1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1007/s10856-015-5460-0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s10856-015-5460-0</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 9-9 Issue 3 Volume 26 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Infusion of iodine-based contrast agents into poly(p-dioxanone) as a radiopaque resorbable IVC filter Publisher An entity responsible for making the resource available Journal of Materials Science-Materials in Medicine Date A point or period of time associated with an event in the lifecycle of the resource 2015 2015-03 Subject The topic of the resource degradation; Engineering; in-vivo; Materials Science; release; triclosan; vena-cava filters Creator An entity primarily responsible for making the resource Singhana B; Chen A; Slattery P; Yazdi I K; Qiao Y; Tasciotti E; Wallace M; Huang S; Eggers M; Melancon M P Description An account of the resource To determine the feasibility of infusing resorbable inferior vena cava (IVC) filter with iodine-based contrast agents to produce a radiopaque, computed tomography (CT)-visible IVC filter. Infused poly(p-dioxanone) (PPDO) was obtained by incubating PPDO in different concentrations of 4-iodobenzoyl chloride (IBC) and 2,3,5-triiodobenzoic acid (TIBA). Characterizations of infused and nascent PPDO were done using elemental analysis, micro-CT, tensile strength analysis, scanning electron microscopy, and differential scanning calorimetry. Elemental analysis showed percentage loading of 1.07 +/- 0.08 for IBC and 0.73 +/- 0.01 for TIBA. The iodine loading remained the same within 2 weeks for TIBA but decreased to about 80 % with IBC when subjected to physiological conditions. Micro-CT images showed increased attenuation of the infused PPDO compared with the nascent PPDO. The Hounsfield unit values for infused and nascent sutures were 110 +/- 40 and 153 +/- 53 for PPDO infused with 2 mg/mL IBC and TIBA, respectively, but only 11.35 +/- 2 for nascent PPDO. In contrast the HU for bone was 116 +/- 37. Tensile strength analysis showed maximum loads of 1.01 +/- 0.43 kg and 10.02 +/- 0.54 kg for IBC and TIBA, respectively, and 10.10 +/- 0.64 kg for nascent PPDO. Scanning electron microscopy showed that the morphology of the PPDO surface did not change after coating and preliminary cytotoxicity assay showed no killing effect on Hela cells. PPDO infused with a contrast agent is significantly more radiopaque than nascent PPDO on micro-CT imaging. This radiopacity could allow the position and integrity of infused resorbable IVC filter to be monitored while it is in place, thus increasing its safety and efficacy as a medical device. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1007/s10856-015-5460-0" target="_blank" rel="noreferrer noopener">10.1007/s10856-015-5460-0</a> Format The file format, physical medium, or dimensions of the resource Journal Article 2015 Chen A degradation Eggers M Engineering Huang S in-vivo Journal Article Journal of Materials Science-Materials in Medicine Materials Science Melancon M P Qiao Y release Singhana B Slattery P Tasciotti E triclosan vena-cava filters Wallace M Yazdi I K