Browse Items (51 total)
- Tags: Genetic
Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.
Tags: 1994, 5-Hydroxytryptophan/pharmacology, alpha-Methyltyrosine, Animals, Anterior/*chemistry/drug effects/metabolism, Blotting, Bromocriptine/pharmacology, Carrillo A J, Gene Expression Regulation/drug effects/physiology, Genetic, Haloperidol/pharmacology, Ketanserin/pharmacology, Liu B, Male, Messenger/*analysis/genetics, Methiothepin/pharmacology, Methoxydimethyltryptamines/pharmacology, Methyltyrosines/pharmacology, Molecular and cellular endocrinology, Northern, Pituitary Gland, Prolactin/analysis/*genetics/metabolism, Quipazine/pharmacology, Rats, RNA, Serotonin/*physiology, Signs S A, Sprague-Dawley, Time Factors, Transcription, Vasoactive Intestinal Peptide/analysis/*genetics/metabolism, Wolford J
The human liver and reticulocyte cytochrome b5 mRNAs are products from a single gene.
Tags: *Genes, 1991, Amino Acid Sequence, Base Sequence, Biochemical and biophysical research communications, Cytochromes b5/blood/*genetics, Gene Library, Genetic, Giordano S J, Humans, Liver/*metabolism, Molecular Sequence Data, Polymerase Chain Reaction, Polymorphism, Reticulocytes/*metabolism, RNA/blood/genetics/isolation & purification, Steggles A W
The isolation and characterization of the bovine cytochrome b5 gene, and a transcribed pseudogene.
Tags: *Pseudogenes, 1993, Amino Acid Sequence, Animals, Base Sequence, Blotting, Cattle/*genetics, Cristiano R J, Cytochromes b5/*genetics, DNA/genetics/isolation & purification, Exons, Gene Expression, Genetic, Genomic Library, Genomics, Giordano S J, Humans, Introns, Messenger/biosynthesis/metabolism, Molecular Sequence Data, Nucleic Acid, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Rabbits, Restriction Mapping, Reticulocytes/metabolism, RNA, RNA Precursors/chemistry/metabolism, Sequence Homology, Southern, Steggles A W, Transcription
Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).
Tags: *Gene Expression Regulation, 1998, Animals, Bile Acids and Salts/genetics, Binding Sites/genetics, Biochemical and biophysical research communications, Carcinoma, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Complementary/analysis, Cultured, Department of Integrative Medical Sciences, DNA, DNA-Binding Proteins/metabolism/*physiology, Electrophoresis, Enzyme Activation/genetics, Foti D, Genetic, Hepatocellular, Humans, Kruppel-Like Transcription Factors, Liver/enzymology, NEOMED College of Medicine, Podophyllin/analogs & derivatives/metabolism, Podophyllotoxin/analogs & derivatives, Polyacrylamide Gel, Promoter Regions, Protein Binding/genetics, Rats, Stroup D, Transcription Factors/metabolism/*physiology, Tumor Cells
The opposing effects of retinoic acid and phorbol esters converge to a common response element in the promoter of the rat cholesterol 7 alpha-hydroxylase gene (CYP7A).
Tags: *Promoter Regions, 1996, Animals, Base Sequence, Biochemical and biophysical research communications, Cell Line, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Crestani M, Department of Integrative Medical Sciences, DNA Primers, Galli G, Genetic, Molecular Sequence Data, Mutagenesis, NEOMED College of Medicine, Rats, Sadeghpour A, Signal Transduction, Stroup D, Tetradecanoylphorbol Acetate/*pharmacology, Tretinoin/*pharmacology
The isolation and characterization of the human cytochrome b5 gene.
Tags: 1995, Animals, Base Sequence, Biochemical and biophysical research communications, Cattle, Cell Line, Cloning, Cosmids, Cultured, Cytochromes b5/biosynthesis/*genetics, DNA Primers, DNA/genetics/isolation & purification, Gene Library, Genetic, Giordano S J, Hominidae/*genetics, Humans, Introns, Li X R, Luciferases/biosynthesis, Messenger/analysis/biosynthesis, Molecular, Molecular Sequence Data, Polymerase Chain Reaction, Promoter Regions, Rabbits, RNA, Steggles A W, Transfection, Tumor Cells, Yoo M
Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells.
Tags: 1994, Animals, Bile Acids and Salts/*pharmacology, Biochemical and biophysical research communications, Cells, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, Crestani M, Cultured, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Gene Expression Regulation, Genetic, Genetic/genetics, Humans, Karam W G, Luciferases/biosynthesis/genetics, Messenger/*biosynthesis, NEOMED College of Medicine, Promoter Regions, Rats, Recombinant Fusion Proteins/biosynthesis, RNA, Steroids/*pharmacology, Thyroid Hormones/*pharmacology, Transcription, Transfection
Promoter activity and regulation of the CYP4F2 leukotriene B(4) omega-hydroxylase gene by peroxisomal proliferators and retinoic acid in HepG2 cells.
Tags: *Gene Expression Regulation, *Promoter Regions, 2000, Amino Acid Sequence, Archives of biochemistry and biophysics, Base Sequence, Cell Line, Chen L, Cloning, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 4, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, DNA, DNA Footprinting, Enzymologic, Exons, Genes, Genetic, Genetic/drug effects, Hardwick J P, Humans, Introns, Leukotriene B4/metabolism, Mixed Function Oxygenases/metabolism, Models, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Peroxisome Proliferators/*metabolism, Receptors, Reporter, Retinoic Acid Receptor alpha, Retinoic Acid/metabolism, Sequence Analysis, Transcription, Transcription Factors/metabolism, Transfection, Tretinoin/*metabolism, Zhang X
A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.
Tags: 2007, Allen Kristi L, Apoptosis Regulatory Proteins/metabolism, Apoptosis/*drug effects, Awad Keytam S, bcl-2-Associated X Protein/metabolism, Caspase 3/metabolism, Caspase 9/metabolism, Cultured/drug effects, DeLucia Angelo L, Department of Integrative Medical Sciences, Enzyme Activation/drug effects, Female, Genetic, Humans, Luciferases, Lynch William P, Masoprocol/*analogs & derivatives/therapeutic use, Molecular carcinogenesis, NEOMED College of Medicine, Oncogene Proteins, Plants/chemistry, Proto-Oncogene Proteins/metabolism, Repressor Proteins/*metabolism, Transcription, Tschantz Deidra R, Tumor Cells, Tumor Suppressor Protein p53/genetics/*metabolism, Uterine Cervical Neoplasms/*drug therapy/metabolism/pathology, Viral/*metabolism
All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.
Tags: 2014, Animals, Axe David, Basic Helix-Loop-Helix Transcription Factors/genetics, Blood Glucose/analysis, Chiang John Y L, Cook Aaron, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Fatty Liver/*drug therapy/metabolism, Gene Expression Regulation, Genetic, Hardwick James P, Hepatology (Baltimore, Md.), Inbred C57BL, Kim Chun-Ki, Kim Seong-Chul, Lee Mikang, Lee Yoon-Kwang, Li Tiangang, Lipid Metabolism, Liver/metabolism, Male, Mice, Moore David D, NEOMED College of Medicine, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease, PPAR gamma/*genetics, Receptors, Repressor Proteins/genetics, Retinoic Acid Receptor alpha, Retinoic Acid/physiology, Smallwood Nicole, Transcription, Tretinoin/pharmacology/*therapeutic use
Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells.
Tags: 2006, Bile Acids and Salts/*metabolism, Cells, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Cultured, Cytokines/*metabolism, Department of Integrative Medical Sciences, Gene Expression Regulation, Genetic, Hepatocytes/*cytology/drug effects, Hepatology (Baltimore, Md.), Humans, Immunoblotting, In Vitro Techniques, Interleukin-1/pharmacology, Jahan Asmeen, Li Tiangang, Messenger/analysis, NEOMED College of Medicine, Probability, Proto-Oncogene Proteins c-jun/*metabolism, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sensitivity and Specificity, Signal Transduction/genetics, Transcription