokines – Metabolism, Cytokines/metabolism, Department of Pharmaceutical Sciences, Differentiation/genetics/metabolism, Disease Models, Formica Shane V, Gene Expression Regulation/drug effects/*genetics, Genes, Genes – Drug Effects, Journal of neuroinflammation, Jung Steffen, Kim Ki-Wook, Kokiko-Cochran Olga N, Lamb Bruce T, Learning, Lipopolysaccharides, Lipopolysaccharides/toxicity, Maphis Nicole M, Maze Learning, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia, Microglia/drug effects/*metabolism/pathology, Miller Crystal M, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurodegenerative Diseases – Pathology, Neuroinflammation, Surface, Surface – Metabolism, Tau, tau Proteins/genetics/metabolism, Tauopathies, Tauopathies/complications/genetics/*pathology, Transgenic, Wilson Gina N, Xu Guixiang
Analyzing the most frequent disease loci in targeted patient categories optimizes disease gene identification and test accuracy worldwide.
Tags: *Genetic Loci, *Genetic Predisposition to Disease, 2015, Adult, Child, Chromosomes, Disease/*genetics, European Continental Ancestry Group, Female, Genes, Genetic Testing/*methods, Genetics, Heterozygote, Human/genetics, Humans, Infant, Journal of translational medicine, Lebo Roger V, Newborn, Population, Pregnancy, Prenatal Diagnosis, Rare Diseases/genetics, Recessive, Tonk Vijay S
LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model.
Tags: *Cancer Vaccines/genetics/immunology/therapeutic use, 2017, Animal, Animals, Breast Neoplasms/genetics/immunology/prevention & control/therapy, CD8-Positive T-Lymphocytes/immunology, Cell Line, Cytotoxic/immunology, Disease Models, Disease Progression, Epitopes, erbB-2, Experimental/immunology/pathology/*prevention & control/*therapy, Female, Genes, Immunoglobulin G/blood, Inbred BALB C, Journal of immunology research, Koski Gary, Mammary Neoplasms, Mice, Neoplasm Metastasis/prevention & control, Proof of Concept Study, Rosenthal Ken S, Stone Sarah, T-Lymphocyte/immunology, T-Lymphocytes, Tumor, Zimmerman Daniel H
Tags: 1997, Animals, Base Sequence, Bile Acids and Salts/*pharmacology, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Feedback, Genes, Genes/*drug effects, Luciferases/genetics, NEOMED College of Medicine, Rats, Reporter, Stroup D, The American journal of physiology, Tumor Cells
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
Tags: *Punicaceae/chemistry, 10-Dimethyl-1, 2-benzanthracene, 2016, 9, Animal Studies, Animals, Anticarcinogenic Agents/*therapeutic use, Apoptosis, Apoptosis/*drug effects, Bhatia Deepak, Bhattacharyya Piyali, Bishayee Anupam, Breast Neoplasms – Mortality, Breast Neoplasms – Prevention and Control, Breast Neoplasms – Risk Factors, Cell Physiology, Cell Proliferation/*drug effects, Diet – Evaluation, Experimental/pathology/*prevention & control, Female, Funding Source, Gene Expression Regulation, Genes, Human, Immunohistochemistry, Mammary Neoplasms, Mandal Animesh, Mutation, National Institutes of Health (U.S.), Neoplasms – Prevention and Control, Nutrition and cancer, Phytotherapy, Pomegranate, Proto-Oncogene Proteins c-bcl-2/analysis, Rats, Sprague-Dawley, Tamoxifen, United States
A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.
Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques
Cardiovascular Effects of Exposure to Cigarette Smoke and Electronic Cigarettes: Clinical Perspectives From the Prevention of Cardiovascular Disease Section Leadership Council and Early Career Councils of the American College of Cardiology.
Tags: 2015, Al-Mallah Mouaz H, atherogenesis, Bahrami Hossein, Benowitz Neal L, Bhakta Shyam, Cardiovascular Diseases – Etiology, Cardiovascular Diseases/*etiology, Deedwania Prakash, Department of Internal Medicine, El-Chami Mikhael F, Electronic Cigarettes – Adverse Effects, Electronic Nicotine Delivery Systems/*adverse effects, Epigenesis, Feldman Dmitriy N, Ference Brian A, Genes, Genetic, genetic and epigenetic effects, Humans, Impact of Events Scale, Jahangir Eiman, Journal of the American College of Cardiology, Mehta Laxmi S, Morris Pamela B, NEOMED College of Medicine, Phan Binh An P, Ryan John J, Sanchez Shields Monica, Scales, smoke-free legislation, Smoking – Complications, Smoking – Legislation and Jurisprudence – United States, Smoking Cessation, Smoking/*adverse effects/legislation & jurisprudence, Thrombosis, tobacco cessation, United States, Winchester David E
Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.
Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong
Promoter activity and regulation of the CYP4F2 leukotriene B(4) omega-hydroxylase gene by peroxisomal proliferators and retinoic acid in HepG2 cells.
Tags: *Gene Expression Regulation, *Promoter Regions, 2000, Amino Acid Sequence, Archives of biochemistry and biophysics, Base Sequence, Cell Line, Chen L, Cloning, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 4, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, DNA, DNA Footprinting, Enzymologic, Exons, Genes, Genetic, Genetic/drug effects, Hardwick J P, Humans, Introns, Leukotriene B4/metabolism, Mixed Function Oxygenases/metabolism, Models, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Peroxisome Proliferators/*metabolism, Receptors, Reporter, Retinoic Acid Receptor alpha, Retinoic Acid/metabolism, Sequence Analysis, Transcription, Transcription Factors/metabolism, Transfection, Tretinoin/*metabolism, Zhang X