Browse Items · NEOMED Bibliography Database

Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease.

Traumatic brain injury (TBI) has acute and chronic sequelae, including an increased risk for the development of Alzheimer's disease (AD). TBI-associated neuroinflammation is characterized by activation of brain-resident microglia and infiltration of…

Calretinin-immunoreactive nerves in the uterus, pelvic autonomic ganglia, lumbosacral dorsal root ganglia and lumbosacral spinal cord.

Nerves containing the calcium-binding protein calretinin have been reported in several organs but not in female reproductive organs and associated ganglia. This study was undertaken to determine if nerves associated with the uterus contain calretinin…

Characterization of ex vivo-generated bovine and human cartilage by immunohistochemical, biochemical, and magnetic resonance imaging analyses.

Osteoarthritis (OA) is a prevalent age-associated disease involving altered chondrocyte homeostasis and cartilage degeneration. The avascular nature of cartilage and the altered chondrocyte phenotype characteristic of OA severely limit the capacity…

Characterization of vascular endothelial growth factor (VEGF) in the uterine cervix over pregnancy: effects of denervation and implications for cervical ripening.

Bilateral neurectomy of the pelvic nerve (BLPN) that carries uterine cervix-related sensory nerves induces dystocia, and administration of its vasoactive neuropeptides induces changes in the cervical microvasculature, resembling those that occur in…

Tags: 2004, Animal/*metabolism, Animals, Cervical Ripening/*metabolism, Cervix Uteri/blood supply/innervation/*metabolism, Denervation, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme-Linked Immunosorbent Assay, Female, Hattori Y, Immunohistochemistry, Jesmin S, Microcirculation, Mowa C N, NEOMED College of Medicine, Nitric Oxide Synthase Type III, Nitric Oxide Synthase/biosynthesis, Papka R, Phosphorylation, Pregnancy, Protein Isoforms/biosynthesis/metabolism, Protein-Serine-Threonine Kinases/biosynthesis, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/biosynthesis, Rats, Reverse Transcriptase Polymerase Chain Reaction, Sakuma I, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Togashi H, Usip S, Vascular Endothelial Growth Factor A/biosynthesis/*metabolism, Vascular Endothelial Growth Factor Receptor-2/biosynthesis, Wistar, Yoshioka M

Cholinergic cells in the tegmentum send branching projections to the inferior colliculus and the medial geniculate body.

The pontomesencephalic tegmentum (PMT) provides cholinergic input to the inferior colliculus (IC) and the medial geniculate body (MG). PMT cells are often characterized as projecting to more than one target. The purpose of this study was to determine…

Tags: 2011, Acetylcholine/metabolism, Animals, Auditory Pathways/*cytology, Department of Anatomy & Neurobiology, Female, Geniculate Bodies/*cytology, Guinea Pigs, Immunohistochemistry, Inferior Colliculi/*cytology, Male, Motts S D, NEOMED College of Medicine, Neurons/*cytology/metabolism, Neuroscience, Schofield B R, Tegmentum Mesencephali/*cytology

Contributions of paleorheumatology to understanding contemporary disease.

As paleopathology has evolved from observational speculation to analysis of testable hypotheses, so too has recognition of its contribution to vertebrate paleontology. In the presence of significant structural and density variation (between matrix…

Detection of single mRNAs in individual cells of the auditory system.

Gene expression analysis is essential for understanding the rich repertoire of cellular functions. With the development of sensitive molecular tools such as single-cell RNA sequencing, extensive gene expression data can be obtained and analyzed from…

Distribution and origin of corticotropin-releasing factor-immunoreactive axons in the female rat lumbosacral spinal cord.

Corticotropin-releasing factor (CRF) is a neuropeptide traditionally known for its hormonal role in the hypothalamic/pituitary/adrenal stress axis. However, CRF has been reported in axons in sites that may be considered outside of the direct stress…

Distribution of tyrosine hydroxylase- and serotonin-immunoreactive cells in the central nervous system of the thornback guitarfish, Platyrhinoidis triseriata.

Brainstem reticular nuclei of amniotes (mammals, birds and reptiles) may share a common phylogenetic origin as demonstrated by their many shared features (hodology, cytoarchitectonics, presence of neurochemicals). By studying characteristics of these…

Tags: 1990, Animals, Central Nervous System/cytology/*metabolism, Cruce W L, Fishes/*metabolism, Immunohistochemistry, Journal of chemical neuroanatomy, Northcutt R G, Serotonin/*metabolism, Stuesse S L, Tyrosine 3-Monooxygenase/*metabolism

Effect of aging on the substance P receptor, NK-1, in the spinal cord of rats with peripheral nerve injury.

Substance P (SP) levels in the spinal cords of very old rats are less than the levels in younger rats (Bergman et al., 1996). After injury to a peripheral nerve in young rats, immunoreactivity (ir) to the SP receptor, NK-1 (neurokinin-1), increases…

Estrogen receptor-alpha and beta- immunoreactivity and mRNA in neurons of sensory and autonomic ganglia and spinal cord.

Estrogen receptor-alpha immunoreactivity and mRNAs are present in neurons in locales that innervate genital organs, e.g., parasympathetic pelvic autonomic ganglia, sensory dorsal root and nodose ganglia, and autonomic areas of the lumbosacral spinal…

Estrogen receptor-alpha and neural circuits to the spinal cord during pregnancy.

Estrogen receptor immunoreactivity and mRNAs are present in spinal cord neurons in locations that are associated with sensory and autonomic innervation of female reproductive organs. The present study was undertaken to examine the expression of…

Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.

A peculiar hyaline sarcoplasmic inclusion in the atrial myocytes of old female Syrian hamsters is described. This type of inclusion resembles that described in rare human cardiomyopathy. They have also been described in other rodents and have been…

Tags: 1994, Animals, Cricetinae, Female, Gilloteaux J, Heart Atria/metabolism/*ultrastructure, Immunoelectron, Immunohistochemistry, Inclusion Bodies/metabolism/*ultrastructure, Jennes L, Male, Mesocricetus, Microscopy, Stoeckel M E, Ultrastructural pathology, Vanderhaeghen J J

Gastric Lipoma: A Review of the Literature.

Gastric lipoma is a rare benign tumor of the stomach. The imaging characteristics are diagnostic because the lesion has fat attenuation on computed tomography and demonstrates characteristics of fat on magnetic resonance images. On ultrasound, the…

Hypothalamic paraventricular axons projecting to the female rat lumbosacral spinal cord contain oxytocin immunoreactivity.

Oxytocin-containing axons project from the hypothalamic paraventricular nucleus to the neurohypophysis and thoracic spinal cord to ultimately influence uterine contractions and autonomic activity, respectively. Whether or not oxytocin-immunoreactive…

Tags: *Synaptic Transmission, 2001, Animals, Axons/*physiology, Female, Immunohistochemistry, Journal of neuroscience research, Lumbosacral Region, Nerve Fibers/metabolism/physiology, Oxytocin/*metabolism, Papka R E, Paraventricular Hypothalamic Nucleus/*physiology, Puder B A, Rats, Spinal Cord/*physiology, Sprague-Dawley

Images in cytology. Fine-needle aspiration of a lumbar chordoma.

Tags: 2010, Biopsy, Chordoma/diagnosis/*pathology, Diagnosis, Diagnostic cytopathology, Differential, Female, Fine-Needle, Ganesan Santhi, Humans, Immunohistochemistry, Lumbar Vertebrae/*pathology, Middle Aged, Moonda Afreen H

Immunohistochemical distribution of enkephalin, substance P, and somatostatin in the brainstem of the leopard frog, Rana pipiens.

The brainstems of frogs contain many of the neurochemicals that are found in mammals. However, the clustering of nuclei near the ventricles makes it difficult to distinguish individual cell groups. We addressed this problem by combining…

Tags: *Stilbamidines, 2001, Adli D S, Animals, Brain Stem/*chemistry/cytology, Cruce W L, Enkephalins/*analysis, Fluorescent Dyes, Immunohistochemistry, Male, Microscopy research and technique, Rana pipiens/*metabolism, Somatostatin/*analysis, Spinal Cord/chemistry/cytology, Stuesse S L, Substance P/*analysis

Immunohistochemical localization of serotonin, leu-enkephalin, tyrosine hydroxylase, and substance P within the visceral sensory area of cartilaginous fish.

We examined the distribution of immunoreactivity to serotonin (5-HT), leu-enkephalin (LENK), tyrosine-hydroxylase (TH), and substance P (SP) within the primary visceral sensory region of cartilaginous fish. Two genera of sharks, Squalus and…

Tags: *Brain Chemistry, 1992, Animals, Antibodies, Brain Stem/cytology, Cell and tissue research, Cruce W L, Enkephalin, Fishes, Immunohistochemistry, Leucine/*analysis, Medulla Oblongata/cytology, Serotonin/*analysis, Stuesse D C, Stuesse S L, Substance P/*analysis, Tyrosine 3-Monooxygenase/*analysis

Immunohistochemical localization of serotoninergic, enkephalinergic, and catecholaminergic cells in the brainstem and diencephalon of a cartilaginous fish, Hydrolagus colliei.

We localized serotonin (5-HT), leu-enkephalin (LENK), and tyrosine hydroxylase (TH) immunoreactive cells in the brain of a holocephalian, Hydrolagus colliei, by use of antibodies made in rabbit and the peroxidase-antiperoxidase technique. Only three…

Tags: 1991, Animals, Brain Stem/cytology/*metabolism, Catecholamines/*metabolism, Cruce W L, Diencephalon/cytology/*metabolism, Enkephalins/*metabolism, Female, Fishes/*metabolism, Immunohistochemistry, Male, Neurons/metabolism, Serotonin/*metabolism, Stuesse S L, The Journal of comparative neurology, Tissue Distribution

Immunoreactivity Of Bufo-marinus Heart For Atrial-natriuretic-factor

Tags: 1991, amphibian, atrial natriuretic factor, Belgian Journal of Zoology, body, factor anf, frog-heart, Gilloteaux J, heart, Immunohistochemistry, localization, peptide, ventricles, water regulation, Zoology

Iron localization in superficial siderosis of the central nervous system.

Originally conceived as an uncommon disorder, with the advent of MRI, CNS superficial siderosis has been observed more frequently. We present histologic, histochemical, immunohistochemical, immunofluorescent and ultrastructural evaluation of a…

Light and electron microscopical immunolocalization of neuropeptide Y-containing nerves in the hamster gallbladder.

Neuropeptide Y (NPY)-containing nerve structures were detected in the Syrian hamster gallbladder by using peroxidase-antiperoxidase immunohistochemical staining and immunoelectron microscopic techniques. In addition, Alcian blue-P.A.S. was used to…

Melanotic schwannoma. An unusual case of an ossified soft tissue mass.

A case of a melanotic schwannoma presenting as a soft tissue mass of the abductors of the hip is reported. The radiographic findings suggested myositis ossificans, but several subtle findings raised the concern for something else. A bilobed…

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.

OBJECTIVE: Hedgehog (HH) signaling has recently been associated with cartilage degradation in osteoarthritis (OA). Because interleukin-1beta (IL-1beta) has been implicated as a principal instigator of OA, we sought to determine whether

Tags: 2015, Academic Medical Centers, Aged, Akhtar Nahid, Analysis of Variance, Animal, Animals, Anterior Cruciate Ligament/surgery, Arthritis & rheumatology (Hoboken, N.J.), Blotting, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism/pathology, Cultured, Department of Anatomy & Neurobiology, Disease Models, Female, Funding Source, Gene Expression Regulation/genetics/*physiology, Haqqi Tariq M, Hedgehog Proteins/genetics/*metabolism, HEK293 Cells, Human, Humans, Immunohistochemistry, In Vitro Techniques, Interleukin-1beta/pharmacology, Knee/etiology/*metabolism/pathology, Makki Mohammad S, Male, Matrix Metalloproteinase 13/metabolism, MicroRNAs/genetics/*metabolism, Middle Age, Middle Aged, NEOMED College of Medicine, Ohio, Open Reading Frames/genetics/*physiology, Osteoarthritis, Osteoarthritis – Epidemiology, Osteoarthritis – Physiopathology, Polymerase Chain Reaction, Rabbits, Signal Transduction/genetics/physiology, T-Tests, Transfection, Up-Regulation/drug effects/genetics/physiology, Western

Multiple origins of cholinergic innervation of the cochlear nucleus.

Acetylcholine (Ach) affects a variety of cell types in the cochlear nucleus (CN) and is likely to play a role in numerous functions. Previous work in rats suggested that the acetylcholine arises from cells in the superior olivary complex, including…

Tags: *Cholinergic Fibers, 2011, Acetylcholine/metabolism, Animals, Auditory Pathways/*cytology/metabolism, Cochlear Nucleus/*anatomy & histology/metabolism, Department of Anatomy & Neurobiology, Guinea Pigs, Immunohistochemistry, Mellott J G, Motts S D, NEOMED College of Medicine, Neuroscience, Schofield B R

Neuropathic pain in aged rats: behavioral responses and astrocytic activation.

We used the Bennett and Xie (1988) model of chronic neuropathic pain to study the effect of age on thermal and tactile sensitivity and on astrocytic activation in the dorsal horn of the spinal cord after nerve injury. Fischer 344 FBNF1 hybrid rats in…

Overexpression of beta-catenin and cyclinD1 predicts a poor prognosis in ovarian serous carcinomas.

UNLABELLED: Ovarian serous cancer is the most common subtype of epithelial ovarian cancer, and is the leading cause of death from gynecologic cancer. There is an important need for exploration of diagnostic and prognostic markers for this disease.…

P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy.

ATP, an intracellular energy source, is released from cells during tissue stress, damage, or inflammation. The P2X subtype of the ATP receptor is expressed in rat dorsal root ganglion (DRG) cells, spinal cord dorsal horn, and axons in peripheral…

Painful Cutaneous Nodule of the Jawline.

Tags: 2016, Adult, Biopsy, Cernik Christina, Department of Internal Medicine, Diagnosis, Differential, Facial Dermatoses – Diagnosis, Facial Dermatoses – Pathology, Facial Dermatoses/diagnosis/pathology, Female, Hereditary – Diagnosis, Hereditary – Pathology, Hereditary/diagnosis/*pathology, Humans, Immunohistochemistry, JAMA dermatology, Kunzler Elaine, Leiomyoma – Diagnosis, Leiomyoma – Pathology, Leiomyomatosis/diagnosis/*pathology, Neck – Pathology, Neck/pathology, Needle, NEOMED College of Medicine, Neoplastic Syndromes, Skin Abnormalities – Diagnosis, Skin Abnormalities – Pathology, Skin Abnormalities/diagnosis/*pathology, Skin Neoplasms – Diagnosis, Skin Neoplasms – Pathology, Skin Neoplasms/diagnosis/*pathology, Uterine Neoplasms – Diagnosis, Uterine Neoplasms – Pathology, Uterine Neoplasms/diagnosis/*pathology, Weaver Joshua

Pertubation of beta1 integrin function using anti-sense or function-blocking antibodies on corneal cells grown on fibronectin and tenascin.

During corneal development, neural crest derivatives from the periocular mesenchyme migrate into the cornea and differentiate into corneal fibroblasts. During this time, these cells interact with a variety of extracellular matrices for proper…

Pilomatricoma of the upper arm in an orthopaedic clinic.

Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway.

Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.

Breast cancer is the second leading cause of cancer-related death in women in the United States and discovery and development of safe chemopreventive drugs is urgently needed. The fruit pomegranate (Punica granatum) is gaining importance because of…

Projections from auditory cortex to cholinergic cells in the midbrain tegmentum of guinea pigs.

Anterograde and retrograde tracing techniques were used to characterize projections from the auditory cortex to the pedunculopontine and laterodorsal tegmental nuclei (PPT and LDT, respectively) in the midbrain tegmentum in guinea pigs. For…

Projections from auditory cortex to midbrain cholinergic neurons that project to the inferior colliculus.

We have shown that auditory cortex projects to cholinergic cells in the pedunculopontine tegmental nucleus (PPT) and laterodorsal tegmental nucleus (LDT). PPT and LDT are the sources of cholinergic projections to the inferior colliculus, but it is…

Projections from the medial agranular cortex to brain stem visuomotor centers in rats.

Projections from medial agranular cortex to brain stem in rat were determined by use of the anterograde tracers Phaseolus vulgaris leucoagglutinin, or wheat germ agglutinin conjugated horseradish peroxidase. Axonal trajectories were also followed by…

Tags: 1990, Animals, Brain Stem/*cytology, Cerebral Cortex/*cytology, Experimental brain research, Female, Horseradish Peroxidase, Immunohistochemistry, Inbred Strains, Male, Newman D B, Phytohemagglutinins, Rats, Stuesse S L, Visual Pathways/*anatomy & histology, Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate, Wheat Germ Agglutinins

Quantification of vasoactive intestinal peptide immunoreactivity in the anterior pituitary glands of intact male and female, ovariectomized, and estradiol benzoate-treated rats.

There are considerable data suggesting that vasoactive intestinal peptide (VIP) is involved in the regulation of PRL secretion; however, the role and cell of origin of anterior pituitary VIP remain to be determined. Immunocytochemical (ICC) studies…

Tags: *Ovariectomy, 1992, Animals, Anterior/*chemistry/drug effects/metabolism, Carrillo A J, Diestrus, Endocrinology, Estradiol/*pharmacology, Female, Immunohistochemistry, Inbred Strains, Male, Phelps C J, Pituitary Gland, Prolactin/blood/metabolism, Rats, Vasoactive Intestinal Peptide/*analysis/metabolism

Raphe nuclei in three cartilaginous fishes, Hydrolagus colliei, Heterodontus francisci, and Squalus acanthias.

The vertebrate reticular formation, containing over 30 nuclei in mammals, is a core brainstem area with a long evolutionary history. However, not all reticular nuclei are equally old. Nuclei that are widespread among the vertebrate classes are…

Tags: *Biological Evolution, 1995, Animals, Cruce W L, Dogfish/*anatomy & histology/metabolism, Elasmobranchii/*anatomy & histology/metabolism, Enkephalin, Immunohistochemistry, Leucine/analysis, Raphe Nuclei/*anatomy & histology/chemistry, Serotonin/analysis, Sharks/*anatomy & histology/metabolism, Stuesse D C, Stuesse S L, The Journal of comparative neurology

Real-time ultrasound elasticity of the breast: initial clinical results.

PURPOSE: To determine the sensitivity and specificity of a real-time elasticity imaging (EI) ultrasound (US) system in the characterization of breast lesions as benign or malignant. METHODS: A total of 208 patients with 251 lesions were scheduled to…

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.

Hepatocellular carcinoma (HCC) is one of the most common cancers and lethal diseases. In view of the limited treatment and a grave prognosis of liver cancer, preventive control has been emphasized. Resveratrol, a polyphenol found in grape skins,…

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