Browse Items (9 total)
- Tags: Glucose/metabolism
Cholesterol 7alpha-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Tags: *bile acids and salt/metabolism, *cholesterol/diet, *Lipids, *Liver, 2016, Animal, Animals, Bile Acids and Salts/genetics/metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/metabolism, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Diet, Disease Models, Exhalation/genetics, Ferrell Jessica M, Glucose/metabolism, High-Fat, Homeostasis, Humans, Journal of lipid research, Li Feng, Lipid Metabolism/genetics, Liver/enzymology/pathology, Metabolic Diseases/*genetics/metabolism, Mice, NEOMED College of Medicine
The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.
Tags: 2015, Animals, Bile Acids and Salts/metabolism, Cytoplasmic and Nuclear/biosynthesis/*genetics/metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus/*drug therapy/genetics/metabolism, Gene Expression Regulation/drug effects, Glucose/metabolism, Hepatocytes/drug effects, Humans, Insulin Resistance/genetics, Insulin/*metabolism, Journal of biomedical science, Lee Yoon-Kwang, Leptin/deficiency/genetics, Lipid Metabolism/drug effects, Messenger/genetics, Mice, Moore David D, NEOMED College of Medicine, Obese, Park Young Joo, PPAR gamma/*biosynthesis/genetics, Receptors, RNA, Thiazolidinediones/*administration & dosage, Tseng Hsiu-Ting
Tags: 2014, Animals, Bile Acids and Salts/biosynthesis/*metabolism/therapeutic use, Biological, Chiang John Y L, Circadian Rhythm/physiology, Department of Integrative Medical Sciences, G-Protein-Coupled/metabolism, Glucose/metabolism, Humans, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Metabolic Diseases/*drug therapy/*metabolism, Microbiota/physiology, MicroRNAs/metabolism, Models, NEOMED College of Medicine, Pharmacological reviews, Receptors, Signal Transduction/physiology
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis.
Tags: 2005, Animals, Annexin A5/metabolism, Anti-Bacterial Agents/metabolism, Apoptosis/*physiology, Biomarkers, Carlson Sara G, Caspase 12, Caspases/metabolism, CCAAT-Enhancer-Binding Proteins/metabolism, Cell Differentiation/*physiology, Cells, Chondrocytes/cytology/*physiology, Collagen Type II/metabolism, Cultured, Department of Anatomy & Neurobiology, DNA Fragmentation, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/metabolism, Gene Expression Regulation, Glucose/metabolism, Horton Walter E Jr, McBurney Denise, NEOMED College of Medicine, Proliferating Cell Nuclear Antigen/metabolism, Rats, Signal Transduction/*physiology, Thapsigargin/metabolism, The Journal of biological chemistry, Transcription Factor CHOP, Transcription Factors/metabolism, Tunicamycin/metabolism, Yang Ling
Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism.
Tags: *bile acid, *bile acid metabolism, *FXR, *Gene Expression Regulation, *GLP-1, *Lipid Metabolism, *liver metabolism, *Non-alcoholic Fatty Liver Disease, *Obesity, *TGR5, *type 2 diabetes, 2017, Animals, Bile Acids and Salts/*biosynthesis/genetics, Boehme Shannon, Chiang John Y L, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Dietary Fats, G-Protein-Coupled/genetics/*metabolism, Glucagon-Like Peptide 1/genetics/metabolism, Glucose/metabolism, Gonzalez Frank, Knockout, Krausz Kristopher W, Lipid Metabolism, Liu Hailiang, Liver/*metabolism, Mice, NEOMED College of Medicine, Obesity/genetics/*metabolism/pathology, Pathak Preeti, Receptors, The Journal of biological chemistry, Xie Cen
Tags: 2010, Absorption, Anderson Jody, Animals, Biological, Cell Line, Cholesterol/*metabolism, Class B/*genetics/metabolism, Coronary Disease/metabolism, Cytoplasmic and Nuclear/*metabolism, Department of Integrative Medical Sciences, Edwards Peter A, Glucose/metabolism, Gonzalez Frank J, Hepatocyte Nuclear Factor 4/metabolism, Homeostasis, Humans, Lipoproteins/metabolism, Liver/metabolism, Ma Huiyan, Mice, Models, NEOMED College of Medicine, Receptors, Scavenger Receptors, The Journal of biological chemistry, Willson Timothy M, Yin Liya, Zhang Yanqiao
Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE(-/-) mice.
Tags: 2017, Animals, Aorta/drug effects/metabolism, Apolipoproteins E/*metabolism, Atherosclerosis/*drug therapy/metabolism, Chavez Ronaldo J, Department of Integrative Medical Sciences, Diabetes Mellitus, Diabetic Angiopathies/drug therapy/metabolism, Experimental/chemically induced/drug therapy/metabolism, Ganguly Rituparna, Glucose/metabolism, Glycosylation/drug effects, Haney Rebecca, Hyperglycemia/*drug therapy/metabolism, Inbred C57BL, Knockout, Male, Mice, Myocytes, NEOMED College of Medicine, NEOMED Student Publications, Ohanyan Vahagn, Picolinic Acids/*pharmacology, Raman Priya, Sahu Soumyadip, Scientific reports, Shah Shivani, Smooth Muscle/drug effects, Streptozocin/*pharmacology, Thrombospondin 1/*metabolism, Type 1/chemically induced/*drug therapy/metabolism, Yalamanchili Siri
Tags: 2013, Animals, Bile Acids and Salts/*metabolism, Biochemical pharmacology, Cholesterol, Cytoplasmic and Nuclear/agonists/*metabolism, Fatty Liver/drug therapy/immunology/*metabolism, FXR, G-Protein-Coupled/agonists/*metabolism, Glucose/metabolism, Humans, Inflammation, Jadhav Kavita, Li Yuanyuan, Lipid Metabolism/drug effects, Lipid Regulating Agents/chemistry/pharmacology/therapeutic use, Molecular Structure, Non-alcoholic Fatty Liver Disease, Receptors, TGR5, Triglyceride, Triglycerides/metabolism, Zhang Yanqiao
Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice.
Tags: *Lipid Metabolism, 2016, Adiposity, Animals, Carboxylesterase/*metabolism, Carboxylic Ester Hydrolases/genetics/*metabolism, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Diabetes Mellitus, Diet, Endoplasmic Reticulum Stress, Energy Metabolism, Experimental/enzymology, Gene Knockdown Techniques, Glucose Tolerance Test, Glucose/metabolism, Hepatocyte Nuclear Factor 4/*metabolism, Hepatology (Baltimore, Md.), High-Fat/adverse effects, Homeostasis, Humans, Inbred C57BL, Jadhav Kavita, Kasumov Takhar, Li Yuanyuan, Lipogenesis, Lipolysis, Liver/enzymology, Male, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*etiology/metabolism, Obesity/enzymology/etiology, Sterol Regulatory Element Binding Protein 1/metabolism, Xu Yang, Yin Liya, Zalzala Munaf, Zhang Yanqiao