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Text
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URL Address
<a href="http://doi.org/10.1001/archinte.168.11.1137" target="_blank" rel="noreferrer noopener">http://doi.org/10.1001/archinte.168.11.1137</a>
Pages
1137–1144
Issue
11
Volume
168
Dublin Core
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Title
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The treatment of herpes simplex infections: an evidence-based review.
Publisher
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Archives of Internal Medicine
Date
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2008
2008-06
Subject
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2-Aminopurine/analogs & derivatives/therapeutic use; Acyclovir/analogs & derivatives/therapeutic use; Antiviral Agents/*therapeutic use; Drug Resistance; Evidence-Based Medicine; Famciclovir; Herpes Genitalis/*drug therapy; Herpes Labialis/*drug therapy; Humans; Recurrence; Risk Factors; Valacyclovir; Valine/analogs & derivatives/therapeutic use; Viral
Creator
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Cernik Christina; Gallina Kelly; Brodell Robert T
Description
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Genital and labial herpes simplex virus infections are frequently encountered by primary care physicians in the United States. Whereas the diagnosis of this condition is often straightforward, choosing an appropriate drug (eg, acyclovir, valacyclovir hydrochloride, or famciclovir) and dosing regimen can be confusing in view of (1) competing clinical approaches to therapy; (2) evolving dosing schedules based on new research; (3) approved regimens of the Food and Drug Administration that may not match recommendations of the Centers for Disease Control and Prevention or of other experts; and (4) dissimilar regimens for oral and genital infections. The physician must first choose an approach to treatment (ie, intermittent episodic therapy, intermittent suppressive therapy, or chronic suppressive therapy) based on defined clinical characteristics and patient preference. Then, an evidence-based dosing regimen must be selected. In this review, data from all sources are tabulated to provide a handy clinical reference.
Identifier
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<a href="http://doi.org/10.1001/archinte.168.11.1137" target="_blank" rel="noreferrer noopener">10.1001/archinte.168.11.1137</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2-Aminopurine/analogs & derivatives/therapeutic use
2008
Acyclovir/analogs & derivatives/therapeutic use
Antiviral Agents/*therapeutic use
Archives of internal medicine
Brodell Robert T
Cernik Christina
Department of Internal Medicine
Drug Resistance
Evidence-Based Medicine
Famciclovir
Gallina Kelly
Herpes Genitalis/*drug therapy
Herpes Labialis/*drug therapy
Humans
NEOMED College of Medicine
Recurrence
Risk Factors
Valacyclovir
Valine/analogs & derivatives/therapeutic use
Viral