Comparison of Sonography and Scintigraphy in the Evaluation of Gallbladder Functional Studies With Cholecystokinin
pain; Acoustics; ultrasonography; Radiology; disease; Nuclear Medicine & Medical Imaging; sonography; contraction; gallstones; cholecystokinin; cholescintigraphy; chronic acalculous cholecystitis; ejection fraction; gallbladder ejection fraction; infusion; scintigraphy
Objective. Both sonography and scintigraphy have been used to evaluate gallbladder function with the use of sincalide (cholecystokinin [CCK]). However, the reported ejection fractions (EFs) for the two modalities are not the same. The techniques measure slightly different parameters. This study directly compared both techniques performed simultaneously on the same participants. Methods. Twenty healthy volunteers were evaluated with sonography and scintigraphy to estimate the gallbladder EF simultaneously. The gallbladder EF was calculated at 5-minute intervals for 1 hour. Results. The mean El's +/- SD were 66.3% +/- 20% and 49% +/- 29% for sonography and scintigraphy, respectively. The mean times to the peak EF were 38 12 and 33 9 minutes for sonography and scintigraphy. An average time of 34 minutes was noted after radiopharmaceutical injection before CCK administration for the scintigraphic studies. The earliest time to the peak EF for sonography was 15 minutes, and the latest time to the peak EF was 60 minutes (mode, 40 minutes); for scintigraphy, the earliest and latest times were 15 and 50 minutes (mode, 30 minutes), respectively. One participant could not be evaluated secondary to nonfilling of the gallbladder on scintigraphy. There was wider variability of the gallbladder EF with scintigraphy than sonography. Conclusions. Scintigraphy estimated a lower EF than sonography, had wider EF variability than sonography, and required additional time (>30 minutes more) to complete the study. Scintigraphy could not be performed in 5% of the participants because of nonfilling of the gallbladder The use of sonography to estimate the gallbladder EF is less time-consuming and less costly. With these techniques, the range of normal gallbladder El's should be adjusted for the technique used.
Barr R G; Kido T; Grajo J R
Journal of Ultrasound in Medicine
2009
2009-09
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.7863/jum.2009.28.9.1143" target="_blank" rel="noreferrer noopener">10.7863/jum.2009.28.9.1143</a>
Strain Elastography For Prediction Of Breast Cancer Tumor Grades
Acoustics; agreement; breast; breast cancer; breast ultrasound; ductal carcinoma; elasticity; elastography; experience; grade; histologic grade; lesions; Nuclear Medicine & Medical Imaging; prognostic factors; Radiology; sonoelastography; sonography; strain; tumor; Ultrasound
Objectives-The purpose of this study was to determine whether the elasticity imaging/B-mode ratio on strain elastography can predict breast cancer tumor grades. Methods-A retrospective review of patients with breast lesions who underwent strain elastography and had a diagnosis of breast cancer by image-guided or surgical biopsy was performed. The axis of the maximum elastographic dimension was compared to the B-mode dimension to form an elasticity imaging/B-mode ratio. Lesions were categorized according to their pathologic type, including atypical ductal hyperplasia (ADH), mucinous or colloid cancer, ductal carcinoma in situ (DCIS), grade I invasive ductal carcinoma (MC), grade II IDC, grade III DC, invasive lobular carcinoma (ILC), and lymphoma. The mean elasticity imaging/B-mode ratio of each tumor type was calculated. The elasticity imaging/B-mode ratio of the tumor was compared to the tumor type by Kruskal-Wallis and Tukey-Kramer tests (lymphoma and ADH excluded because of small numbers). Results-Tumor grades included lymphoma (n = 3),.ADH (n = 2), mucinous cancer (n = 11), DCIS (n = 19), DC (grades I III; n = 200), and ILC (n = 31). The mean elasticity imaging/B-mode ratio varied with increasing tumor grade. Tumor grades could not have been selected at random from one population (P < .0001, chi(2) test). Invasive lobular carcinoma and grade III DC were statistically different from mucinous or colloid cancer, DCIS, and grade land II IDC. Conclusions-The elasticity imaging/B-mode ratio on strain elastography is related to the tumor grade.
Grajo J R; Barr R G
Journal of Ultrasound in Medicine
2014
2014-01
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.7863/ultra.33.1.129" target="_blank" rel="noreferrer noopener">10.7863/ultra.33.1.129</a>