1 40 2 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1039/c2fo30058c" target="_blank" rel="noreferrer noopener">http://doi.org/10.1039/c2fo30058c</a> Pages 795–809 Issue 8 Volume 3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The health benefits of blackcurrants. Publisher An entity responsible for making the resource available Food & function Date A point or period of time associated with an event in the lifecycle of the resource 2012 2012-08 Subject The topic of the resource *Health Promotion; *Ribes/chemistry; Anthocyanins/analysis; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Fatty Acids; Flavonoids/analysis; Fruit/chemistry; Humans; Phytogenic; Phytotherapy; Plant Extracts/adverse effects/pharmacokinetics/pharmacology; Unsaturated/analysis Creator An entity primarily responsible for making the resource Gopalan Ashwin; Reuben Sharon C; Ahmed Shamima; Darvesh Altaf S; Hohmann Judit; Bishayee Anupam Description An account of the resource The blackcurrant (Ribes nigrum L., Grossulariceae), a small, perennial shrub native to central Europe and northern Asia, is cultivated throughout the world, including the United States. In addition to its anecdotal use in traditional herbal medicine, modern laboratories have demonstrated the potent anti-inflammatory, antioxidant and antimicrobial effects of blackcurrant constituents on a myriad of disease states. The properties of the blackcurrants are conferred from its biochemical constituents, some of which include anthocyans (specifically delphinidin-3-O-glucoside, delphinidin-3-O-rutinoside, cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside), flavonols, phenolic acids and polyunsaturated fatty acids. A plethora of studies have been published with regards to its various therapeutic applications. This article attempts to summarize these studies, providing a general overview of the research in this field. Several studies focus on the therapeutic potential of blackcurrants with regards to hypertension and other cardiovascular-associated illnesses, neoplastic, neurodegenerative and ocular diseases, nephrolithiasis, and diabetic neuropathy. Safety concerns and future directions are also mentioned, suggesting the critical examination of the exact mechanism of action, specific radical-scavenging capabilities of the blackcurrants and the crucial need for well-designed clinical trials to ensure the successful use of blackcurrants in a clinical setting. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1039/c2fo30058c" target="_blank" rel="noreferrer noopener">10.1039/c2fo30058c</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). *Health Promotion *Ribes/chemistry 2012 Ahmed Shamima Anthocyanins/analysis Anti-Infective Agents Anti-Inflammatory Agents Antineoplastic Agents Antioxidants Bishayee Anupam Darvesh Altaf S Department of Pharmaceutical Sciences Fatty Acids Flavonoids/analysis Food & function Fruit/chemistry Gopalan Ashwin Hohmann Judit Humans NEOMED College of Pharmacy Phytogenic Phytotherapy Plant Extracts/adverse effects/pharmacokinetics/pharmacology Reuben Sharon C Unsaturated/analysis Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/mnfr.201100619" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/mnfr.201100619</a> Pages 14–29 Issue 1 Volume 56 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer. Publisher An entity responsible for making the resource available Molecular nutrition & food research Date A point or period of time associated with an event in the lifecycle of the resource 2012 2012-01 Subject The topic of the resource *Diet; Anticarcinogenic Agents/*chemistry/*pharmacology; Breast Neoplasms/*blood supply/*prevention & control; Female; Humans; Malus/chemistry; Neovascularization; Pathologic/metabolism/prevention & control Creator An entity primarily responsible for making the resource Reuben Sharon C; Gopalan Ashwin; Petit Danielle M; Bishayee Anupam Description An account of the resource Breast cancer is the leading cause of cancer-related deaths for women in the United States and the rest of the world. About 8% of women develop breast cancer during the course of their lives. Dietary habits are closely associated with both the risk and progression of breast cancer. Dietary agents have accumulated increasing importance with regards to the prevention and treatment of breast cancer. One such manner by which these compounds can target breast cancer development and progression is through interference with the angiogenic pathways. Angiogenesis is an intricate process that involves the development of new capillaries from previously existing blood vessels. Disruption of this pathway, therefore, provides a novel and effective avenue for therapeutic intervention of breast cancer. Various phytochemicals found in the diet kill breast cancer cells in vitro and prevent as well as suppress breast cancer progression in various preclinical animal models. This review examines the value of dietary phytoconstituents in the prevention and treatment of breast cancer through modulation of the intricate and complex process of angiogenesis. In addition, the potential benefits, challenges, and future directions of research on anti-angiogenic dietary phytochemicals in the prevention and intervention of breast cancer are also addressed. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/mnfr.201100619" target="_blank" rel="noreferrer noopener">10.1002/mnfr.201100619</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). *Diet 2012 Anticarcinogenic Agents/*chemistry/*pharmacology Bishayee Anupam Breast Neoplasms/*blood supply/*prevention & control Female Gopalan Ashwin Humans Malus/chemistry Molecular nutrition & food research Neovascularization Pathologic/metabolism/prevention & control Petit Danielle M Reuben Sharon C