1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1523/jneurosci.22-23-10449.2002" target="_blank" rel="noreferrer noopener">http://doi.org/10.1523/jneurosci.22-23-10449.2002</a> Pages 10449–10460 Issue 23 Volume 22 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Projection to the inferior colliculus from the basal nucleus of the amygdala. Publisher An entity responsible for making the resource available The Journal of neuroscience : the official journal of the Society for Neuroscience Date A point or period of time associated with an event in the lifecycle of the resource 2002 2002-12 Subject The topic of the resource Animals; Acoustic Stimulation/methods; Species Specificity; Action Potentials/physiology; Amygdala/*cytology/physiology; Dextrans; Rhodamines; Fluorescent Dyes; *Stilbamidines; Auditory Cortex/cytology; Auditory Pathways/*cytology/physiology; Axonal Transport/physiology; Brain Stem/cytology; Chiroptera/*anatomy & histology/physiology; Cholera Toxin/pharmacokinetics; Inferior Colliculi/*cytology/physiology; Neurons/cytology/physiology; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; Electrodes; Implanted Creator An entity primarily responsible for making the resource Marsh Robert A; Fuzessery Zoltan M; Grose Carol D; Wenstrup Jeffrey J Description An account of the resource This report describes a projection from the amygdala, a forebrain center mediating emotional expression, to the inferior colliculus (IC), the midbrain integration center of the ascending auditory system. In the IC of mustached bats (Pteronotus parnellii) and pallid bats (Antrozous pallidus), we placed deposits of retrograde tracers at physiologically defined sites and then searched for retrogradely labeled somata in the forebrain. Labeling was most sensitive in experiments using cholera toxin B-subunit as tracer. We consistently observed retrograde labeling in a single amygdalar subdivision, the magnocellular subdivision of the basal nucleus (Bmg). The Bmg is distinctive across mammals, containing the largest cells in the amygdala and the most intense acetylcholinesterase staining. Labeled amygdalar cells occurred ipsilateral and contralateral to IC deposits, but ipsilateral labeling was greater, averaging 72%. Amygdalar labeling was observed after tracer deposits throughout the IC, including its central nucleus (ICC). In comparison, labeling in the auditory cortex (layer V) was heavily ipsilateral (averaging 92%). Cortical labeling depended on the location of IC deposits: dorsomedial deposits resulted in the most labeled cells, whereas ventrolateral deposits labeled few or no cortical cells. Cortical labeling occurred after several deposits in the ICC. Across experiments, the average number of labeled cells in the amygdala was similar to that in the auditory cortex, indicating that the amygdalocollicular projection is significant. The results demonstrate a direct, widespread projection from the basal amygdala to the IC. They also suggest the presence of a rapid thalamoamygdalocollicular feedback circuit that may impose emotional content onto processing of sensory stimuli at a relatively low level of an ascending sensory pathway. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1523/jneurosci.22-23-10449.2002" target="_blank" rel="noreferrer noopener">10.1523/jneurosci.22-23-10449.2002</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). *Stilbamidines 2002 Acoustic Stimulation/methods Action Potentials/physiology Amygdala/*cytology/physiology Animals Auditory Cortex/cytology Auditory Pathways/*cytology/physiology Axonal Transport/physiology Brain Stem/cytology Chiroptera/*anatomy & histology/physiology Cholera Toxin/pharmacokinetics College of Anatomy & Neurobiology Department of Anatomy & Neurobiology Dextrans Electrodes Fluorescent Dyes Fuzessery Zoltan M Grose Carol D Implanted Inferior Colliculi/*cytology/physiology Marsh Robert A NEOMED College of Medicine Neurons/cytology/physiology Rhodamines Species Specificity The Journal of neuroscience : the official journal of the Society for Neuroscience Wenstrup Jeffrey J Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate