Description
Conditioning stimulation applied to afferent fibers in stratum radiatum or stratum oriens of hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of excitatory postsynaptic potentials (EPSPs). PTD amounted to a
Subject
Afferent/drug effects; Animals; Electric Stimulation; Electrophysiology; Evoked Potentials/physiology; Glutamate/drug effects; Glutamates/pharmacology; Glutamic Acid; Hippocampus/drug effects/*physiology; In Vitro Techniques; Membrane Potentials/physiology; N-Methyl-D-Aspartate/antagonists & inhibitors; Neuronal Plasticity/drug effects/physiology; Neurons; Presynaptic/drug effects/*physiology; Pyramidal Cells/drug effects; Rats; Receptors; Synapses/drug effects/*physiology