HOSPITAL-BASED PULMONARY PATHOGENS - EVOLVING BACTERIAL-RESISTANCE
antimicrobial resistance; ceftazidime; drug-resistance; gram-negative bacteria; Immunology; Infectious Diseases; nosocomial infections; pneumococcal bacteremia; resistance; spectrum beta-lactamases; staphylococcus-aureus infections; Streptococcus pneumoniae; therapy
Tan J S; File T M
Infectious Diseases in Clinical Practice
1995
1995-09
Journal Article
n/a
MITRAL-VALVE ENDOCARDITIS CAUSED BY A SERUM-RESISTANT STRAIN OF ESCHERICHIA-COLI
beta-lactam antibiotics; ceftriaxone; diagnosis; Drug therapy; echocardiographic demonstration; gram-negative bacteria; hospitals; Immunology; Infectious Diseases; infective endocarditis; Microbiology; pulmonary valve; spectrum
Endocarditis due to Escherichia coli is rare. The case of a 79-year-old woman with E. coli bacteremia and multiple hemorrhagic cerebral infarcts is reported. A two-dimensional echocardiogram showed no evidence of a vegetation. While she was receiving antimicrobial therapy, bacteremia, hematuria, conjunctival petechiae, and a mitral regurgitant murmur occurred. The patient died, and at autopsy a large (2.2 x 2.0 x 0.7 cm) necrotic vegetation on the anterior leaflet of the mitral valve and several hemorrhagic infarcts of the brain were noted. An in vitro study with use of pooled human serum was performed and demonstrated that the patient's infecting strain of E. coli was serum resistant, in contrast to a serum-sensitive control strain of E. coli that was isolated from the cultures of blood from a patient with pyelonephritis. Including our case, 19 well-described cases of E. coli endocarditis from 1945 to 1990 have been reported. E. coli can cause endocarditis of both sides of the heart. More cases of endocarditis of host valves than of prosthetic valves have been documented.
Watanakunakorn C; Kim J
Clinical Infectious Diseases
1992
1992-02
Journal Article
<a href="http://doi.org/10.1093/clinids/14.2.501" target="_blank" rel="noreferrer noopener">10.1093/clinids/14.2.501</a>
The Science of Selecting Antimicrobials for Community-Acquired Pneumonia (CAP)
Antibiotics; Human; Practice Guidelines; Drug Resistance; Pneumonia; Drug Therapy; Microbial; Combination; Microbial Culture and Sensitivity Tests; Antiinfective Agents; Streptococcus; Gram-Negative Bacteria; Antibiotics – Therapeutic Use; Community-Acquired Infections – Drug Therapy; Bacterial – Drug Therapy; Macrolide – Therapeutic Use; Quinolone – Therapeutic Use; Lactam – Therapeutic Use; Legionnaires' Disease – Drug Therapy
File T M
Journal of Managed Care Pharmacy
2009
2009-03-02
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.18553/jmcp.2009.15.s2.5" target="_blank" rel="noreferrer noopener">10.18553/jmcp.2009.15.s2.5</a>