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Text
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URL Address
<a href="http://doi.org/10.1093/jac/dkm119" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/jac/dkm119</a>
Pages
112–120
Issue
1
Volume
60
Dublin Core
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Title
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Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.
Publisher
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The Journal of antimicrobial chemotherapy
Date
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2007
2007-07
Subject
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80 and over; Adolescent; Adult; Aged; Anti-Bacterial Agents/*administration & dosage/adverse effects/therapeutic use; Bacterial/*drug therapy/microbiology; Community-Acquired Infections/*drug therapy/microbiology; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones/*administration & dosage/adverse effects/therapeutic use; Gemifloxacin; Humans; Male; Middle Aged; Naphthyridines/*administration & dosage/adverse effects/therapeutic use; Pneumococcal/drug therapy/microbiology; Pneumonia; Streptococcus pneumoniae/isolation & purification; Treatment Outcome
Creator
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File Thomas M Jr; Mandell Lionel A; Tillotson Glenn; Kostov Kosta; Georgiev Ognian
Description
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OBJECTIVES: Short-course therapy has been advocated for the treatment of community-acquired pneumonia (CAP). We compared the efficacy and safety of 5 and 7 day courses of gemifloxacin for outpatient treatment of mild-moderate CAP. PATIENTS AND METHODS: In a multicentre, double-blind, parallel group study, patients were randomized to receive 320 mg of oral gemifloxacin once daily for 5 or 7 days. Over 95% of all patients in each cohort had a Fine score of
Identifier
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<a href="http://doi.org/10.1093/jac/dkm119" target="_blank" rel="noreferrer noopener">10.1093/jac/dkm119</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2007
80 and over
Adolescent
Adult
Aged
Anti-Bacterial Agents/*administration & dosage/adverse effects/therapeutic use
Bacterial/*drug therapy/microbiology
Community-Acquired Infections/*drug therapy/microbiology
Department of Internal Medicine
Double-Blind Method
Drug Administration Schedule
Female
File Thomas M Jr
Fluoroquinolones/*administration & dosage/adverse effects/therapeutic use
Gemifloxacin
Georgiev Ognian
Humans
Kostov Kosta
Male
Mandell Lionel A
Middle Aged
Naphthyridines/*administration & dosage/adverse effects/therapeutic use
NEOMED College of Medicine
Pneumococcal/drug therapy/microbiology
Pneumonia
Streptococcus pneumoniae/isolation & purification
The Journal of antimicrobial chemotherapy
Tillotson Glenn
Treatment Outcome