1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.bmcl.2014.03.021" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.bmcl.2014.03.021</a> Pages 2163–2167 Issue 9 Volume 24 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A novel Lipoprotein lipase (LPL) agonist rescues the enzyme from inhibition by angiopoietin-like 4 (ANGPTL4). Publisher An entity responsible for making the resource available Bioorganic & medicinal chemistry letters Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-05 Subject The topic of the resource Angiopoietin-like 4 Protein; Angiopoietins/*metabolism; ANGPTL4; Atherosclerosis; Benzamides/pharmacology; Drug Discovery; Enzyme Activation/*drug effects; High-throughput screen; Homology model; Humans; Ibrolipim; Lipoprotein Lipase/*metabolism; LPL; Molecular Docking Simulation; NO-1886; Organophosphorus Compounds/pharmacology Creator An entity primarily responsible for making the resource Geldenhuys Werner J; Aring Danielle; Sadana Prabodh Description An account of the resource Lipoprotein lipase (LPL) is a key physiological regulator of triglycerides and atherosclerosis risk. Random screening identified a compound designated C10, showing greater LPL agonist activity than NO-1886, a known LPL agonist. Structure-activity relationship (SAR) exploration of C10 led to the identification of C10d exhibiting at least two fold greater LPL activation than Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.bmcl.2014.03.021" target="_blank" rel="noreferrer noopener">10.1016/j.bmcl.2014.03.021</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). 2014 Angiopoietin-like 4 Protein Angiopoietins/*metabolism ANGPTL4 Aring Danielle Atherosclerosis Benzamides/pharmacology Bioorganic & medicinal chemistry letters Department of Pharmaceutical Sciences Department of Pharmacy Practice Drug Discovery Enzyme Activation/*drug effects Geldenhuys Werner J High-throughput screen Homology model Humans Ibrolipim Lipoprotein Lipase/*metabolism LPL Molecular Docking Simulation NEOMED College of Graduate Studies NEOMED College of Pharmacy NO-1886 Organophosphorus Compounds/pharmacology Sadana Prabodh