Browse Items (20 total)
- Tags: Glaucoma
Absence of cytochrome P450-1b1 increases susceptibility of pressure-induced axonopathy in the murine retinal projection.
Tags: 2021, Amirmokhtari N, April 2021 List, axonal transport disruption, Bouhenni RA, Department of Pharmaceutical Sciences, Dewan SS, Foresi BD, Frontiers In Cell And Developmental Biology, Glaucoma, journalArticle, microbead occlusion model, NEOMED College of Graduate Studies Student, NEOMED College of Pharmacy, NEOMED Student Publications, nodes of Ranvier, Retinal ganglion cell, Smith MA
Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta.
Tags: 2020, Alzheimer's disease, amyloid-beta, CD36, Cluster of differentiation 36, Crish SD, Dengler-Crish C M, Glaucoma, Inflammation, journalArticle, NEOMED College of Graduate Studies Student, NEOMED Student Publications, Neurobiology of disease, October 2020 List, retina, Simons ES, Smith M A, superior colliculus
Tags: 2020, angiogenesis, calcium channel, Cornea, Department of Integrative Medical Sciences, diabetic retinopathy, Experimental eye research, Glaucoma, Guarino BD, journalArticle, Lens, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Osmolarity, Paruchuri S, retina, September 2020 List, Thodeti CK, TRPV4
MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.
Tags: 2020, Coughlin Lucy, Department of Pharmaceutical Sciences, Glaucoma, Harun-Or-Rashid Mohammad, Inman Denise M, Jassim Assraa Hassan, journalArticle, June 2020 Update II, Metabolism, Monocarboxylate transporter, NEOMED College of Pharmacy Student, NEOMED Student Publications, Neurobiology of disease, Ocular Hypertension, Pappenhagen Nathaniel, Retinal ganglion cell, Zubricky Ryan
Tags: 2019, corticosteroid, Glaucoma, glaucoma surgery, intraocular pressure management, January 2020 Update, Journal Article, Kahook Malik Y, Kesav Natasha, NEOMED College of Medicine Student, NEOMED Student Publications, Ocular Hypertension, Palestine Alan G, Pantcheva Mina B, Survey of Ophthalmology, uveitis
Decreased Energy Capacity And Increased Autophagic Activity In Optic Nerve Axons With Defective Anterograde Transport
Tags: 2015, anterograde transport, Autophagy, Cholera, cholera-toxin, Crish S D, degeneration, Department of Pharmaceutical Sciences, dying back process, endoplasmic-reticulum, Glaucoma, Inman D M, Investigative ophthalmology & visual science, Journal Article or Conference Abstract Publication, Kleesattel D, Microscopy, Mitochondria, mitophagy, Mouse model, NEOMED College of Pharmacy, Ophthalmology, optic neuropathy, Stress, toxin-B
Tags: 2014, alzheimers-disease, amyloid-beta, aqueous-humor, Biochemistry & Molecular Biology, Biometals, Braymer J J, Crish S D, Deb A, Dengler-Crish C M, Department of Pharmaceutical Sciences, DeToma A S, ganglion-cell degeneration, gene-expression, Glaucoma, ICP-MS, iron, Lim M H, Microarray Analysis, NEOMED College of Pharmacy, Neurodegeneration, Penner-Hahn J E, retina, superior colliculus, synapse, Van der Schyf C J
Tags: 2013, activated protein-kinase, alzheimers-disease brain, amyotrophic-lateral-sclerosis, Axonopathy, Calkins D J, Crish S D, Dapper J D, Death, Department of Pharmaceutical Sciences, experimental glaucoma, ganglion-cell neurons, Glaucoma, Heat shock protein, Journal Article or Conference Abstract Publication, Mouse model, NEOMED College of Pharmacy, Neurobiology of disease, Neurodegeneration, Neurosciences & Neurology, Ocular Hypertension, p38 MAPK, Pang I H, rat retina, Retinal ganglion cell, Up-Regulation
Suppression of transforming growth factor-beta effects in rabbit subconjunctival fibroblasts by activin receptor-like kinase 5 inhibitor
Tags: 2010, anti-scarring agent, Biochemistry & Molecular Biology, choroidal, Dunmire J J, extracellular-matrix, Fibrosis, Geldenhuys W J, Glaucoma, Hewit M, identification, in-vivo, Journal Article, mitomycin-c, Molecular Vision, Nakamura H, Neovascularization, Ophthalmology, Sapitro J, Scott S E, Surgery, Sutariya V, tgf-beta, Yue Byjt
Tags: 2015, Aging, axonal-transport, axoplasmic-transport, Crish S D, Cytokines, Denger-Crish C M, Department of Pharmaceutical Sciences, fibroblast-growth-factor, gene-expression, Glaucoma, Immunology, Inflammation, Inman D M, Intraocular Pressure, Journal Article, Journal of neuroinflammation, necrosis-factor-alpha, NEOMED College of Pharmacy, Neurodegeneration, Neurosciences & Neurology, Ocular Hypertension, optic-nerve head, retinal ganglion-cells, Smith M A, TNF-alpha, Wilson G N
Tags: 2009, acid, aqueous-humor, bimatoprost, clinical-trial, cost-effectiveness, Edward D P, elevated intraocular-pressure, Expert Opinion on Pharmacotherapy, fixed combination, free, Glaucoma, human eyes, Intraocular Pressure, Journal Article, Ocular Hypertension, open-angle glaucoma, Patil A J, Pharmacology & Pharmacy, prostaglandin, prostaglandin-ethanolamides, prostamide, prostamides, Vajaranant T S
Higher Reliance on Glycolysis Limits Glycolytic Responsiveness in Degenerating Glaucomatous Optic Nerve.
Tags: 2019, Chen Yeong-Renn, Coughlin Lucy, DBA/2J, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Fluorocitrate, Glaucoma, Harun-Or-Rashid Mohammad, Inman Denise M, Jassim Assraa Hassan, Kang Patrick T, Mitochondria, Molecular neurobiology, NEOMED College of Medicine, NEOMED College of Pharmacy, optic nerve, Seahorse analyzer
Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma.
Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma.
Tags: 2014, Axonal Transport, Axonopathy, Crish Samuel D, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Frontiers in neuroscience, Glaucoma, Inman Denise M, NEOMED College of Medicine, NEOMED College of Pharmacy, Neurodegeneration, ocular, optic nerve, Smith Matthew A, superior colliculi, vision disorders, Wilson Gina N, Young Jesse W
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Tags: 2018, AMP-activated protein kinase, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cells – Drug Effects, Cells – Pathology, Department of Pharmaceutical Sciences, Diet, Disease Models, Eye Proteins/genetics, Female, G-Protein-Coupled – Metabolism, G-Protein-Coupled/*metabolism, Glaucoma, Glaucoma – Complications, Glaucoma – Pathology, Glaucoma/*complications/pathology, Harun-Or-Rashid Mohammad, Impact of Events Scale, Inbred DBA, Inflammation – Etiology, Inflammation – Prevention and Control, Inflammation hydroxycarboxylic acid receptor, Inflammation/*etiology/*prevention & control, Inman Denise M, Journal of neuroinflammation, Ketogenic diet, Ketogenic/methods, Male, Membrane Glycoproteins, Membrane Glycoproteins/genetics, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia/drug effects/pathology, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Neuroprotection/drug effects/*physiology, NLR Family, Optic Nerve – Pathology, Optic Nerve/pathology, Phosphotransferases – Metabolism, Proteins, Pyrin Domain-Containing 3 Protein/genetics/metabolism, Receptors, Retina – Drug Effects, Retina – Pathology, Retinal Ganglion Cells/drug effects/*pathology, Transgenic
Tags: 1996, Adult, Aged, Angle-Closure/diagnosis/therapy, Corneal Ulcer/diagnosis/therapy, Eye Diseases/*diagnosis/*therapy, Female, Glaucoma, Humans, Iritis/diagnosis/therapy, Male, Postgraduate medicine, Referral and Consultation, Retinal Artery Occlusion/diagnosis/therapy, Retinal Detachment/diagnosis/therapy, Weinstock F J, Weinstock M B
Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma.
Tags: *Astrocyte, *Axonopathy, *Glaucoma, *Gliosis, *neurodegeneration, *Retinal ganglion cell, 2016, Animal, Animals, Astrocytes/*pathology, Axons/pathology, Calkins David J, Cooper Melissa L, Crish Samuel D, Department of Pharmaceutical Sciences, Disease Models, Experimental eye research, Glaucoma, Horner Philip J, Imaging, Inbred DBA, Inman Denise M, Mice, NEOMED College of Pharmacy, Nerve Degeneration/etiology/*pathology, Open-Angle/*pathology, Optic Nerve Diseases/etiology/*pathology, Optic Nerve/*pathology, Photomicrography, Retinal Ganglion Cells/*pathology, Three-Dimensional, Time Factors