1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1997.272.3.H1412" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1997.272.3.H1412</a>
Pages
H1412–1418
Issue
3
Volume
272
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Daily exercise and gender influence postexercise cardiac autonomic responses in hypertensive rats.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-03
Subject
The topic of the resource
*Physical Conditioning; Animal; Animals; Atropine Derivatives/pharmacology; Autonomic Nervous System/drug effects/*physiopathology; Exercise Test; Female; Heart Rate/*drug effects; Heart/*innervation; Hypertension/genetics/*physiopathology; Inbred SHR; Male; Metoprolol/pharmacology; Nitroglycerin/pharmacology; Phenylephrine/pharmacology; Rats; Running; Sex Characteristics; Sympathetic Nervous System/drug effects/*physiopathology; Weight Loss
Creator
An entity primarily responsible for making the resource
Chen Y; Chandler M P; DiCarlo S E
Description
An account of the resource
The influence of daily spontaneous running (DSR) and gender on postexercise cardiac autonomic responses was examined in spontaneously hypertensive rats. Rats were weaned at 4-5 wk of age and were randomly assigned to a sedentary (7 males and 6 females) or DSR (7 males and 8 females) group. After 8 weeks of DSR or sedentary control, rats were chronically instrumented with arterial and venous catheters. After 5 days of recovery, cardiac sympathetic (ST) and parasympathetic tonus (PT) were determined (by the response of heart rate to receptor antagonists) on alternate days under two experimental conditions: no exercise and postexercise. After a single bout of dynamic treadmill exercise (12 m/min, 10% grade for 40 min) ST was reduced (P \textless 0.05) (male sedentary: no exercise 45 +/- 4 vs. postexercise 28 +/- 3 beats/min; female sedentary: no exercise 69 +/- 10 vs. postexercise 37 +/- 7 beats/ min). PT was also altered after exercise (male sedentary: no exercise -31 +/- 4 vs. postexercise -11 +/- 2 beats/min; female sedentary: no exercise -5 +/- 4 vs. postexercise 7 +/- 4 beats/min). After DSR, ST was reduced (male sedentary 45 +/- 4 vs. DSR 22 +/- 3 beats/min; female sedentary 69 +/- 10 vs. DSR 36 +/- 4 beats/min) (P \textless 0.05). Finally, male rats had a lower ST and higher PT than female rats. These results demonstrate that 1) ST was reduced after a single bout of dynamic exercise; 2) ST was reduced after DSR; 3) the autonomic response to acute exercise was attenuated after DSR; and 4) there was a gender influence on the cardiac autonomic function.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1997.272.3.H1412" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1997.272.3.H1412</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Physical Conditioning
1997
Animal
Animals
Atropine Derivatives/pharmacology
Autonomic Nervous System/drug effects/*physiopathology
Chandler M P
Chen Y
DiCarlo S E
Exercise Test
Female
Heart Rate/*drug effects
Heart/*innervation
Hypertension/genetics/*physiopathology
Inbred SHR
Male
Metoprolol/pharmacology
Nitroglycerin/pharmacology
Phenylephrine/pharmacology
Rats
Running
Sex Characteristics
Sympathetic Nervous System/drug effects/*physiopathology
The American journal of physiology
Weight Loss
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1994.266.2.H531" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1994.266.2.H531</a>
Pages
H531–539
Issue
2
Volume
266
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Myocardial work load is a major determinant of norepinephrine-induced left ventricular dysfunction.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-02
Subject
The topic of the resource
Anesthesia; Animals; Blood Pressure/*drug effects; Cardiovascular; Consciousness; Diastole/drug effects; Dose-Response Relationship; Drug; General; Heart Rate/*drug effects; Heart/drug effects/*physiology; Left/drug effects/*physiology; Models; Norepinephrine/*pharmacology; Pentobarbital; Rabbits; Systole/drug effects; Time Factors; Ventricular Function
Creator
An entity primarily responsible for making the resource
Bosso F J; Allman F D; Pilati C F
Description
An account of the resource
This study was conducted to determine whether increased myocardial energy demand plays a role in norepinephrine (NE)-induced left ventricular (LV) dysfunction. A range of arterial pressure-heart rate (P-R) products (myocardial energy demand) was produced in both conscious and pentobarbital sodium-anesthetized rabbits with the same dose of NE (10 micrograms priming bolus plus 2.5 micrograms.kg-1 x min-1 for 2.5 h). After NE treatment, LV function was evaluated in vitro and found to be markedly diminished in the rabbits that had an elevated P-R product. In contrast, LV function was not significantly affected when the P-R product was maintained near control levels during NE treatment. In separate experiments, rabbit hearts were isolated and exposed to NE (10,000 or 50,000 pg/ml) for 2.5 h under low P-R product conditions. These hearts exhibited a dose-dependent decrease in LV function that was modest compared with that observed in rabbits that had elevated P-R products during in vivo NE treatment. Our results suggest that high concentrations of NE may cause modest degrees of LV dysfunction independently of increases in myocardial energy demand, but the LV dysfunction is exacerbated when myocardial energy demand is elevated.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1994.266.2.H531" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1994.266.2.H531</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
Allman F D
Anesthesia
Animals
Blood Pressure/*drug effects
Bosso F J
Cardiovascular
Consciousness
Diastole/drug effects
Dose-Response Relationship
Drug
General
Heart Rate/*drug effects
Heart/drug effects/*physiology
Left/drug effects/*physiology
Models
Norepinephrine/*pharmacology
Pentobarbital
Pilati C F
Rabbits
Systole/drug effects
The American journal of physiology
Time Factors
Ventricular Function