1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/1744-9987.12763" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/1744-9987.12763</a>
Pages
4–21
Issue
1
Volume
23
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Atypical Hemolytic-Uremic Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment.
Publisher
An entity responsible for making the resource available
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-02
Subject
The topic of the resource
Atypical hemolytic uremic syndrome; Complement regulatory protein mutation; Eculizumab; Renal impairment; Thrombotic microangiopathy
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Krishnappa Vinod; Blaha Taryn; Kann Taylor; Hein William; Burke Linda; Bagga Arvind
Description
An account of the resource
Atypical hemolytic uremic syndrome (aHUS), a rare variant of thrombotic microangiopathy, is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. The condition is associated with poor clinical outcomes with high morbidity and mortality. Atypical HUS predominantly affects the kidneys but has the potential to cause multi-organ system dysfunction. This uncommon disorder is caused by a genetic abnormality in the complement alternative pathway resulting in over-activation of the complement system and formation of microvascular thrombi. Abnormalities of the complement pathway may be in the form of mutations in key complement genes or autoantibodies against specific complement factors. We discuss the pathophysiology, clinical manifestations, diagnosis, complications, and management of aHUS. We also review the efficacy and safety of the novel therapeutic agent, eculizumab, in aHUS, pregnancy-associated aHUS, and aHUS in renal transplant patients.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/1744-9987.12763" target="_blank" rel="noreferrer noopener">10.1111/1744-9987.12763</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2019
Atypical hemolytic uremic syndrome
Bagga Arvind
Blaha Taryn
Burke Linda
Complement regulatory protein mutation
Department of Internal Medicine
Eculizumab
Hein William
Kann Taylor
Krishnappa Vinod
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Raina Rupesh
Renal impairment
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Thrombotic microangiopathy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.5527/wjn.v7.i8.148" target="_blank" rel="noreferrer noopener">http://doi.org/10.5527/wjn.v7.i8.148</a>
Pages
148–154
Issue
8
Volume
7
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Palliative care for acute kidney injury patients in the intensive care unit.
Publisher
An entity responsible for making the resource available
World journal of nephrology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-12
Subject
The topic of the resource
Acute kidney injury; Advance directives; Dialysis; Intensive care unit; Palliative care
Creator
An entity primarily responsible for making the resource
Krishnappa Vinod; Hein William; DelloStritto Daniel; Gupta Mona; Raina Rupesh
Description
An account of the resource
Patients with acute kidney injury (AKI) in the intensive care unit (ICU) are often suitable for palliative care due to the high symptom burden. The role of palliative medicine in this patient population is not well defined and there is a lack of established guidelines to address this issue. Because of this, patients in the ICU with AKI deprived of the most comprehensive or appropriate care. The reasons for this are multifactorial including lack of palliative care training among nephrologists. However, palliative care in these patients can help alleviate symptoms, improve quality of life, and decrease suffering. Palliative care physicians can determine the appropriateness and model of palliative care. In addition to shared decision-making, advance directives should be established with patients early on, with specific instructions regarding dialysis, and those advance directives should be respected.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.5527/wjn.v7.i8.148" target="_blank" rel="noreferrer noopener">10.5527/wjn.v7.i8.148</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Acute kidney injury
Advance Directives
DelloStritto Daniel
Department of Internal Medicine
Dialysis
Gupta Mona
Hein William
Intensive care unit
Krishnappa Vinod
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Palliative Care
Raina Rupesh
World journal of nephrology