1790: WARFARIN TRAUMA PATIENTS: COMPARING PROTHROMBIN COMPLEX CONCENTRATE TO VITAMIN K/FRESH FROZEN PLASMA.
WARFARIN; VITAMIN K; GLASGOW Coma Scale; INTERNATIONAL normalized ratio; PROTHROMBIN
B Learning Objectives: b There is scant data comparing Prothrombin Complex Concentrate (PCC) to Vitamin K/Fresh Frozen Plasma (FFP) in trauma patients. Patients that received PCC (PCC group) were compared to those who received Vitamin K/FFP (FFP group). [Extracted from the article]
Huang Gregory; Hileman Barbara; Chance Elisha; Gianetti Emily; Steiner Dena; Marchand Tiffany
Critical Care Medicine
2019
2019-01-02
Journal Article
<a href="http://doi.org/10.1097/01.ccm.0000552528.13105.55" target="_blank" rel="noreferrer noopener">10.1097/01.ccm.0000552528.13105.55</a>
Altered Mental Status In Older Patients In The Emergency Department
agitation-sedation scale; cognitive impairment; Coma; confusion assessment method; critically-ill; Delirium; diagnosis; elderly; Emergency department; epidemiology; Geriatrics & Gerontology; glasgow coma scale; hospitalized-patients; intensive-care unit; length-of-stay; management; multicomponent geriatric intervention; patients; risk-factors; Stupor
Altered mental status is a common chief compliant among older patients in the emergency department (ED). Acute changes in mental status are more concerning and are usually secondary to delirium, stupor, and coma. Although stupor and coma are easily identifiable, the clinical presentation of delirium can be subtle and is often missed without actively screening for it. For patients with acute changes in mental status the ED evaluation should focus on searching for the underlying etiology. Infection is one of the most common precipitants of delirium, but multiple causes may exist concurrently.
Han J H; Wilber S T
Clinics in Geriatric Medicine
2013
2013-02
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/j.cger.2012.09.005" target="_blank" rel="noreferrer noopener">10.1016/j.cger.2012.09.005</a>
Interactive Relationship Between Parent and Child Event Appraisals and Child PTSD Symptoms After an Injury.
Female; Male; Child; Glasgow Coma Scale; Self Report; Parents; Human; Questionnaires; Cross Sectional Studies; Descriptive Statistics; Scales; One-Way Analysis of Variance; Regression; T-Tests; Emergency Service; Stress Disorders; DSM; Severity of Injury; Post-Traumatic – Symptoms – In Infancy and Childhood; Trauma – In Infancy and Childhood
Morris Adam; Lee Timothy; Delahanty Douglas
Psychological Trauma: Theory, Research, Practice & Policy
2013
2013-11
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1037/a0029894" target="_blank" rel="noreferrer noopener">10.1037/a0029894</a>
Raising concerns about the Sepsis-3 definitions.
*Data Accuracy; *Infections; *Organ dysfunction; *Sepsis; *Septic shock; *Severity of Illness Index; Arterial Pressure; Consensus; Glasgow Coma Scale; Humans; Infection; Organ Dysfunction Scores; Publishing; Sensitivity and Specificity; Sepsis; Sepsis/*classification/mortality; Validation Studies
The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.
Sartelli Massimo; Kluger Yoram; Ansaloni Luca; Hardcastle Timothy C; Rello Jordi; Watkins Richard R; Bassetti Matteo; Giamarellou Eleni; Coccolini Federico; Abu-Zidan Fikri M; Adesunkanmi Abdulrashid K; Augustin Goran; Baiocchi Gian L; Bala Miklosh; Baraket Oussema; Beltran Marcelo A; Jusoh Asri Che; Demetrashvili Zaza; De Simone Belinda; de Souza Hamilton P; Cui Yunfeng; Davies R Justin; Dhingra Sameer; Diaz Jose J; Di Saverio Salomone; Dogjani Agron; Elmangory Mutasim M; Enani Mushira A; Ferrada Paula; Fraga Gustavo P; Frattima Sabrina; Ghnnam Wagih; Gomes Carlos A; Kanj Souha S; Karamarkovic Aleksandar; Kenig Jakub; Khamis Faryal; Khokha Vladimir; Koike Kaoru; Kok Kenneth Y Y; Isik Arda; Labricciosa Francesco M; Latifi Rifat; Lee Jae G; Litvin Andrey; Machain Gustavo M; Manzano-Nunez Ramiro; Major Piotr; Marwah Sanjay; McFarlane Michael; Memish Ziad A; Mesina Cristian; Moore Ernest E; Moore Frederick A; Naidoo Noel; Negoi Ionut; Ofori-Asenso Richard; Olaoye Iyiade; Ordonez Carlos A; Ouadii Mouaqit; Paolillo Ciro; Picetti Edoardo; Pintar Tadeja; Ponce-de-Leon Alfredo; Pupelis Guntars; Reis Tarcisio; Sakakushev Boris; Kafil Hossein Samadi; Sato Norio; Shah Jay N; Siribumrungwong Boonying; Talving Peep; Trana Cristian; Ulrych Jan; Yuan Kuo-Ching; Catena Fausto
World journal of emergency surgery : WJES
2018
1905-07
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1186/s13017-018-0165-6" target="_blank" rel="noreferrer noopener">10.1186/s13017-018-0165-6</a>
Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?
*Platelet Aggregation Inhibitors; Adult; Aged; Antiplatelet therapy; Aspirin/therapeutic use; Clopidogrel; Female; Glasgow Coma Scale; Hematoma; Humans; Intracranial hemorrhage; Intracranial Hemorrhage; Middle Aged; Platelet transfusion; Platelet Transfusion/*methods; Retrospective Studies; Risk Factors; Subdural/etiology/*prevention & control; Ticlopidine/analogs & derivatives/therapeutic use; Time Factors; Traumatic brain injury; Traumatic/complications/*therapy
Reversal of antiplatelet therapy with platelet transfusion in traumatic intracranial hemorrhage remains controversial. Several studies have examined this topic but few have investigated whether the timing of transfusion affects outcomes. Patients admitted to a level 1 trauma center from 1/1/14 to 3/31/16 with traumatic intracranial hemorrhage taking pre-injury antiplatelet therapy were retrospectively analyzed. Patients on concurrent pre-injury anticoagulant therapy were excluded. Per institutional guideline, patients on pre-injury clopidogrel received 2 doses of platelets while patients on pre-injury aspirin received 1 dose of platelets. Patients with worsening hemorrhage defined by an increase in the Rotterdam score on follow up CT were compared to those without worsening. Mortality, need for neurosurgical intervention, and timing of platelet transfusion were analyzed. A total of 243 patients were included with 23 (9.5%) having worsening hemorrhage. Patients with worsening hematoma had higher injury severity score, head abbreviated injury scale, incidence of subdural hematoma, mortality, and lower Glasgow coma scale. There was no significant difference in the number of minutes to platelet transfusion between groups. After logistic regression analysis the presence of subdural hematoma and lower admission Glasgow coma scale were predictors of worsening hematoma, while there remained no significant difference in minutes to platelet transfusion. The timing of platelet transfusion did not have any impact on rates of worsening hematoma for patients with traumatic intracranial hemorrhage on pre-injury antiplatelet therapy. Potential risk factors for worsening hematoma in this group are the presence of subdural hematoma and lower admission Glasgow coma scale.
Pandya Urmil; Malik Alexander; Messina Michael; Albeiruti Abdul-Rahman; Spalding Chance
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2018
2018-04
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1016/j.jocn.2018.01.073" target="_blank" rel="noreferrer noopener">10.1016/j.jocn.2018.01.073</a>