1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/toxsci/kfw031" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/toxsci/kfw031</a>
Pages
150–159
Issue
1
Volume
151
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
Publisher
An entity responsible for making the resource available
Toxicological sciences : an official journal of the Society of Toxicology
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-05
Subject
The topic of the resource
*cytochrome P450; *flavoenzymes; *heme; *nitric oxide synthase; *reactive oxygen species; Animals; Cytochrome P-450 Enzyme Inhibitors/*pharmacology; Cytochrome P-450 Enzyme System/*metabolism; Dose-Response Relationship; Drug; Heme/*antagonists & inhibitors/metabolism; Humans; Liver/drug effects/enzymology; Mice; Microsomes; Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism; Nitric Oxide/metabolism; Onium Compounds/*pharmacology; Rats; Recombinant Proteins/metabolism; Sprague-Dawley; Time Factors
Creator
An entity primarily responsible for making the resource
Szilagyi John T; Mishin Vladimir; Heck Diane E; Jan Yi-Hua; Aleksunes Lauren M; Richardson Jason R; Heindel Ned D; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
Cytochrome P450 (CYP) enzymes mediate mixed-function oxidation reactions important in drug metabolism. The aromatic heterocyclic cation, diphenyleneiodonium (DPI), binds flavin in cytochrome P450 reductase and inhibits
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/toxsci/kfw031" target="_blank" rel="noreferrer noopener">10.1093/toxsci/kfw031</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*cytochrome P450
*flavoenzymes
*heme
*nitric oxide synthase
*Reactive oxygen species
2016
Aleksunes Lauren M
Animals
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Cytochrome P-450 Enzyme System/*metabolism
Department of Pharmaceutical Sciences
Dose-Response Relationship
Drug
Heck Diane E
Heindel Ned D
Heme/*antagonists & inhibitors/metabolism
Humans
Jan Yi-Hua
Laskin Debra L
Laskin Jeffrey D
Liver/drug effects/enzymology
Mice
Microsomes
Mishin Vladimir
NEOMED College of Pharmacy
Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism
Nitric Oxide/metabolism
Onium Compounds/*pharmacology
Rats
Recombinant Proteins/metabolism
Richardson Jason R
Sprague-Dawley
Szilagyi John T
Time Factors
Toxicological sciences : an official journal of the Society of Toxicology