1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.molbrainres.2005.02.030" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.molbrainres.2005.02.030</a>
Pages
143–151
Issue
1
Volume
137
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
APeg3, a novel paternally expressed gene 3 antisense RNA transcript specifically expressed in vasopressinergic magnocellular neurons in the rat supraoptic nucleus.
Publisher
An entity responsible for making the resource available
Brain research. Molecular brain research
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005-06
Subject
The topic of the resource
3' Untranslated Regions/genetics; Amino Acid; Animals; Antisense/*genetics/isolation & purification/*metabolism; Conserved Sequence/genetics; DNA-Binding Proteins/genetics/*metabolism; Gene Expression Regulation/*genetics; Genetic/genetics; Genomic Imprinting/genetics; Hypothalamo-Hypophyseal System/cytology/metabolism; Kruppel-Like Transcription Factors; Male; Messenger/genetics/metabolism; Molecular Sequence Data; Neurons/*metabolism; Nucleic Acid; Protein Kinases/genetics/*metabolism; Rats; RNA; Sequence Homology; Sprague-Dawley; Supraoptic Nucleus/cytology/*metabolism; Transcription; Transcription Factors/genetics/*metabolism; Vasopressins/*metabolism; Water-Electrolyte Balance/genetics
Creator
An entity primarily responsible for making the resource
Glasgow Eric; Ryu Seung-Lim; Yamashita Mitsuo; Zhang Bing-Jun; Mutsuga Noriko; Gainer Harold
Description
An account of the resource
Vasopressin (VP) and oxytocin (OT) play critical roles in the regulation of salt and water balance, lactation, and various behaviors and are expressed at very high levels in specific magnocellular neurons (MCNs) in the hypothalamo-neurohypophysial system (HNS). In addition to the cell-specific expression of the VP and OT genes in these cells, there are other transcripts that are preferentially expressed in the VP or OT MCNs. One such gene, paternally expressed gene 3 (Peg3), is an imprinted gene expressed exclusively from the paternal allele that encodes a Kruppel-type zinc finger-containing protein involved in maternal behavior and is abundantly expressed in the VP-MCNs. We report here the robust expression in the VP-MCNs of an RNA, which we designate APeg3 that is transcribed in the antisense direction to the 3' untranslated region of the Peg3 gene. The APeg3 mRNA is about 1 kb in size, and the full-length sequence of APeg3, as determined by 5' and 3' RACE, contains an open reading frame that predicts a protein of 93 amino acids and is predominantly expressed in VP-MCNs. Both Peg3 and APeg3 gene expression in the VP-MCNs increase during systemic hyperosmolality in vivo, demonstrating that both of these genes are osmoregulated.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.molbrainres.2005.02.030" target="_blank" rel="noreferrer noopener">10.1016/j.molbrainres.2005.02.030</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2005
3' Untranslated Regions/genetics
Amino Acid
Animals
Antisense/*genetics/isolation & purification/*metabolism
Brain research. Molecular brain research
Conserved Sequence/genetics
DNA-Binding Proteins/genetics/*metabolism
Gainer Harold
Gene Expression Regulation/*genetics
Genetic/genetics
Genomic Imprinting/genetics
Glasgow Eric
Hypothalamo-Hypophyseal System/cytology/metabolism
Kruppel-Like Transcription Factors
Male
Messenger/genetics/metabolism
Molecular Sequence Data
Mutsuga Noriko
Neurons/*metabolism
Nucleic Acid
Protein Kinases/genetics/*metabolism
Rats
RNA
Ryu Seung-Lim
Sequence Homology
Sprague-Dawley
Supraoptic Nucleus/cytology/*metabolism
Transcription
Transcription Factors/genetics/*metabolism
Vasopressins/*metabolism
Water-Electrolyte Balance/genetics
Yamashita Mitsuo
Zhang Bing-Jun
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s1567-133x(02)00064-9" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s1567-133x(02)00064-9</a>
Pages
105–108
Issue
1
Volume
3
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Expression of isotocin-neurophysin mRNA in developing zebrafish.
Publisher
An entity responsible for making the resource available
Gene expression patterns : GEP
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-03
Subject
The topic of the resource
Amino Acid Sequence; Animals; Messenger/*metabolism; Molecular Sequence Data; Neurophysins/biosynthesis/*genetics; Oxytocin/*analogs & derivatives/biosynthesis/*genetics; Phylogeny; RNA; Zebrafish/*embryology
Creator
An entity primarily responsible for making the resource
Unger Jennifer L; Glasgow Eric
Description
An account of the resource
Neurohypophysial peptides are important regulators of homeostasis, reproduction and behavior. We have sequenced a zebrafish cDNA representing isotocin-neurophysin (IT-NP) mRNA. The developmental expression pattern of zebrafish IT-NP mRNA was determined by whole-mount in situ hybridization histochemistry. At 32 h post fertilization (hpf) no IT-NP mRNA is detected. However, by 36 hpf, staining for IT-NP mRNA is detected in a tight bilateral cluster of cells located in the anterior hypothalamus. The IT-NP mRNA expression pattern remains remarkably stable throughout further development at least until 120 hpf.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s1567-133x(02)00064-9" target="_blank" rel="noreferrer noopener">10.1016/s1567-133x(02)00064-9</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2003
Amino Acid Sequence
Animals
Gene expression patterns : GEP
Glasgow Eric
Messenger/*metabolism
Molecular Sequence Data
Neurophysins/biosynthesis/*genetics
Oxytocin/*analogs & derivatives/biosynthesis/*genetics
Phylogeny
RNA
Unger Jennifer L
Zebrafish/*embryology